Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark J. Aronovitz"'
Autor:
Timothy D. Calamaras, Suchita Pande, Robert A.U. Baumgartner, Seung Kyum Kim, Joseph C. McCarthy, Gregory L. Martin, Kelly Tam, Angela L. McLaughlin, Guang-rong Wang, Mark J. Aronovitz, Weiyu Lin, Jonathan I. Aguirre, Paulina Baca, Peiwen Liu, Daniel A. Richards, Roger J. Davis, Richard H. Karas, Iris Z. Jaffe, Robert M. Blanton
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
cGMP-dependent protein kinase 1α (PKG1α) promotes left ventricle (LV) compensation after pressure overload. PKG1-activating drugs improve heart failure (HF) outcomes but are limited by vasodilation-induced hypotension. Signaling molecules that medi
Externí odkaz:
https://doaj.org/article/5cb3bfd35e8f4781898dd9135f28a00f
Autor:
Jin Zhao, Gavin R Schnitzler, Lakshmanan K Iyer, Mark J Aronovitz, Wendy E Baur, Richard H Karas
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156772 (2016)
MicroRNA-offset RNAs (moRs) were first identified in simple chordates and subsequently in mouse and human cells by deep sequencing of short RNAs. MoRs are derived from sequences located immediately adjacent to microRNAs (miRs) in the primary miR (pri
Externí odkaz:
https://doaj.org/article/cb4e36cc342a4bdc8990daecd21f5750
Autor:
Navin K Kapur, Vikram Paruchuri, Mark J Aronovitz, Xiaoying Qiao, Emily E Mackey, Gerard H Daly, Kishan Ughreja, Jonathan Levine, Robert Blanton, Nicholas S Hill, Richard H Karas
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70802 (2013)
Right ventricular (RV) failure is a major cause of mortality in acute or chronic lung disease and left heart failure. The objective of this study was to demonstrate a percutaneous approach to study biventricular hemodynamics in murine models of prima
Externí odkaz:
https://doaj.org/article/601f03893aa34ae492630ef53ed9ffe1
Autor:
Hongwei Jin, Ho-Jin Park, Mark J Aronovitz, Bo Wang, Yali Zhang, Mark Link, Sami Noujaim, Jonas Galper
Publikováno v:
Circulation. 130
Introduction: Myocardial infarction (MI) is the most common cause of mortality in diabetes. Diabetics have been shown to be twice as likely to die suddenly from MI out of hospital compared to non diabetic patients. The mechanism of sudden death in th
Autor:
Paul J. Wang, F B S James Regan, B S Tim Lenihan, B S Greg Schorn, B S Charles Gilbride, N.A. Mark Estes, Munther K. Homoud, Frederick J. Schoen, Kenneth L. Carr, A B S Brian Vanderbrink, Mark S. Link, Mark J. Aronovitz, B S Kevin Taylor
Publikováno v:
Journal of Cardiovascular Electrophysiology. 11:305-310
Microwave Ablation of Canine Ventricle. Introduction: Radiofrequency current delivered during cardiac ablation is limited by a rise in impedance secondary to coagulum formation on the ablation electrode. Microwave antennas continue to deliver energy
Autor:
Paul J. Wang, Samir Saba, Charles I. Berul, Sita Reddy, Mark J. Aronovitz, David E. Housman, Mark Estes, N.A. Michael E. Mendelsohn M.D., Brenda Luciano, A B S Brian Vanderbrfnk
Publikováno v:
Journal of Cardiovascular Electrophysiology. 10:1214-1220
Heart Block in a Mouse Model of Myotonic Dystrophy. Introduction: A mouse strain lacking functional myotonic dystrophy protein kinase (DMPK) has recently been developed. DMPK-/- mice exhibit muscular and conduction abnormalities consistent with the d
Autor:
Navin K Kapur, Mark J Aronovitz, Robert Blanton, Emily Mackey, Vikram Paruchuri, Xiaoying Qiao, Gerard H Daly, David A Kass, Richard H Karas
Publikováno v:
Circulation Research. 111
Bi-ventricular (Bi-V) function in primary pulmonary hypertension (PPH) or PH secondary to left heart failure (SPH) remains difficult to characterize. As a measure of ventricular efficiency, ventriculo-arterial coupling (VAC) is calculated as the rati
Abstract 1: Opposing Roles for Endoglin and Soluble Endoglin in Cardiac Remodeling and Heart Failure
Autor:
Navin K Kapur, Szuhuei Wilson, Adil A Yunis, Corey Baker, Mark J Aronovitz, Qing Lu, Ananth Karumanchi, Michelle Letarte, David A Kass, Michael E Mendelsohn, Richard H Karas
Publikováno v:
Circulation Research. 109
Transforming growth factor beta-1 (TGFb1) promotes cardiac fibrosis. The transmembrane co-receptor Endoglin (Eng; CD105) facilitates TGFb1 signaling via SMAD effector proteins. In contrast, a circulating form of soluble endoglin (sEng) inhibits TGFb1
Autor:
N.A. Mark Estes, Wei Zhu, Mark J. Aronovitz, Richard H. Karas, Michael E. Mendelsohn, Samir Saba, Paul J. Wang
Publikováno v:
Journal of cardiovascular electrophysiology. 13(3)
Estrogen and Cardiac Electrophysiology.Introduction: Understanding the molecular mechanisms that underlie gender- and hormonal-related differences in susceptibility to cardiac arrhythmias has been hampered by the lack of a suitable animal model. We e