Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mark J Mondrinos"'
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195379 (2018)
Sepsis is characterized by an intense systemic inflammatory response activating a cascade of proinflammatory events resulting in leukocyte dysregulation and host tissue damage. The lung is particularly susceptible to systemic inflammation, leading to
Externí odkaz:
https://doaj.org/article/fc9efd8e9e0043b784230d3bf81524b3
Autor:
Khoa Nguyen, Hassan Yousefi, Thomas Cheng, Justin Magrath, Alifiani B. Hartono, Madlin Alzoubi, Katherine Hebert, Courtney K. Brock, Maryl K. Wright, Charles Ethan Byrne, Andrew Rivera, Sam C. Okpechi, Margarite Delores Matossian, Henri Wathieu, Steven Elliott, Mark J. Mondrinos, Sean B. Lee, Bridgette M. Collins-Burow, Suresh K. Alahari, David H. Drewry, Matthew E. Burow
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 6, p 196 (2022)
Mitogen Activated Protein (MAP) kinases are a category of serine/threonine kinases that have been demonstrated to regulate intracellular events including stress responses, developmental processes, and cancer progression Although many MAP kinases have
Externí odkaz:
https://doaj.org/article/f1e52c65eb234aa198f9f900ec5bafe0
Autor:
Matthew E. Burow, David H. Drewry, Suresh K. Alahari, Bridgette M. Collins-Burow, Sean B. Lee, Mark J. Mondrinos, Steven Elliott, Henri Wathieu, Margarite Delores Matossian, Sam C. Okpechi, Andrew Rivera, Charles Ethan Byrne, Maryl K. Wright, Courtney K. Brock, Katherine Hebert, Madlin Alzoubi, Alifiani B. Hartono, Justin Magrath, Thomas Cheng, Hassan Yousefi, Khoa Nguyen
Publikováno v:
Frontiers in bioscience (Landmark edition). 27(6)
Mitogen Activated Protein (MAP) kinases are a category of serine/threonine kinases that have been demonstrated to regulate intracellular events including stress responses, developmental processes, and cancer progression Although many MAP kinases have
Autor:
Sun Min Kim, Cassidy Blundell, Dongeun Huh, Tae-Joon Jeon, Matthew J. Osborn, Farid Alisafaei, Insu Lee, Vivek B. Shenoy, Mark J. Mondrinos, Jeongyun Seo, Hossein Ahmadzadeh, Alex Y. Yi
Publikováno v:
Science Advances
A developmentally inspired tissue engineering method enables the construction of microphysiological musculoskeletal tissue models.
Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile c
Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile c
Autor:
William K. Cornwell, Çagla Tükel, Thomas J. Rogers, Shuang Sun, Elisabetta Liverani, Mark J. Mondrinos, Laurie E. Kilpatrick, Marla R. Wolfson, Sarah A. Tursi, Bettina A. Buttaro
Publikováno v:
FASEB J
Sepsis is a leading cause of morbidity and mortality in intensive care units. Previously, we identified Protein Kinase C-delta (PKCδ) as an important regulator of the inflammatory response in sepsis. An important issue in development of anti-inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95eb8c4932d1984917a5b3105ffe756
https://europepmc.org/articles/PMC7568544/
https://europepmc.org/articles/PMC7568544/
Autor:
Ernesto Goulart, Peter I. Lelkes, Collin T. Stabler, Mark J. Mondrinos, Shimon Lecht, Philip Lazarovici
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 309:L1273-L1285
There is a clear unmet clinical need for novel biotechnology-based therapeutic approaches to lung repair and/or replacement, such as tissue engineering of whole bioengineered lungs. Recent studies have demonstrated the feasibility of decellularizing
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0195379 (2018)
PLoS ONE, Vol 13, Iss 4, p e0195379 (2018)
Sepsis is characterized by an intense systemic inflammatory response activating a cascade of proinflammatory events resulting in leukocyte dysregulation and host tissue damage. The lung is particularly susceptible to systemic inflammation, leading to
Autor:
Matthew Kauffman, Paul A. Kennedy, Jichuan Wu, Linda C. Knight, Sandy T. Baker, Marla R. Wolfson, Laurie E. Kilpatrick, Mark J. Mondrinos
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 355:86-98
Sepsis and sepsis-induced lung injury remain a leading cause of death in intensive care units. We identified protein kinase C-δ (PKCδ) as a critical regulator of the acute inflammatory response and demonstrated that PKCδ inhibition was lung-protec
Autor:
Michael Frohbergh, Peter I. Lelkes, Kurt D. Hankenson, Mark J. Mondrinos, Collin T. Stabler, Jeffrey T. Oristaglio, Anya Katsman
Publikováno v:
Tissue Engineering Part A. 21:970-981
Our long-term goal is to develop smart biomaterials that can facilitate regeneration of critical-size craniofacial lesions. In this study, we tested the hypothesis that biomimetic scaffolds electrospun from chitosan (CTS) will promote tissue repair a
Publikováno v:
Lab on a chip. 17(18)
Semipermeable cell culture membranes are commonly used in multilayered microfluidic devices to mimic the basement membrane in vivo and to create compartmentalized microenvironments for physiological cell growth and differentiation. However, existing