Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark J Bigland"'
Autor:
Lucy A. Murtha, Sean A. Hardy, Nishani S. Mabotuwana, Mark J. Bigland, Taleah Bailey, Kalyan Raguram, Saifei Liu, Doan T. Ngo, Aaron L. Sverdlov, Tamara Tomin, Ruth Birner-Gruenberger, Robert D. Hume, Siiri E. Iismaa, David T. Humphreys, Ralph Patrick, James J. H. Chong, Randall J. Lee, Richard P. Harvey, Robert M. Graham, Peter P. Rainer, Andrew J. Boyle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role in the heart is unknown. We have demo
Externí odkaz:
https://doaj.org/article/a7e2f43b7c7844a0a23cc1ccd8d00927
Autor:
Lauren A Poppi, Mark J Bigland, Ethan T Cresswell, Hessam Tabatabaee, David Lorincz, Hannah R Drury, Robert J Callister, Joseph C Holt, Rebecca Lim, Alan M Brichta, Doug W Smith
Publikováno v:
The Journals of Gerontology: Series A.
Cholinergic circuits in the central nervous system are vulnerable to age-related functional decline, but it is not known if aging impacts cholinergic signaling in the vestibular sensory organs, which are critically important to balance maintenance an
Autor:
Patricia T. Michie, Paul A. Tooney, Mark J. Bigland, Ryan J. Duchatel, Deborah M. Hodgson, Lauren Harms, Crystal L. Meehan, Doug W. Smith, Phillip Jobling, Frederick R. Walker
Publikováno v:
Psychiatry Research. 266:175-185
Animal models of maternal immune activation study the effects of infection, an environmental risk factor for schizophrenia, on brain development. Microglia activation and cytokine upregulation may have key roles in schizophrenia neuropathology. We hy
Autor:
Andrew J. Boyle, Mark J. Bigland
Publikováno v:
Journal of the American College of Cardiology. 75:1036
Publikováno v:
Current Aging Science
Background Deterioration in vestibular function occurs with ageing and is linked to age-related falls. Sensory hair cells located in the inner ear vestibular labyrinth are critical to vestibular function. Vestibular hair cells rely predominantly on o
Autor:
Lauren Harms, Phillip Jobling, Mark J. Bigland, Ryan J. Duchatel, Patricia T. Michie, Deborah M. Hodgson, Crystal L. Meehan, Doug W. Smith, Paul A. Tooney
Publikováno v:
Schizophrenia research. 199
Publikováno v:
The Spine Journal. 15:1310-1317
Background context One theory within chiropractic proposes that vertebral subluxation in the upper cervical region induces spinal cord compression sufficient to alter spinal cord efferent output. We report on the feasibility of three different experi
Autor:
Daniel J. McIlroy, Mark J. Bigland, Amanda E. White, Doug W. Smith, Zsolt J. Balogh, Benjamin M. Hardy, Natalie Lott
Publikováno v:
The Journal of Trauma and Acute Care Surgery
Supplemental digital content is available in the text.
BACKGROUND Mitochondrial DNA (mtDNA), a potent proinflammatory damage-associated molecular pattern, is released in large titers following trauma. The effect of trauma surgery on mtDNA concen
BACKGROUND Mitochondrial DNA (mtDNA), a potent proinflammatory damage-associated molecular pattern, is released in large titers following trauma. The effect of trauma surgery on mtDNA concen
Autor:
Ryan J. Duchatel, Crystal L. Meehan, Doug W. Smith, Deborah M. Hodgson, Lauren Harms, Phillip Jobling, Paul A. Tooney, Mark J. Bigland, Patricia T. Michie
Publikováno v:
Psychiatry Research. 282:112621
Alterations in GABAergic interneurons and glutamic acid decarboxylase (GAD) are observed in the brains of people with schizophrenia. Studies also show increased density of interstitial white matter neurons (IWMN), including those containing GAD and s