Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Mark H. Soonpaa"'
Autor:
Sean P. Reuter, Mark H. Soonpaa, Dorothy Field, Ed Simpson, Michael Rubart-von der Lohe, Han Kyu Lee, Arthi Sridhar, Stephanie M. Ware, Nick Green, Xiaochun Li, Susan Ofner, Douglas A. Marchuk, Kai C. Wollert, Loren J. Field
Publikováno v:
Circulation.
Background: Identifying genetic variants that affect the level of cell cycle reentry and establishing the degree of cell cycle progression in those variants could help guide development of therapeutic interventions aimed at effecting cardiac regenera
Autor:
Tao Yang, Michael Rubart, Mark H Soonpaa, Michael Didié, Peter Christalla, Wolfram-Hubertus Zimmermann, Loren J Field
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131511 (2015)
Parthenogenetic stem cells (PSCs) are a promising candidate donor for cell therapy applications. Similar to embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), PSCs exhibit self-renewing capacity and clonogenic proliferation in vi
Externí odkaz:
https://doaj.org/article/d171af37d36144aea209eadf6476deb4
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115871 (2014)
Neuregulin 1 signaling plays an important role in cardiac trabecular development, and in sustaining functional integrity in adult hearts. Treatment with neuregulin 1 enhances adult cardiomyocyte differentiation, survival and/or function in vitro and
Externí odkaz:
https://doaj.org/article/c69ed058fd7c4bc3b1f31fdedd4e58f4
Autor:
Lincoln T Shenje, Loren J Field, Catrin A Pritchard, Christopher J Guerin, Michael Rubart, Mark H Soonpaa, Keng-Leong Ang, Manuel Galiñanes
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1929 (2008)
Cultured cardiac explants produce a heterogeneous population of cells including a distinctive population of refractile cells described here as small round cardiac explant derived cells (EDCs). The aim of this study was to explore the source, morpholo
Externí odkaz:
https://doaj.org/article/993c4e93a7f24493841753436f9a0374
Autor:
Simon J. Conway, Mark H. Soonpaa, Xiao-Long Lu, Shien-Fong Lin, Wen Tao, Sean Reuter, Michael Rubart
Publikováno v:
Cardiovascular Research. 114:389-400
Aims Recent studies have demonstrated electrotonic coupling between scar tissue and the surrounding myocardium in cryoinjured hearts. However, the electrical dynamics occurring at the myocyte-nonmyocyte interface in the fibrotic heart remain undefine
Autor:
Mark H. Soonpaa, Loren J. Field
Publikováno v:
ESC CardioMed
After the commitment and differentiation of cardiomyogenic progenitor cells, increases in myocardial mass during embryogenesis result largely from the proliferation of pre-existing, contracting cardiomyocytes. During perinatal life, cardiomyocyte pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d21d38336722ca3c08ec1300f0b29875
https://doi.org/10.1093/med/9780198784906.003.0010
https://doi.org/10.1093/med/9780198784906.003.0010
Publikováno v:
Journal of Neuroscience Methods. 221:48-61
Sympathetic nerve wiring in the mammalian heart has remained largely unexplored. Resolving the wiring diagram of the cardiac sympathetic network would help establish the structural underpinnings of neurocardiac coupling.We used two-photon excitation
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833(4):799-803
Interventions to effect therapeutic cardiomyocyte renewal have received considerable interest of late. Such interventions, if successful, could give rise to myocardial regeneration in diseased hearts. Regenerative interventions fall into two broad ca
Autor:
Hans R. Schöler, Sigrid Fuchs, Ali El-Armouche, Alexander Becker, Thomas Rau, Thomas Eschenhagen, Michael Rubart, Dong Wook Han, Martin Zenke, Bernhard Unsöld, Claudia Lange, Udo Schumacher, Peter Christalla, Alec D. Witty, Steven J. Kattman, Michael Didié, Stephan Döker, Heimo Ehmke, Gordon Keller, Vijayakumar Muppala, Mark H. Soonpaa, Loren J. Field, Tao Yang, Cornelia Rudolph, Wolfram-Hubertus Zimmermann, Brigitte Schlegelberger, Wen Tao, Doris Steinemann, Qiong Lin, John A. Scherschel, Alexander P. Schwoerer
Publikováno v:
The Journal of Clinical Investigation, 123(3), 1285-1298. AMER SOC CLINICAL INVESTIGATION INC
Uniparental parthenotes are considered an unwanted byproduct of in vitro fertilization. In utero parthenote development is severely compromised by defective organogenesis and in particular by defective cardiogenesis. Although developmentally compromi
Publikováno v:
Biophysical Journal. 110(3)
In vitro and in silico studies have claimed that electrically non-excitable cells, such as myofibroblasts populating the chronically infarcted heart, couple by gap junctions to adjacent cardiomyocytes, evoking arrhythmogenic electrotonic interactions