Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Mark J. Dunning"'
Autor:
Joseph J. Tonge, Scott V. Notley, Mark J. Dunning, Ana López-Guajardo, Jessica D. Medcalf, Paraskevi Heldin, George Panoutsos, Annica K. B. Gad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Infantile fibrosarcoma is a rare childhood tumour that originates in the fibrous connective tissue of the long bones for which there is an urgent need to identify novel therapeutic targets. This study aims to clarify the role of the extracel
Externí odkaz:
https://doaj.org/article/73e613197a564c4189d7259d2152523b
Autor:
Sokratis Kariotis, Emmanuel Jammeh, Emilia M. Swietlik, Josephine A. Pickworth, Christopher J. Rhodes, Pablo Otero, John Wharton, James Iremonger, Mark J. Dunning, Divya Pandya, Thomas S. Mascarenhas, Niamh Errington, A. A. Roger Thompson, Casey E. Romanoski, Franz Rischard, Joe G. N. Garcia, Jason X.-J. Yuan, Tae-Hwi Schwantes An, Ankit A. Desai, Gerry Coghlan, Jim Lordan, Paul A. Corris, Luke S. Howard, Robin Condliffe, David G. Kiely, Colin Church, Joanna Pepke-Zaba, Mark Toshner, Stephen Wort, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins, Allan Lawrie, Dennis Wang, UK National PAH Cohort Study Consortium
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Idiopathic pulmonary arterial hypertension is a rare and fatal disease with a heterogeneous treatment response. Here the authors show that unsupervised machine learning of whole blood transcriptomes from 359 patients with idiopathic pulmonary arteria
Externí odkaz:
https://doaj.org/article/f8e37550b75b47d2a53cbd19d4302aa9
Autor:
Sokratis Kariotis, Emmanuel Jammeh, Emilia M. Swietlik, Josephine A. Pickworth, Christopher J. Rhodes, Pablo Otero, John Wharton, James Iremonger, Mark J. Dunning, Divya Pandya, Thomas S. Mascarenhas, Niamh Errington, A. A. Roger Thompson, Casey E. Romanoski, Franz Rischard, Joe G. N. Garcia, Jason X.-J. Yuan, Tae-Hwi Schwantes An, Ankit A. Desai, Gerry Coghlan, Jim Lordan, Paul A. Corris, Luke S. Howard, Robin Condliffe, David G. Kiely, Colin Church, Joanna Pepke-Zaba, Mark Toshner, Stephen Wort, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins, Allan Lawrie, Dennis Wang, UK National PAH Cohort Study Consortium
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/cc1c89b6164a4d8d9937f26685d4f667
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5225 (2021)
Systemic cobalt (Co) and chromium (Cr) concentrations may be elevated in patients with metal joint replacement prostheses. Several studies have highlighted the detrimental effects of this exposure on bone cells in vitro, but the underlying mechanisms
Externí odkaz:
https://doaj.org/article/8f4b75ed9c0844138a41e6d6894bd4f0
Autor:
Mark J. Dunning, Sarah L. Vowler, Emilie Lalonde, Helen Ross-Adams, Paul Boutros, Ian G. Mills, Andy G. Lynch, Alastair D. Lamb
Publikováno v:
EBioMedicine, Vol 17, Iss C, Pp 5-6 (2017)
Externí odkaz:
https://doaj.org/article/744a1ff0ba3b4280a7b581afa3a125c4
Publikováno v:
Revstat Statistical Journal, Vol 4, Iss 1 (2006)
The Illumina BeadArrayTM platform is a novel microarray technology based on randomly assembled arrays of beads. Each bead on the array carries copies of a single gene-specific probe with, on average, about 30 replicates of each bead type on an array.
Externí odkaz:
https://doaj.org/article/2c27ef06c58341fa969648faae0bb184
Autor:
Sarah Jurmeister, Antonio Ramos‐Montoya, Chiranjeevi Sandi, Nelma Pértega‐Gomes, Karan Wadhwa, Alastair D Lamb, Mark J Dunning, Jan Attig, Jason S Carroll, Lee GD Fryer, Sérgio L Felisbino, David E Neal
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-18 (2018)
Abstract Genetically engineered mouse models of cancer can be used to filter genome‐wide expression datasets generated from human tumours and to identify gene expression alterations that are functionally important to cancer development and progress
Externí odkaz:
https://doaj.org/article/f4f3abda48f3447a8e0ee97abf3bc7cf
Autor:
Thomas Payne, Matthew Appleby, Ellen Buckley, Linda M.A. van Gelder, Benjamin H. Mullish, Matilde Sassani, Mark J. Dunning, Dena Hernandez, Sonja W. Scholz, Alisdair McNeill, Vincenzo Libri, Sarah Moll, Julian R. Marchesi, Rosie Taylor, Li Su, Claudia Mazzà, Thomas M. Jenkins, Thomas Foltynie, Oliver Bandmann
Publikováno v:
Movement Disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c04727dae41621f9d3cafd9959052a87
https://doi.org/10.1002/mds.29450
https://doi.org/10.1002/mds.29450
Autor:
Marco Henneke, Stephen A. Renshaw, Noémie Hamilton, Jessica J. Petts, Thomas Weber, Mark J Dunning, Jutta Gärtner, Hannah M. Isles, Holly A. Rutherford
Publikováno v:
Glia
The contribution of microglia in neurological disorders is emerging as a leading disease driver rather than a consequence of pathology. RNAseT2‐deficient leukoencephalopathy is a severe childhood white matter disorder affecting patients in their fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fbd5a30c2826788d69b9c6a2c1a9e6
https://doi.org/10.1002/glia.23829
https://doi.org/10.1002/glia.23829
Autor:
Yinan Li, Cheol Kwak, Lisa A. Porter, Abdulkadir Hussein, Yuzhuo Wang, Hyewon Youn, Xuesen Dong, Keon Wook Kang, Alastair D. Lamb, Chang Wook Jeong, Gi Jeong Cheon, Mohamadreza K. Bakht, Iulian Derecichei, Rosa Maria Ferraiuolo, Mark J Dunning, Keith F. Stringer, So Won Oh
Publikováno v:
Endocrine-Related Cancer. 26:131-146
Prostate-specific membrane antigen (PSMA) is overexpressed in most prostate adenocarcinoma (AdPC) cells and acts as a target for molecular imaging. However, some case reports indicate that PSMA-targeted imaging could be ineffectual for delineation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b89a9bd5e6e960e0cd6af34b2c8a485
https://doi.org/10.1530/erc-18-0226
https://doi.org/10.1530/erc-18-0226