Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Mark J Shlomchik"'
Autor:
Mark J Shlomchik, Claire Leibler, Shinu John, Shuchi Smita, Rachael Gordon, Sebastien Gingras, Sheldon Bastacky, Kensuke Miyake, Rebecca A Elsner, Kayla B Thomas, Stephen Joachim, Russell C Levack, Derrick Callahan, Ryutaro Fukui, Kevin M Nickerson
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/7e866731d48b4a219781ba0c08e5ac84
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/16a3635a5e904b7eacfb6a8bc89b58fe
Autor:
Mark J Shlomchik, Jeremy Tilstra, Claire Leibler, Shinu John, Kayla Thomas, Shuchi Smita, Rachael Gordon, Sebastien Gingras, Sheldon Bastacky, Kevin Nickerson
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/ef5c1f2c803245258c493e45c352c84a
Autor:
Rachael A Gordon, Jeremy S Tilstra, Anthony Marinov, Kevin M Nickerson, Sheldon I Bastacky, Mark J Shlomchik
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0226396 (2020)
Loss of tolerance to nuclear antigens and multisystem tissue destruction is a hallmark of systemic lupus erythematosus (SLE). Although the source of autoantigen in lupus remains elusive, a compelling hypothetical source is dead cell debris that drive
Externí odkaz:
https://doaj.org/article/85e463fd0b2544e280c52de750b2e124
Autor:
David S Nelson, Ryan L Marano, Yechaan Joo, Sara Y Tian, Bhumi Patel, Daniel H Kaplan, Mark J Shlomchik, Kristen Stevenson, Roderick T Bronson, Barrett J Rollins
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222400 (2019)
Langerhans cell histiocytosis (LCH) is characterized by the accumulation of Langerin (CD207)-expressing histiocytes. Mutational activation of mitogen-activated protein kinase pathway genes, in particular BRAF, drives most cases. To test whether activ
Externí odkaz:
https://doaj.org/article/558463d275d0429ebb07e2d707219cea
Autor:
Chelsea R Parker Harp, Angela S Archambault, Julia Sim, Mark J Shlomchik, John H Russell, Gregory F Wu
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199694 (2018)
Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune encephalomyelitis (EAE), a murine model of M
Externí odkaz:
https://doaj.org/article/485ded0f63a5431fb7b38915fa92e06c
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173471 (2017)
Genetic deficiency in TLR9 accelerates pathogenesis in the spontaneous polygenic MRL.Faslpr murine model of systemic lupus erythematosus, despite the absence of anti-nucleosome autoantibodies. However, it could be argued that this result was dependen
Externí odkaz:
https://doaj.org/article/0b865c572e30400189c2ed5a59120094
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92009 (2014)
CD73 catalyzes the conversion of extracellular nucleosides to adenosine, modulating inflammatory and T cell responses. Elevated expression of CD73 marks subpopulations of murine memory B cells (MBC), but its role in memory development or function is
Externí odkaz:
https://doaj.org/article/cb8bb286e44442008442e0b00589cc32
Autor:
Kevin M. Nickerson, Shuchi Smita, Kenneth B. Hoehn, Anthony D. Marinov, Kayla B. Thomas, Justin T. Kos, Yi Yang, Sheldon I. Bastacky, Corey T. Watson, Steven H. Kleinstein, Mark J. Shlomchik
Publikováno v:
Journal of Experimental Medicine. 220
Age-associated B cells (ABCs) are formed under inflammatory conditions and are considered a type of memory B cell (MBC) expressing the transcription factor T-bet. In SLE, ABC frequency is correlated with disease, and they are thought to be the source
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31f4cf0433df6f2565b6ee8acd6a8f47
https://doi.org/10.1084/jem.20221346
https://doi.org/10.1084/jem.20221346
Autor:
Nadine M. Weisel, Stephen M. Joachim, Shuchi Smita, Derrick Callahan, Rebecca A. Elsner, Laura J. Conter, Maria Chikina, Donna L. Farber, Florian J. Weisel, Mark J. Shlomchik
Publikováno v:
Nat Immunol
Memory B cells (MBC) protect the body from recurring infections. MBC differ from their naïve counterparts in many ways, but functional and surface marker differences are poorly characterized. In addition, though mice are the prevalent model for huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16771fe666768b68946583a0151c02a
https://doi.org/10.1038/s41590-021-01078-x
https://doi.org/10.1038/s41590-021-01078-x