Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Mark J Graham"'
Autor:
Robert N Helsley, Venkateshwari Varadharajan, Amanda L Brown, Anthony D Gromovsky, Rebecca C Schugar, Iyappan Ramachandiran, Kevin Fung, Mohammad Nasser Kabbany, Rakhee Banerjee, Chase K Neumann, Chelsea Finney, Preeti Pathak, Danny Orabi, Lucas J Osborn, William Massey, Renliang Zhang, Anagha Kadam, Brian E Sansbury, Calvin Pan, Jessica Sacks, Richard G Lee, Rosanne M Crooke, Mark J Graham, Madeleine E Lemieux, Valentin Gogonea, John P Kirwan, Daniela S Allende, Mete Civelek, Paul L Fox, Lawrence L Rudel, Aldons J Lusis, Matthew Spite, J Mark Brown
Publikováno v:
eLife, Vol 8 (2019)
Recent studies have identified a genetic variant rs641738 near two genes encoding membrane bound O-acyltransferase domain-containing 7 (MBOAT7) and transmembrane channel-like 4 (TMC4) that associate with increased risk of non-alcoholic fatty liver di
Externí odkaz:
https://doaj.org/article/f9448bea0b9e426ea0147da3a9110b3e
Autor:
Seonwook Kim, Lihua Yang, Seongu Kim, Richard G Lee, Mark J Graham, Judith A Berliner, Aldons J Lusis, Lei Cai, Ryan E Temel, Debra L Rateri, Sangderk Lee
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182566 (2017)
OBJECTIVE:The upregulated expression of heparin binding EGF-like growth factor (HB-EGF) in the vessel and circulation is associated with risk of cardiovascular disease. In this study, we tested the effects of HB-EGF targeting using HB-EGF-specific an
Externí odkaz:
https://doaj.org/article/7a01c34609f145269ae670b9c9d0e7fe
Autor:
David Hanauer, Richard Alvey, Ping An, Christa Bancroft, Kristen Butela, Sean Coleman, Kari L. Clase, Parks Collins, Stephanie Conant, Pamela Connerly, Bernadette Connors, Megan K. Dennis, Erin L. Doyle, Dustin Edwards, Christy Fillman, Ann Findley, Victoria J. Frost, Maria Gainey, Urszula Golebiewska, Nancy Guild, Sharon B. Gusky, Allison Johnson, Kristen Johnson, Karen K. Klyczek, Julia Lee-Soety, Heather Lindberg, Matthew D. Mastropaolo, Julie A. Merkle, Jon Mitchell, Sally Molloy, Fernando Nieto, Jillian Nissen, Tiara Perez Morales, Nick T. Peters, Susanne P. Pfeifer, Richard Pollenz, Mary L. Preuss, Germán Rosas-Acosta, Margaret S. Saha, Amy Sprenkle, C. Nicole Sunnen, Deborah Tobiason, Sara S. Tolsma, Vassie Ware, Yesmi Patricia Ahumada-Santos, Regina V. Alvarez, Justin Anderson, Mary Ayuk, María Elena Báez-Flores, Dondra Bailey, Frederick Baliraine, Elizabeth Behr, Andrea R. Beyer, Suparna Bhalla, Lisa M. Bono, Donald P. Breakwell, Christine Byrum, Iain Duffy, Alyssa Gleichsner, Melinda Harrison, Renee Ho, Lee E. Hughes, Jacob D. Kagey, Kathryn Kohl, Sean McClory, Alison Moyer, Maria A. Mussi, Holly Nance, Imade Y. Nsa, Shallee T. Page, Jesús Ricardo Parra Unda, Jessica Rocheleau, Sarah Swerdlow, Kara Thoemke, Megan S. Valentine, Quinn C. Vega, Catherine Ward, Daniel C. Williams, Ellen Wisner, William H. Biederman, Steven G. Cresawn, Mark J. Graham, Graham Hatfull, Danielle Heller, Deborah Jacobs-Sera, Denise Monti, Pushpa Ramakrishna, Daniel Russell, Viknesh Sivanathan
Publikováno v:
Frontiers in Education, Vol 9 (2024)
The professional identity of scientists has historically been cultivated to value research over teaching, which can undermine initiatives that aim to reform science education. Course-Based Research Experiences (CRE) and the inclusive Research and Edu
Externí odkaz:
https://doaj.org/article/21dd741f0857420e8bbeab64c35a9637
Autor:
Denise L. Monti, Julia C. Gill, Tamarah L. Adair, Sandra D. Adams, Yesmi Patricia Ahumada-Santos, Isabel Amaya, Kirk Anders, Justin R. Anderson, Mauricio S. Antunes, Mary Ayuk, Frederick Baliraine, Tonya C. Bates, Andrea R. Beyer, Suparna Bhalla, Tejas Bouklas, Sharon K. Bullock, Kristen A. Butela, Christine Byrum, Steven M. Caruso, Rebecca Chong, Hui-Min Chung, Stephanie B. Conant, Brett Condon, Katie E. Crump, Tom D'Elia, Megan K. Dennis, Linda C. DeVeaux, Lautaro Diacovich, Arturo Diaz, Iain Duffy, Dustin Edwards, Patricia C. Fallest-Strobl, Ann Findley, Matthew R. Fisher, Marie P. Fogarty, Victoria Jane Frost, Maria D. Gainey, Courtney S. Galle, Bryan Gibb, Urszula Golebiewska, Hugo Gramajo, Anna S. Grinath, Jennifer Guerrero, Nancy Guild, Kathryn E. Gunn, Susan Gurney, Lee E. Hughes, Pradeepa Jayachandran, Kristen Johnson, Allison Johnson, Alison E. Kanak, Michelle L. Kanther, Rodney A. King, Kathryn Kohl, Julia Lee-Soety, Lynn O. Lewis, Heather Lindberg, Jaclyn A. Madden, Breonna J. Martin, Matthew D. Mastropaolo, Sean McClory, Evan C. Merkhofer, Julie A. Merkle, Jon Mitchell, María