Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Mark J Prescott"'
Publikováno v:
F1000Research, Vol 11 (2023)
Background: Accurate assessment of the welfare of non-human primates (NHPs) used and bred for scientific purposes is essential for effective implementation of obligations to optimise their well-being, for validation of refinement techniques and novel
Externí odkaz:
https://doaj.org/article/1aa122b495f540f68963b63be6a40064
Autor:
Lauren Young, Donna Goldsteen, Elizabeth A Nunamaker, Mark J Prescott, Penny Reynolds, Sally Thompson-Iritani, Sarah E Thurston, Tara L Martin, Megan R LaFollette
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0288010 (2023)
Refined handling improves laboratory mouse welfare and research outcomes when compared to traditional tail handling, yet implementation does not seem to be widespread. Refined handling includes picking up a mouse using a tunnel or cupped hands. The a
Externí odkaz:
https://doaj.org/article/246549f9562c45c9815019fc50d50720
Publikováno v:
F1000Research, Vol 11 (2022)
Background: Accurate assessment of the welfare of non-human primates (NHPs) used and bred for scientific purposes is essential for effective implementation of obligations to optimise their well-being, for validation of refinement techniques and novel
Externí odkaz:
https://doaj.org/article/ea16d4a826304438931ebbf743b82331
Autor:
Mark J. Prescott, Colline Poirier
Publikováno v:
NeuroImage, Vol 225, Iss , Pp 117521- (2021)
Magnetic resonance imaging is playing a significant role in applying the 3Rs to neuroscience studies using non-human primates. MRI scans are contributing to refinement by enhancing the selection and assignment of animals, guiding the manufacture of c
Externí odkaz:
https://doaj.org/article/8d5961336ee041e5a8fbdc7fe667f1c4
Publikováno v:
Vaccines, Vol 9, Iss 3, p 284 (2021)
Non-human primates (NHPs) are used extensively in the development of vaccines and therapeutics for human disease. High standards in the design, conduct, and reporting of NHP vaccine studies are crucial for maximizing their scientific value and transl
Externí odkaz:
https://doaj.org/article/288a9bad15274de9b1d701e21dafe79d
Autor:
Mark J. Prescott
Publikováno v:
Journal of applied animal ethics research
Breakthroughs in gene editing technologies have made it feasible to create genetically altered (GA) non-human primate (NHP) models of disease. This area of research is accelerating, particularly in China, Japan and the USA, and could lead to an incre
Autor:
Chris Barkus, Caroline Bergmann, Tiago Branco, Matteo Carandini, Paul T. Chadderton, Gregorio L. Galiñanes, Gary Gilmour, Daniel Huber, John R. Huxter, Adil G. Khan, Andrew J. King, Miguel Maravall, Tina O’Mahony, C. Ian Ragan, Emma S.J. Robinson, Andreas T. Schaefer, Simon R. Schultz, Frank Sengpiel, Mark J. Prescott
Publikováno v:
Journal of Neuroscience Methods. 381:109705
The use of head fixation in mice is increasingly common in research, its use having initially been restricted to the field of sensory neuroscience. Head restraint has often been combined with fluid control, rather than food restriction, to motivate b
Autor:
Laura Scullion Hall, Mark J. Prescott
Publikováno v:
Behavioral Biology of Laboratory Animals ISBN: 9780429019517
Behavioral Biology of Laboratory Animals
Behavioral Biology of Laboratory Animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::105e65932e0ef6035997c64760416713
https://doi.org/10.1201/9780429019517-15
https://doi.org/10.1201/9780429019517-15
Autor:
Mark J. Prescott
Publikováno v:
Advances in science and research
Advances in Science and Research, Vol 5, Pp 11-22 (2010)
Advances in Science and Research, Vol 5, Pp 11-22 (2010)
This article provides an overview of the ethical issues raised by the use of non-human primates (NHPs) in research involving scientific procedures which may cause pain, suffering, distress or lasting harm. It is not an exhaustive review of the litera
Autor:
Colline Poirier, Mark J. Prescott
Publikováno v:
NeuroImage, Vol 225, Iss, Pp 117521-(2021)
Magnetic resonance imaging is playing a significant role in applying the 3Rs to neuroscience studies using non-human primates. MRI scans are contributing to refinement by enhancing the selection and assignment of animals, guiding the manufacture of c