Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mark J. Gardner"'
Autor:
Xiaokui Mo, Yu Cao, Lai-Chu Wu, Giancarlo R. Valiente, Mark J. Gardner, Michael Bruss, Nicholas A. Young, Wael N. Jarjour, Zhongfa Liu, William L. Willis
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111559 (2014)
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Despite the widespread use of curcumin for centuries in Eastern medicine as an anti-inflammatory agent, its molecular actions and therapeutic viability have only recently been explored. While curcumin does have potential therapeutic efficacy, both so
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 36(7)
Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, was investigated in male volunteers after p.o. administration of a single 20-mg dose of [(14)C]lasofoxifene. Approximately 72% of the administered dose was recovere
Publikováno v:
Journal of the American Academy of Child and Adolescent Psychiatry. 33(6)
Objective To evaluate the magnitude and clinical significance of methylphenidate (MPH) effects on the classroom behavior and academic performance of 76 children with attention deficit disorder/hyperactivity (ADDH). Method A double-blind, placebo cont
Autor:
Nicholas Gerber, Jeffrey D. Lazar, Glen Apseloff, Donald M. Hilligoss, Mark J. Gardner, Eugenia B. Henry, Philip B. Inskeep
Publikováno v:
Journal of clinical pharmacology. 31(4)
The effects of rifampin on the pharmacokinetics of fluconazole were analyzed in an open-label, placebo-controlled, parallel study. Sixteen healthy male volunteers, randomized into two groups, received 200 mg of oral fluconazole on days 1 and 22. On d
Autor:
Harvey R. Goldstein, John H. Wilton, Eugenia B. Henry, Jerome J. Schentag, Becky M. Florentino, Mark J. Gardner, Donald M. Hilligoss, David T. D'andrea, Robert A. Blum
Publikováno v:
Annals of Internal Medicine. 114:755
Two orally active antifungal agents are currently available, ketoconazole and fluconazole. However, the absorption of ketoconazole depends on gastric pH for tablet disintegration and dissolution (1...
Autor:
William J. Jusko, Robin D'Ambrosio, Mark J. Gardner, Roman Kanarkowski, Kathleen M. Tornatore
Publikováno v:
Clinical Pharmacology and Therapeutics. 43:23-31
The effects of tobacco and oral contraceptive (OC) use (Ovral) on the pharmacokinetics of levonorgestrel (0.25 mg) and ethinyl estradiol (50 micrograms) were examined. Young women (n = 27) were grouped as follows: I: non-OC users/nonsmokers; II: OC u
Autor:
Mark J. Gardner, Kevin L. Kelly, J.T. Jones, Michael S. Shea, George J. DuPaul, Susan B. Tucker, Mark D. Rapport
Publikováno v:
Journal of Clinical Child Psychology. 16:329-338
We examined the effects of a range of methylphenidate (MPH) doses on attention deficit disordered-hyperactive (ADDH) children's attention in school and on Continuous Performance Test (CPT) performance in a clinic setting. Forty-two ADDH 6- to 11-year
Autor:
Beverly Paigen, Anthony M. Yurchak, Mary Linda Stotter Cuddy, William J. Jusko, Mark J. Gardner, Antoinette Mangione
Publikováno v:
Biopharmaceutics & Drug Disposition. 5:345-355
The pharmacokinetics of theophylline were compared in 11 residents living near a chemical waste site (Love Canal) and 25 control subjects from Western New York. Love Canal residents had documented chronic exposure to a variety of organic and halogena
Publikováno v:
British Journal of Clinical Pharmacology. 16:271-280
The independent as well as interactive effects of chronic (greater than 6 months) oral contraceptive (OC) use and cigarette smoking on single-dose (4 mg/kg) theophylline disposition were assessed in 49 young, healthy women. Significant elevations (40
Publikováno v:
Journal of Pharmaceutical Sciences. 72:348-350
A zinc-containing salt of theophylline, Zn(II)-aminophylline, was synthesized and its structure determined by X-ray diffraction techniques. The zinc ion is coordinated to two theophylline anions and a molecule of ethylenediamine in a tetrahedral arra