Zobrazeno 1 - 10
of 374
pro vyhledávání: '"Mark J, Siedner"'
Autor:
Karla I. Galaviz, Shivani A. Patel, Mark J. Siedner, Charles W. Goss, Siphamandla B. Gumede, Leslie C. Johnson, Claudia E. Ordóñez, Michael Laxy, Kerstin Klipstein-Grobusch, Martin Heine, Mary Masterson, Aaloke Mody, W. D. Francois Venter, Vincent C. Marconi, Mohammed K. Ali, Samanta T. Lalla-Edward
Publikováno v:
Implementation Science Communications, Vol 5, Iss 1, Pp 1-11 (2024)
Abstract Background HIV clinical guidelines recommend hypertension detection and management to lower cardiovascular disease risk, but these have not been effectively implemented for people living with HIV (PWH). Addressing this implementation gap req
Externí odkaz:
https://doaj.org/article/6500f9a41cf5413da0e7c433f599c97a
Autor:
Leslie C. M. Johnson, Suha H. Khan, Mohammed K. Ali, Karla I. Galaviz, Fatima Waseem, Claudia E. Ordóñez, Mark J. Siedner, Athini Nyatela, Vincent C. Marconi, Samanta T. Lalla-Edward
Publikováno v:
Implementation Science Communications, Vol 5, Iss 1, Pp 1-13 (2024)
Abstract Background The burden of hypertension among people with HIV is high, particularly in low-and middle-income countries, yet gaps in hypertension screening and care in these settings persist. This study aimed to identify facilitators of and bar
Externí odkaz:
https://doaj.org/article/7972c0f49c98416da51f46cb8bb79aea
Autor:
Alison C. Castle, Yumna Moosa, Helgard Claassen, Sheela Shenoi, Itai Magodoro, Jennifer Manne-Goehler, Willem Hanekom, Ingrid V. Bassett, Emily B. Wong, Mark J. Siedner
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Growing evidence suggests that chronic inflammation caused by tuberculosis (TB) may increase the incidence of diabetes. However, the relationship between post-TB pulmonary abnormalities and diabetes has not been well characterized
Externí odkaz:
https://doaj.org/article/08bed2ea5cfa4056a109ccbaa4fb65cc
Autor:
Itai M. Magodoro, Carlos E. Guerrero-Chalela, Brian Claggett, Stephen Jermy, Petronella Samuels, Landon Myer, Heather J Zar, Jennifer Jao, Mpiko Ntsekhe, Mark J. Siedner, Ntobeko A. B. Ntusi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Whether, and how, cardioprotective effects of antiretroviral treatment (ART) in adolescents with perinatal HIV infection (APHIV) vary with age at treatment initiation is unknown. We used magnetic resonance imaging to compare cardiac status b
Externí odkaz:
https://doaj.org/article/ab1f316a90cc45019793de3a13b65abd
Associations of HIV and prevalent type 2 diabetes mellitus in the context of obesity in South Africa
Autor:
Itai M Magodoro, Alison C Castle, Ndumiso Tshuma, Julia H Goedecke, Ronel Sewpaul, Justen Manasa, Jennifer Manne-Goehler, Ntobeko AB Ntusi, Moffat J Nyirenda, Mark J Siedner
Publikováno v:
Journal of Multimorbidity and Comorbidity, Vol 14 (2024)
Background It is unclear how rising obesity among people with HIV (PWH) impacts their risk of type 2 diabetes mellitus (diabetes). We examined associations between HIV, prevalent diabetes and adiposity among South African PWH and their peers without
Externí odkaz:
https://doaj.org/article/ff91a869d5ec4b94bedd876516f7f5e6
Autor:
Lisa M. Bebell, Joseph Ngonzi, Audrey Butler, Elias Kumbakumba, Julian Adong, Carolin Loos, Adeline A. Boatin, Ingrid V. Bassett, Mark J. Siedner, Paige L. Williams, Heather Mattie, Bethany Hedt-Gauthier, Katharine F. B. Correia, Erin Lake, Galit Alter
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract During pregnancy, multiple immune regulatory mechanisms establish an immune-tolerant environment for the allogeneic fetus, including cellular signals called cytokines that modify immune responses. However, the impact of maternal HIV infectio
Externí odkaz:
https://doaj.org/article/1fc2d84db2234d0ea12427ba832bbd11
Autor:
Steven A. Kemp, Kimia Kamelian, Diego F. Cuadros, PANGEA Consortium, Vukuzazi Team, Mark T. K. Cheng, Elphas Okango, Willem Hanekom, Thumbi Ndung’u, Deenan Pillay, David Bonsall, Emily B. Wong, Frank Tanser, Mark J. Siedner, Ravindra K. Gupta
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Despite expanded antiretroviral therapy (ART) in South Africa, HIV-1 transmission persists. Integrase strand transfer inhibitors (INSTI) and long-acting injectables offer potential for superior viral suppression, but pre-existing drug resist
Externí odkaz:
https://doaj.org/article/89c0e3f21d6f4594a986118e896f7a66
Autor:
Jennifer Manne‐Goehler, June Fabian, Simiso Sokhela, Godspower Akpomiemie, Nicholas Rahim, Samanta Tresha Lalla‐Edward, Alana T. Brennan, Mark J. Siedner, Andrew Hill, Willem Daniel Francois Venter
Publikováno v:
Journal of the International AIDS Society, Vol 27, Iss 7, Pp n/a-n/a (2024)
Abstract Introduction Recent evidence has raised questions about whether newer HIV treatment regimens, including dolutegravir (DTG) and tenofovir alafenamide (TAF), are associated with increases in blood pressure (BP). Methods We assessed changes in
Externí odkaz:
https://doaj.org/article/cd718466e68d4eb5a0c7f607f4ad5280
Autor:
Acadia M. Thielking, Kieran P. Fitzmaurice, Ronel Sewpaul, Stavroula A. Chrysanthopoulou, Lotanna Dike, Douglas E. Levy, Nancy A. Rigotti, Mark J. Siedner, Robin Wood, A. David Paltiel, Kenneth A. Freedberg, Emily P. Hyle, Krishna P. Reddy
Publikováno v:
Journal of the International AIDS Society, Vol 27, Iss 6, Pp n/a-n/a (2024)
Abstract Introduction As access to effective antiretroviral therapy (ART) has improved globally, tobacco‐related illnesses, including cardiovascular disease, cancer and chronic respiratory conditions, account for a growing proportion of deaths amon
Externí odkaz:
https://doaj.org/article/016ed7f709dc4bb8a11b68d4e93be471
Autor:
Muntsa Rocafort, David B. Gootenberg, Jesús M. Luévano, Jeffrey M. Paer, Matthew R. Hayward, Juliet T. Bramante, Musie S. Ghebremichael, Jiawu Xu, Zoe H. Rogers, Alexander R. Munoz, Samson Okello, June-Ho Kim, Ruth Sentongo, Robert Wagubi, Alex Lankowski, Segametsi Maruapula, Guoyan Zhao, Scott A. Handley, Mosepele Mosepele, Mark J. Siedner, Douglas S. Kwon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract HIV-associated changes in intestinal microbiota are believed to be important drivers of disease progression. However, the majority of studies have focused on populations in high-income countries rather than in developing regions where HIV bu
Externí odkaz:
https://doaj.org/article/b80e9de9b259430eb0c139472099a4e5