Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Mark Hargreaves"'
Autor:
Vidhi Gaur, Timothy Connor, Andrew Sanigorski, Sheree D. Martin, Clinton R. Bruce, Darren C. Henstridge, Simon T. Bond, Kevin A. McEwen, Lyndal Kerr-Bayles, Trent D. Ashton, Cassandra Fleming, Min Wu, Lisa S. Pike Winer, Denise Chen, Gregg M. Hudson, John W.R. Schwabe, Keith Baar, Mark A. Febbraio, Paul Gregorevic, Frederick M. Pfeffer, Ken R. Walder, Mark Hargreaves, Sean L. McGee
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2802-2810 (2016)
Drugs that recapitulate aspects of the exercise adaptive response have the potential to provide better treatment for diseases associated with physical inactivity. We previously observed reduced skeletal muscle class IIa HDAC (histone deacetylase) tra
Externí odkaz:
https://doaj.org/article/edcebf20f6354f6bb76e658132df2dd0
Autor:
Andrew Garnham, Barnaby P. Frankish, Robyn M. Murphy, Mark Hargreaves, David Stapleton, Marcelo Flores-Opazo
Publikováno v:
Physiological Reports
Previous studies have demonstrated that exercise increases whole body and skeletal muscle insulin sensitivity that is linked with increased GLUT4 at the plasma membrane following insulin stimulation and associated with muscle glycogen depletion. To a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e964c18967eb7d5f3171e38ddadcbc
Autor:
Robyn M. Murphy, Sean L. McGee, Mark Hargreaves, Marcelo Flores-Opazo, Eva Boland, Andrew Garnham
Publikováno v:
Physiological Reports
To examine the effect of acute and chronic exercise on adipose tissue GLUT4 expression, a total of 20 healthy, male subjects performed one of two studies. Ten subjects performed cycle ergometer exercise for 60 min at 73 ± 2% VO 2 peak and abdominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951f7a3b16faca53448475e12f162bbf
Autor:
Lawrence L. Spriet, Mark Hargreaves
Publikováno v:
Nature Metabolism. 2:817-828
The continual supply of ATP to the fundamental cellular processes that underpin skeletal muscle contraction during exercise is essential for sports performance in events lasting seconds to several hours. Because the muscle stores of ATP are small, me
Autor:
Mark Hargreaves, Sean L. McGee
Publikováno v:
Nature Reviews Endocrinology. 16:495-505
Exercise is fundamental for good health, whereas physical inactivity underpins many chronic diseases of modern society. It is well appreciated that regular exercise improves metabolism and the metabolic phenotype in a number of tissues. The phenotypi
Publikováno v:
Exercise and Sport Sciences Reviews. 48:110-118
The glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the sarcolemma and t-tubule and, over the longer term, total GLUT4 protein
Autor:
Mark Hargreaves
Publikováno v:
Physiology in Health and Disease ISBN: 9783030943042
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19dcef03866fa09bce60c3848fbe9429
https://doi.org/10.1007/978-3-030-94305-9_2
https://doi.org/10.1007/978-3-030-94305-9_2
Autor:
Mark Hargreaves
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 131(2)
Since ancient times, the health benefits of regular physical activity/exercise have been recognized and the classic studies of Morris and Paffenbarger provided the epidemiological evidence in support of such an association. Cardiorespiratory fitness,
Autor:
Sean L. McGee, Mark Hargreaves
Publikováno v:
Trends in Endocrinology & Metabolism. 30:636-645
Epigenetics can be defined as 'the structural adaptation of chromosomal regions so as to register, signal, or perpetuate altered activity states.' Increased transcription of key regulatory, metabolic, and myogenic genes is an early response to exerci
Publikováno v:
Experimental Physiology. 104:630-634
New findings What is the central question of this study? Do circulating factors mediate exercise-induced effects on adipose tissue GLUT4 expression? What is the main finding and its importance? Serum (10%) obtained from human volunteers immediately a