Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Mark J van Raaij"'
Autor:
Mohammad Z Islam, Andrei Fokine, Marthandan Mahalingam, Zhihong Zhang, Carmela Garcia-Doval, Mark J van Raaij, Michael G Rossmann, Venigalla B Rao
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008193 (2019)
Tailed bacteriophages (phages) are one of the most abundant life forms on Earth. They encode highly efficient molecular machines to infect bacteria, but the initial interactions between a phage and a bacterium that then lead to irreversible virus att
Externí odkaz:
https://doaj.org/article/072379ea141341dfa845bd1675c95bff
Autor:
Lara González‐Cabaleiro, Carlos Fernández‐Lodeiro, Lorena Vázquez‐Iglesias, Pablo Soriano‐Maldonado, Mark J. van Raaij, Gustavo Bodelón, Jorge Pérez‐Juste, Isabel Pastoriza‐Santos
Publikováno v:
Small Science, Vol 4, Iss 11, Pp n/a-n/a (2024)
Lateral flow immunoassays (LFIAs) are easy‐to‐use antigen tests that provide different signal readouts, with colorimetric readouts being the most commonly used. However, these analytical devices have relatively low sensitivity and produce semiqua
Externí odkaz:
https://doaj.org/article/489cfb48c91a4632957cf307abe3731c
Autor:
Abhimanyu K Singh, M Álvaro Berbís, Mónika Z Ballmann, Michelle Kilcoyne, Margarita Menéndez, Thanh H Nguyen, Lokesh Joshi, F Javier Cañada, Jesús Jiménez-Barbero, Mária Benkő, Balázs Harrach, Mark J van Raaij
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139339 (2015)
The virulent form of turkey adenovirus 3 (TAdV-3), also known as turkey hemorrhagic enteritis virus (THEV), is an economically important poultry pathogen, while the avirulent form is used as a vaccine. TAdV-3 belongs to the genus Siadenovirus. The ca
Externí odkaz:
https://doaj.org/article/a156d06cf845405b86d97a4de08aa685
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114373 (2014)
Adenoviruses are non-enveloped icosahedral viruses with trimeric fibre proteins protruding from their vertices. There are five known genera, from which only Mastadenoviruses have been widely studied. Apart from studying adenovirus as a biological mod
Externí odkaz:
https://doaj.org/article/8b005e3e357a456d908ef745075bf122
Autor:
Abrar Senhaji-Kacha, Mireia Bernabéu-Gimeno, Pilar Domingo-Calap, John Jairo Aguilera-Correa, Mateo Seoane-Blanco, Sara Otaegi-Ugartemendia, Mark J. van Raaij, Jaime Esteban, Meritxell García-Quintanilla
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The increase of antibiotic-resistant bacteria has become a global health emergency and the need to explore alternative therapeutic options arises. Phage therapy uses bacteriophages to target specific bacterial strains. Phages are highly specific and
Externí odkaz:
https://doaj.org/article/8c11897a0c9c42599b584b763b015bb2
Publikováno v:
IUCrJ, Vol 10, Iss 4, Pp 377-379 (2023)
This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.
Externí odkaz:
https://doaj.org/article/08110045186d4245962bb14f4413bfb6
Autor:
Ángela Rodríguez, María Maneiro, Emilio Lence, José M. Otero, Mark J. van Raaij, Paul Thompson, Alastair R. Hawkins, Concepción González-Bello
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Irreversible inhibition of the enzyme type I dehydroquinase (DHQ1), a promising target for anti-virulence drug development, has been explored by enhancing the electrophilicity of specific positions of the ligand towards covalent lysine modification.
Externí odkaz:
https://doaj.org/article/cd7d202952bc4340a777bcf1a88518ac
Autor:
Carmen San Martín, Mark J. van Raaij
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-6 (2018)
Abstract Background During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until
Externí odkaz:
https://doaj.org/article/0ab464e9f3e14a6e95a94274da76e881
Autor:
Cristina Di Carluccio, Pablo Soriano-Maldonado, Francesca Berni, Carla J. C. de Haas, A. Robin Temming, Astrid Hendriks, Sara Ali, Antonio Molinaro, Alba Silipo, Nina M. van Sorge, Mark J. van Raaij, Jeroen D. C. Codee, Roberta Marchetti
Publikováno v:
ACS central science, 8(10), 1383-1392. American Chemical Society
ACS Central Science, 8(10), 1383-1392. AMER CHEMICAL SOC
ACS Central Science, 8(10), 1383-1392. AMER CHEMICAL SOC
Wall teichoic acids (WTAs) are glycopolymers decorating the surface of Gram-positive bacteria and potential targets for antibody-mediated treatments against Staphylococcus aureus, including methicillin-resistant (MRSA) strains. Through a combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4534148026eee302ec05fb1a9076575
http://www.scopus.com/inward/record.url?scp=85136686120&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85136686120&partnerID=8YFLogxK
Autor:
Roberto Vázquez, Mateo Seoane-Blanco, Virginia Rivero-Buceta, Susana Ruiz, Mark J. van Raaij, Pedro García
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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20 p.-11 fig.-1 tab.
Phage lysins are a source of novel antimicrobials to tackle the bacterial antibiotic-resistance crisis. The engineering of phage lysins is being explored as a game-changing technological strategy to introduce a more precise
Phage lysins are a source of novel antimicrobials to tackle the bacterial antibiotic-resistance crisis. The engineering of phage lysins is being explored as a game-changing technological strategy to introduce a more precise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810f26d8d384510afd7859b3e28ba2e8
http://hdl.handle.net/10261/266361
http://hdl.handle.net/10261/266361
