Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mark H. G. Verheijen"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) have proven themselves as one of the key in vivo techniques of modern neuroscience, allowing for unprecedented access to cellular manipulations in living animals. With respect to as
Externí odkaz:
https://doaj.org/article/695ed000eb5640b3989e6081aebfff87
Autor:
Mandy S. J. Kater, Aina Badia-Soteras, Jan R. T. van Weering, August B. Smit, Mark H. G. Verheijen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionAstrocyte-synapse bi-directional communication is required for neuronal development and synaptic plasticity. Astrocytes structurally interact with synapses using their distal processes also known as leaflets or perisynaptic astrocytic pro
Externí odkaz:
https://doaj.org/article/3d62eb5ad2004914a8d204ba68f7a436
Autor:
Aina Badia-Soteras, Janneke de Vries, Werner Dykstra, Laus M. Broersen, Jan Martin Verkuyl, August B. Smit, Mark H. G. Verheijen
Publikováno v:
Cells, Vol 11, Iss 9, p 1428 (2022)
Astrocytes are specialized glial cells that tile the central nervous system (CNS) and perform numerous essential functions. Astrocytes react to various forms of CNS insults by altering their morphology and molecular profile, through a process known a
Externí odkaz:
https://doaj.org/article/fa63eec134894d7f8668ece4a1f682d4
Publikováno v:
Cells, Vol 9, Iss 9, p 2119 (2020)
Myelination greatly increases the speed of action potential propagation of neurons, thereby enhancing the efficacy of inter-neuronal communication and hence, potentially, optimizing the brain’s signal processing capability. The impact of genetic va
Externí odkaz:
https://doaj.org/article/fc295e05949f45b7af8395c4829284d2
Autor:
Anne-Lieke F. van Deijk, Laus M. Broersen, J. Martin Verkuyl, August B. Smit, Mark H. G. Verheijen
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Neuronal and synaptic membranes are composed of a phospholipid bilayer. Supplementation with dietary precursors for phospholipid synthesis –docosahexaenoic acid (DHA), uridine and choline– has been shown to increase neurite outgrowth and synaptog
Externí odkaz:
https://doaj.org/article/3f96caf2f67849ada4555cbe99945786
Autor:
Mandy S. J. Kater, Katharina F. Baumgart, Aina Badia‐Soteras, Tim S. Heistek, Karen E. Carney, A. Jacob Timmerman, Jan R. T. van Weering, August B. Smit, Marjo S. van der Knaap, Huibert D. Mansvelder, Mark H. G. Verheijen, Rogier Min
Publikováno v:
Kater, M S J, Baumgart, K F, Badia-Soteras, A, Heistek, T S, Carney, K E, Timmerman, A J, van Weering, J R T, Smit, A B, van der Knaap, M S, Mansvelder, H D, Verheijen, M H G & Min, R 2023, ' A novel role for MLC1 in regulating astrocyte–synapse interactions ', GLIA, vol. 71, no. 7, pp. 1770-1785 . https://doi.org/10.1002/glia.24368
Glia, 71(7), 1770-1785. John Wiley and Sons Inc.
GLIA, 71(7), 1770-1785. John Wiley and Sons Inc.
Kater, M S J, Baumgart, K F, Badia-Soteras, A, Heistek, T S, Carney, K E, Timmerman, A J, van Weering, J R T, Smit, A B, van der Knaap, M S, Mansvelder, H D, Verheijen, M H G & Min, R 2023, ' A novel role for MLC1 in regulating astrocyte–synapse interactions ', Glia, vol. 71, no. 7, pp. 1770-1785 . https://doi.org/10.1002/glia.24368
Glia, 71(7), 1770-1785. John Wiley and Sons Inc.
GLIA, 71(7), 1770-1785. John Wiley and Sons Inc.
Kater, M S J, Baumgart, K F, Badia-Soteras, A, Heistek, T S, Carney, K E, Timmerman, A J, van Weering, J R T, Smit, A B, van der Knaap, M S, Mansvelder, H D, Verheijen, M H G & Min, R 2023, ' A novel role for MLC1 in regulating astrocyte–synapse interactions ', Glia, vol. 71, no. 7, pp. 1770-1785 . https://doi.org/10.1002/glia.24368
Loss of function of the astrocyte membrane protein MLC1 is the primary genetic cause of the rare white matter disease Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC), which is characterized by disrupted brain ion and water homeostasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33cbe10cd35672d6014c75fbbae2d06
https://research.vumc.nl/en/publications/4a3453d2-881d-4b24-bf30-c4e9ae534160
https://research.vumc.nl/en/publications/4a3453d2-881d-4b24-bf30-c4e9ae534160
Autor:
Nutabi Camargo, Andrea Goudriaan, Anne-Lieke F van Deijk, Willem M Otte, Jos F Brouwers, Hans Lodder, David H Gutmann, Klaus-Armin Nave, Rick M Dijkhuizen, Huibert D Mansvelder, Roman Chrast, August B Smit, Mark H G Verheijen
Publikováno v:
PLoS Biology, Vol 15, Iss 5, p e1002605 (2017)
In the vertebrate nervous system, myelination of axons for rapid impulse propagation requires the synthesis of large amounts of lipids and proteins by oligodendrocytes and Schwann cells. Myelin membranes are thought to be cell-autonomously assembled
Externí odkaz:
https://doaj.org/article/fa45eb58e4e8409aaacc928116f4a1f4
Autor:
Aina Badia-Soteras, Tim S Heistek, Mandy S J Kater, Adrian Negrean, Huibert D Mansvelder, Baljit S Khakh, Rogier Min, August B Smit, Mark H G Verheijen
SummaryAstrocyte distal processes, known as leaflets or perisynaptic astrocyte processes (PAPs), fine-tune synaptic activity by clearing neurotransmitters and limiting extrasynaptic glutamate diffusion. While learning and memory depends on orchestrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e00dbada5a4b8764d92782179565d8
https://doi.org/10.1101/2022.01.30.478393
https://doi.org/10.1101/2022.01.30.478393
Autor:
Vivi M. Heine, Anne-Lieke F van Deijk, Mark H. G. Verheijen, Maralinde R. Abbink, Aniko Korosi
Publikováno v:
Abbink, M R, Deijk, AL F, Heine, V M, Verheijen, M H & Korosi, A 2019, ' The involvement of astrocytes in early-life adversity induced programming of the brain ', Glia, vol. 67, no. 9, pp. 1637-1653 . https://doi.org/10.1002/glia.23625
Glia
Glia, 67(9), 1637-1653. John Wiley and Sons Inc.
