Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Mark I Rosenblatt"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191962 (2018)
The peripheral sensory nerves that innervate the cornea can be easily damaged by trauma, surgery, infection or diabetes. Several growth factors and axon guidance molecules, such as Semaphorin3A (Sema3A) are upregulated upon cornea injury. Nerves can
Externí odkaz:
https://doaj.org/article/47a86d80ff234f2eae568c2881814181
Autor:
Waleed Abdel-Naby, Brigette Cole, Aihong Liu, Jingbo Liu, Pengxia Wan, Ryan Schreiner, David W Infanger, Nicholas B Paulson, Brian D Lawrence, Mark I Rosenblatt
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188154 (2017)
There is a significant clinical need to improve current therapeutic approaches to treat ocular surface injuries and disease, which affect hundreds of millions of people annually worldwide. The work presented here demonstrates that the presence of Sil
Externí odkaz:
https://doaj.org/article/31531afdcdf447758b9bf59de3bd3f93
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50190 (2012)
The following study provides new insight into how surface topography dictates directed collective epithelial cell sheet growth through the guidance of individual cell movement. Collective cell behavior of migrating human corneal limbal-epithelial cel
Externí odkaz:
https://doaj.org/article/2aa288ad369440adbee4fc234b0d4b83
Autor:
Ghasem Yazdanpanah, Elmira Jalilian, Xiang Shen, Khandaker N. Anwar, Yizhou Jiang, Sayena Jabbehdari, Mark I. Rosenblatt, Yayue Pan, Ali R. Djalilian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract To compare the effects of two decellularization protocols on the characteristics of fabricated COrnea Matrix (COMatrix) hydrogels. Porcine corneas were decellularized with Detergent (De) or Freeze–Thaw (FT)-based protocols. DNA remnant, ti
Externí odkaz:
https://doaj.org/article/d11e31b5fde443ab9f8546b73c527fd9
Autor:
Elmira Jalilian, Hamed Massoumi, Bianca Bigit, Sohil Amin, Eitan A. Katz, Victor H. Guaiquil, Khandaker N. Anwar, Peiman Hematti, Mark I. Rosenblatt, Ali R. Djalilian
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Highlights Extracellular vesicles (EV) derived from 2D and 3D bone marrow mesenchymal stromal cells (BM-MSCs) demonstrate different characterization phenotype. Heterogeneity and concentration of BM-MSCs-derived extracellular vesicles are highly impac
Externí odkaz:
https://doaj.org/article/a3f0166119db4492a0b92fde15130984
Autor:
Yuncin Luo, Kai B. Kang, Rachel Sartaj, Michael G. Sun, Qiang Zhou, Victor H. Guaiquil, Mark I. Rosenblatt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Corneal wound healing depends on extracellular matrix (ECM) and topographical cues that modulate migration and proliferation of regenerating cells. In our study, silk films with either flat or nanotopography patterned parallel ridge widths o
Externí odkaz:
https://doaj.org/article/8028378e37924883a8098fa07dfd293a
Autor:
Mehul Patnam, Sunil R. Dommaraju, Faisal Masood, Paula Herbst, Jin-Hong Chang, Wen-Yang Hu, Mark I. Rosenblatt, Dimitri T. Azar
Publikováno v:
Cells, Vol 12, Iss 2, p 319 (2023)
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection. Following injury, corneal (lymph)angiogenic privilege is impaired,
Externí odkaz:
https://doaj.org/article/f1884d6bb86f4c1988151ee43173a934
Autor:
Faisal Masood, Jin-Hong Chang, Anosh Akbar, Amy Song, Wen-Yang Hu, Dimitri T. Azar, Mark I. Rosenblatt
Publikováno v:
Cells, Vol 11, Iss 20, p 3247 (2022)
Limbal stem cells constitute an important cell population required for regeneration of the corneal epithelium. If insults to limbal stem cells or their niche are sufficiently severe, a disease known as limbal stem cell deficiency occurs. In the absen
Externí odkaz:
https://doaj.org/article/49e351a61db445f7b7e5f28ff4b442a8
Autor:
Sohil Amin, Elmira Jalilian, Eitan Katz, Charlie Frank, Ghasem Yazdanpanah, Victor H. Guaiquil, Mark I. Rosenblatt, Ali R. Djalilian
Publikováno v:
Vision, Vol 5, Iss 4, p 43 (2021)
The protective function and transparency provided by the corneal epithelium are dependent on and maintained by the regenerative capacity of limbal epithelial stem cells (LESCs). These LESCs are supported by the limbal niche, a specialized microenviro
Externí odkaz:
https://doaj.org/article/1ac2166d041e45a4bca989dcd111deb8
Autor:
Abdelrahman M Elhusseiny, Mohammad Soleimani, Taher K Eleiwa, Reem H ElSheikh, Charles R Frank, Morteza Naderan, Ghasem Yazdanpanah, Mark I Rosenblatt, Ali R Djalilian
Publikováno v:
Stem Cells Translational Medicine. 11:259-268
The corneal epithelium serves to protect the underlying cornea from the external environment and is essential for corneal transparency and optimal visual function. Regeneration of this epithelium is dependent on a population of stem cells residing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6610b2ca2d08dc371219641456e5d68e
https://doi.org/10.1093/stcltm/szab028
https://doi.org/10.1093/stcltm/szab028