Alejandra Mussi, Fernando Nieto, Jillian Nissen, Imade Yolanda Nsa, Mary G. O'Donnell, R. Deborah Overath, Shallee T. Page, Andrea Panagakis, Jesús Ricardo Parra Unda, Michelle B. Pass, Tiara Perez Morales, Nick T. Peters, Ruth Plymale, Richard Pollenz, Nathan S. Reyna, Claire A. Rinehart, Jessica Rocheleau, John S. Rombold, Ombeline Rossier, Adam D. Rudner, Elizabeth E. Rueschhoff, Christopher D. Shaffer, Mary Ann V. Smith, Amy B. Sprenkle, C. Nicole Sunnen, Michael A. Thomas, Michelle M. Tigges, Deborah Tobiason, Sara Sybesma Tolsma, Julie Torruellas Garcia, Peter Uetz, Edwin Vazquez, Catherine M. Ward, Vassie C. Ware, Jacqueline M. Washington, Matthew J. Waterman, Daniel E. Westholm, Keith A. Wheaton, Simon J. White, Elizabeth C. Williams, Daniel C. Williams, Ellen M. Wisner, William H. Biederman, Steven G. Cresawn, Danielle M. Heller, Deborah Jacobs-Sera, Daniel A. Russell, Graham F. Hatfull, David J. Asai, David I. Hanauer, Mark J. Graham, Viknesh Sivanathan
Publikováno v:
Frontiers in Education, Vol 9 (2024)
Over the last two decades, there have been numerous initiatives to improve undergraduate student outcomes in STEM. One model for scalable reform is the inclusive Research Education Community (iREC). In an iREC, STEM faculty from colleges and universi
Externí odkaz:
https://doaj.org/article/f50dca97413047c5972e7d31f6d2f587
Autor:
Rosie Z Yu, Mark J Graham, Noah Post, Stan Riney, Thomas Zanardi, Shannon Hall, Jennifer Burkey, Colby S Shemesh, Thazha P Prakash, Punit P Seth, Eric E Swayze, Richard S Geary, Yanfeng Wang, Scott Henry
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Triantennary N-acetyl galactosamine (GalNAc3)-conjugated antisense oligonucleotides (ASOs) have greatly improved potency via receptor-mediated uptake. In the present study, the in vivo pharmacology of a 2′-O-(2-methoxyethyl)-modified ASO conjugated
Externí odkaz:
https://doaj.org/article/2b26807b841244429f7ffc38c01b9c47
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Preclinical and clinical data suggest CD40 activation contributes to renal inflammation and injury. We sought to test whether upregulation of CD40 in the kidney is a causative factor of renal pathology and if reduction of renal CD40 expression, using
Externí odkaz:
https://doaj.org/article/7d580cead0ee4bb8bf6901d073fb5063
Autor:
Stephanie M Marshall, Kathryn L Kelley, Matthew A Davis, Martha D Wilson, Allison L McDaniel, Richard G Lee, Rosanne M Crooke, Mark J Graham, Lawrence L Rudel, J Mark Brown, Ryan E Temel
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84418 (2014)
An effective way to reduce LDL cholesterol, the primary risk factor of atherosclerotic cardiovascular disease, is to increase cholesterol excretion from the body. Our group and others have recently found that cholesterol excretion can be facilitated
Externí odkaz:
https://doaj.org/article/1257b92d3ba44f13a41a71e33d050372
Autor:
Stephanie M Marshall, Anthony D Gromovsky, Kathryn L Kelley, Matthew A Davis, Martha D Wilson, Richard G Lee, Rosanne M Crooke, Mark J Graham, Lawrence L Rudel, J Mark Brown, Ryan E Temel
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98953 (2014)
The primary risk factor for atherosclerotic cardiovascular disease is LDL cholesterol, which can be reduced by increasing cholesterol excretion from the body. Fecal cholesterol excretion can be driven by a hepatobiliary as well as a non-biliary pathw
Externí odkaz:
https://doaj.org/article/86f8bd2c2f1d4a9396001c438bdfade9
Autor:
Nicholas R Jones, Melissa A Pegues, Mark A McCrory, Walter Singleton, Claudette Bethune, Brenda F Baker, Daniel A Norris, Rosanne M Crooke, Mark J Graham, Alexander J Szalai
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Observational studies of patients with established rheumatoid arthritis (RA) document a positive correlation between C-reactive protein (CRP) blood concentration and worsening of RA symptoms, but whether this association is causal or not is not known
Externí odkaz:
https://doaj.org/article/392f92544a1e404c948aadef7b9151a7
Autor:
Melanie Vincent, Naomi L Sayre, Mark J Graham, Rosanne M Crooke, David J Shealy, Laura Liscum
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12941 (2010)
Niemann-Pick type C (NPC) disease is a lysosomal storage disease characterized by the accumulation of cholesterol and glycosphingolipids. The majority of NPC patients die in their teen years due to progressive neurodegeneration; however, half of NPC
Externí odkaz:
https://doaj.org/article/5a268db0d5ab4baea643bd72f55fdf0a