Výsledky vyhledávání

Hereditary Susceptibility to Breast Cancer: Significance of Age of Onset in Family History and Contribution of BRCA1 and BRCA2

Autor: Kathryn Gumpper, Thomas S. Frank, Mark Hulick, Amie M. Deffenbaugh

Publikováno v: Disease Markers, Vol 15, Iss 1-3, Pp 89-92 (1999)
Disease Markers

OBJECTIVE: To correlate mutations in BRCA1 and BRCA2 with family history of breast cancer in a first-degree relative for women diagnosed with breast cancer before age 45 who do not have a personal or family history of ovarian cancer.METHODS: Family h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9649c04c5cfb9a138c55a95763385b2f
https://doaj.org/article/1efd89b921494bf18808bfcdc78c1b84

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Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals

Autor: Thomas S. Frank, Amie M. Deffenbaugh, Julia E. Reid, Mark Hulick, Brian E. Ward, Beth Lingenfelter, Kathi L. Gumpper, Thomas Scholl, Sean V. Tavtigian, Dmitry R. Pruss, Gregory C. Critchfield

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(6)

PURPOSE: To assess the characteristics that correlate best with the presence of mutations in BRCA1 and BRCA2 in individuals tested in a clinical setting. PATIENTS AND METHODS: The results of 10,000 consecutive gene sequence analyses performed to iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3141a6f517e854150879af44ca59f1eb
https://pubmed.ncbi.nlm.nih.gov/17577048

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Hereditary susceptibility to breast cancer: Significance of age of onset in family history and contribution of and

Autor: Thomas S. Frank, Kathryn Gumpper, Mark Hulick, Amie M. Deffenbaugh

Publikováno v: Obstetrics & Gynecology. 93:S32

revised): OBJECTIVE: To correlate mutations in BRCA1 and BRCA2 with family history of breast cancer in a first-degree relative for women diagnosed with breast cancer before age 45 who do not have a personal or family history of ovarian cancer. METHOD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95d2403fabaaff82a3bf205253df86d2
https://doi.org/10.1016/s0029-7844(99)90066-2

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BRCA1 sequence analysis in women at high risk for susceptibility mutations: Risk factor analysis and implications for genetic testing

Autor: Isidore Tepler, Ron Lundstrom, Melody McClure, Frank Fujimura, Charlene Schulz, Kathryn Gumpper, Nils Adey, Heather Hampel, Sean V. Tavtigian, Mary B. Daly, Paul L. Weinstein, Dmitry Pruss, Beth N. Peshkin, Richard Michaelson, Alun Thomas, John Holmen, Donna M Shattuck-Eidens, Rodney J. Scott, A. Schluger, Starlene Loader, Seppo Pyrhonen, Karen T. Brown, Marco A. Pierotti, Brian E. Ward, Lisa A. Cannon-Albright, Robert M. Greenstein, Susan Manley, Kenneth Offit, Michael C. Luce, David H. F. Teng, Elena Giulotto, Michael P. Osborne, Alberto Ravaioli, Celeste McBride, Wainer Zoli, Heli Nevanlinna, Linda Steele, Teresa Gilewski, Larry Norton, Mark Hulick, Barbara L. Weber, Judy Garber, Mark Kelly, Jennifer L. Scalia, Renate Burgemeister, Mark H. Skolnick, Thomas S. Frank, Jamila Gupte, Claudine Isaacs, Arnold R. Oliphant, Todd Rubano, Maria A. Caligo, Marc E. Lippman, Robert Pilarski, Paolo Radice, Mark Staebell, Beth Lingenfelter, Michael H. Dosik, Peter T. Rowley

Publikováno v: Scopus-Elsevier

Octext. —A mutation in theBRCA1gene may confer substantial risk for breast and/or ovarian cancer. However, knowledge regarding all possible mutations and the relationship between risk factors and mutations is incomplete. Objectives. —To identifyB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d498cc593f5898b028f187413dd5a7
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030852505&partnerID=MN8TOARS

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