Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Mark J. Cody"'
Autor:
Claudia V. de Araujo, Frederik Denorme, W. Zac Stephens, Qing Li, Mark J. Cody, Jacob L. Crandell, Aaron C. Petrey, Kimberly A. Queisser, John L. Rustad, James M. Fulcher, Judah L. Evangelista, Michael S. Kay, Joshua D. Schiffman, Robert A. Campbell, Christian C. Yost
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/7d8661c095f542b3a5b93707671c7539
Autor:
Claudia V. de Araujo, Frederik Denorme, W. Zac Stephens, Qing Li, Mark J. Cody, Jacob L. Crandell, Aaron C. Petrey, Kimberly A. Queisser, John L. Rustad, James M. Fulcher, Judah L. Evangelista, Michael S. Kay, Joshua D. Schiffman, Robert A. Campbell, Christian C. Yost
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionNeutrophil extracellular traps (NETs) clear pathogens but may contribute Q8 pathogenically to host inflammatory tissue damage during sepsis. Innovative therapeutic agents targeting NET formation and their potentially harmful collateral ef
Externí odkaz:
https://doaj.org/article/95613aabff2141a381bede33f379a8d5
Autor:
Frederik Denorme, Irina Portier, John L. Rustad, Mark J. Cody, Claudia V. de Araujo, Chieko Hoki, Matthew D. Alexander, Ramesh Grandhi, Mitchell R. Dyer, Matthew D. Neal, Jennifer J. Majersik, Christian C. Yost, Robert A. Campbell
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Ischemic stroke prompts a strong inflammatory response, which is associated with exacerbated outcomes. In this study, we investigated mechanistic regulators of neutrophil extracellular trap (NET) formation in stroke and whether they contribute to str
Externí odkaz:
https://doaj.org/article/7dbf696a51f746e3b12b46ef6daf1b4e
Autor:
Christian C. Yost, Jacob L. Crandell, Robert A. Campbell, J. Samuel Bircher, Heather D. Campbell, John L. Rustad, Yasuhiro Kosaka, Mark J. Cody, Josh Monts, Claudia V. Araujo, Frederik Denorme
Publikováno v:
Blood
Neutrophil extracellular traps (NETs) are important components of innate immunity. Neonatal neutrophils (polymorphonuclear leukocytes [PMNs]) fail to form NETs due to circulating NET-inhibitory peptides (NIPs), cleavage fragments of α1-antitrypsin (
Autor:
Frederik Denorme, John L. Rustad, Irina Portier, Jacob L. Crandell, Claudia V. de Araujo, Mark J. Cody, Robert A. Campbell, Christian C. Yost
Publikováno v:
Pediatric research.
Treatment of neonatal peritonitis and sepsis is challenging. Following infection, neutrophils elaborate neutrophil extracellular traps (NETs)-extracellular lattices of decondensed chromatin decorated with antimicrobial proteins. NETs, however, can au
Autor:
Frederik Denorme, Irina Portier, Mark J Cody, Claudia V De Araujo, John P Rustad, Chieko Hoki, Matthew D Alexander, Ramesh Grandhi, Matthew D Neal, Jennifer J Majersik, Christian C Yost, Robert Campbell
Publikováno v:
Stroke. 53
Rationale: Ischemic stroke prompts an inflammatory response which is associated with worse outcomes. Classic anti-inflammatory strategies were unsuccessful in clinical trials, implying other mechanisms contribute to injurious inflammation in stroke.
Autor:
Robert A. Campbell, Emilia A Tugolukova, Mark J. Cody, Li Guo, Shancy Petsel Jacob, Yasuhiro Kosaka, Ryan M. O'Connell, Frederik Denorme, Bhanu Kanth Manne, Isidore Rigoutsos, Seema Bhatlekar, Paul F. Bray, Jesse W. Rowley
Publikováno v:
Blood Cells Mol Dis
The purpose of this research was to assess the effects of a microRNA (miRNA) cluster on platelet production. Human chromosome 19q13.41 harbors an evolutionarily conserved cluster of three miRNA genes (MIR99B, MIRLET7E, MIR125A) within 727 base-pairs.
Autor:
Charles Langelier, Daniel T. Leung, Paula Hayakawa Serpa, Mark J. Cody, Shubhanshi Trivedi, Christian C. Yost, Taylor A Wahlig, Allie H. Grossmann, Owen Jensen, Kristi J. Warren
Publikováno v:
Open Forum Infectious Diseases
Background Pneumonia and diarrhea are among the leading causes of death worldwide, and epidemiological studies have demonstrated that diarrhea is associated with an increased risk of subsequent pneumonia. Our aim was to determine the impact of intest
Autor:
Shubhanshi Trivedi, Allie H. Grossmann, Owen Jensen, Mark J. Cody, Taylor A. Wahlig, Paula Hayakawa Serpa, Charles Langelier, Kristi J. Warren, Christian C. Yost, Daniel T. Leung
Pneumonia and diarrhea are among the leading causes of death worldwide, and epidemiological studies have demonstrated that diarrhea is associated with an increased risk of subsequent pneumonia. Our aim was to determine the impact of intestinal infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::689b55f0e1c3b12af0973f2e06f7a493
https://doi.org/10.1101/2020.08.03.235457
https://doi.org/10.1101/2020.08.03.235457
Autor:
Elizabeth A. Middleton, Andrew S. Weyrich, Robert A. Campbell, Aaron C. Petrey, Bhanu Kanth Manne, Chris Stubben, Mark J. Cody, Li Guo, Irina Portier, Jesse W. Rowley, Matthew T. Rondina, Frederik Denorme, Neal D. Tolley, Christian C. Yost
Publikováno v:
Blood
There is a Blood Commentary on this article in this issue.
Key Points SARS-CoV-2 induces robust gene expression and functional changes in platelets. Platelet hyperreactivity may contribute to COVID-19 pathophysiology by increased platelet-platel
Key Points SARS-CoV-2 induces robust gene expression and functional changes in platelets. Platelet hyperreactivity may contribute to COVID-19 pathophysiology by increased platelet-platel