Glia
Glia, 67(9), 1637-1653. John Wiley and Sons Inc.
Early‐life adversity (ELA) in the form of stress, inflammation, or malnutrition, can increase the risk of developing psychopathology or cognitive problems in adulthood. The neurobiological substrates underlying this process remain unclear. While ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb201cc62bb58da68f388c5d4c736aa
https://doi.org/10.1002/glia.23625
https://doi.org/10.1002/glia.23625
Autor:
Sander Bobeldijk, Mark H. G. Verheijen, Adri A. M. Thomas, Douwe Molenaar, Eduard A. Struijs, Marianna Bugiani, Timo J. ter Braak, Nienke L. Postma, Truus Em Abbink, Lisanne E. Wisse, Daniel Voltolini-González, Emiel Polder, Sophie van der Sluis, Michiel J. Thiecke, Ermelinda Jaku, Marjo S. van der Knaap, Hein Fritsen, Nina Straat
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1407-1422 (2019)
Abbink, T E M, Wisse, L E, Jaku, E, Thiecke, M J, Voltolini-González, D, Fritsen, H, Bobeldijk, S, ter Braak, T J, Polder, E, Postma, N L, Bugiani, M, Struijs, E A, Verheijen, M, Straat, N, van der Sluis, S, Thomas, A A M, Molenaar, D & van der Knaap, M S 2019, ' Vanishing white matter: deregulated integrated stress response as therapy target ', Annals of Clinical and Translational Neurology, vol. 6, no. 8, pp. 1407-1422 . https://doi.org/10.1002/acn3.50826
Abbink, T E M, Wisse, L E, Jaku, E, Thiecke, M J, Voltolini-González, D, Fritsen, H, Bobeldijk, S, ter Braak, T J, Polder, E, Postma, N L, Bugiani, M, Struijs, E A, Verheijen, M, Straat, N, van der Sluis, S, Thomas, A A M, Molenaar, D & van der Knaap, M S 2019, ' Vanishing white matter : deregulated integrated stress response as therapy target ', Annals of Clinical and Translational Neurology, vol. 6, no. 8, pp. 1407-1422 . https://doi.org/10.1002/acn3.50826
Annals of Clinical and Translational Neurology, 6(8), 1407-1422. John Wiley and Sons Ltd
Annals of Clinical and Translational Neurology
Abbink, T E M, Wisse, L E, Jaku, E, Thiecke, M J, Voltolini-González, D, Fritsen, H, Bobeldijk, S, ter Braak, T J, Polder, E, Postma, N L, Bugiani, M, Struijs, E A, Verheijen, M, Straat, N, van der Sluis, S, Thomas, A A M, Molenaar, D & van der Knaap, M S 2019, ' Vanishing white matter: deregulated integrated stress response as therapy target ', Annals of Clinical and Translational Neurology, vol. 6, no. 8, pp. 1407-1422 . https://doi.org/10.1002/acn3.50826
Abbink, T E M, Wisse, L E, Jaku, E, Thiecke, M J, Voltolini-González, D, Fritsen, H, Bobeldijk, S, ter Braak, T J, Polder, E, Postma, N L, Bugiani, M, Struijs, E A, Verheijen, M, Straat, N, van der Sluis, S, Thomas, A A M, Molenaar, D & van der Knaap, M S 2019, ' Vanishing white matter : deregulated integrated stress response as therapy target ', Annals of Clinical and Translational Neurology, vol. 6, no. 8, pp. 1407-1422 . https://doi.org/10.1002/acn3.50826
Annals of Clinical and Translational Neurology, 6(8), 1407-1422. John Wiley and Sons Ltd
Annals of Clinical and Translational Neurology
Objective: Vanishing white matter (VWM) is a fatal, stress-sensitive leukodystrophy that mainly affects children and is currently without treatment. VWM is caused by recessive mutations in eukaryotic initiation factor 2B (eIF2B) that is crucial for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc38ffb7fe3629e60ea3de02637fcbd1
https://doi.org/10.1002/acn3.50826
https://doi.org/10.1002/acn3.50826