Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mark H Pitcher"'
Autor:
Arkady Khoutorsky, Robert P Bonin, Robert E Sorge, Christos G Gkogkas, Sophie Anne Pawlowski, Seyed Mehdi Jafarnejad, Mark H Pitcher, Tommy Alain, Jimena Perez-Sanchez, Eric W Salter, Loren Martin, Alfredo Ribeiro-da-Silva, Yves De Koninck, Fernando Cervero, Jeffrey S Mogil, Nahum Sonenberg
Publikováno v:
eLife, Vol 4 (2015)
Activation of the mechanistic/mammalian target of rapamycin (mTOR) kinase in models of acute and chronic pain is strongly implicated in mediating enhanced translation and hyperalgesia. However, the molecular mechanisms by which mTOR regulates nocicep
Externí odkaz:
https://doaj.org/article/1646d0777a1b4f18ab3e65cd60d5602c
Autor:
Laura K. Case, Jaquette Liljencrantz, Nicholas Madian, Aaron Necaise, Justin Tubbs, Micaela McCall, Megan L. Bradson, Marcin Szczot, Mark H. Pitcher, Nima Ghitani, Eleni Frangos, Jonathan Cole, Diana Bharucha-Goebel, Dimah Saade, Tracy Ogata, Sandra Donkervoort, A. Reghan Foley, Carsten G. Bönnemann, Håkan Olausson, M. Catherine Bushnell, Alexander T. Chesler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The mechanisms underlying deep pressure sensing are not fully understood. Here the authors demonstrate that while two individuals lacking Aβ fibers demonstrate impaired deep pressure sensing, seven individuals with PIEZO2 loss of function mutations
Externí odkaz:
https://doaj.org/article/b005162b0b26483ea9700b4ecfd44b19
Publikováno v:
Stress and Health.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cecdf8585488a093ae6fa8e7f23d40b
https://doi.org/10.1002/smi.3276
https://doi.org/10.1002/smi.3276
Autor:
Anthony F. Domenichiello, Breanne C. Wilhite, Pranavi Nara, Mark H. Pitcher, Gregory S. Keyes, Andrew J. Mannes, M. Catherine Bushnell, Christopher E. Ramsden
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 187:102512
Clinical studies have demonstrated that decreasing linoleic acid (LA) while increasing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in diets evokes an analgesic effect in headache sufferers. We utilized a rat chronic monoarthritis model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385cbeb557318b6cec2c13dd391eac8b
https://doi.org/10.1016/j.plefa.2022.102512
https://doi.org/10.1016/j.plefa.2022.102512
Publikováno v:
Behavioural brain research
Urine from pro-œstrus female rodents evokes increased levels of sexually-motivated behaviors in males, including sniffing and scent marking of the urine spot as well as activation of brain reward regions. Stressors such as social defeat can adversel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7796976bc0226d26a170189e5320c8
https://doi.org/10.1016/j.bbr.2018.09.001
https://doi.org/10.1016/j.bbr.2018.09.001
Autor:
Anthony F. Domenichiello, Jennifer R. Jensen, Christopher E. Ramsden, Zhi-Xin Yuan, Mark H. Pitcher
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 135:128-136
Chronic pain is both a global public health concern and a serious source of personal suffering for which current treatments have limited efficacy. Recently, oxylipins derived from linoleic acid (LA), the most abundantly consumed polyunsaturated fatty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597e4b2177ab3f0518daf6e33301e174
https://doi.org/10.1016/j.plefa.2018.07.015
https://doi.org/10.1016/j.plefa.2018.07.015
Autor:
Mark H. Pitcher
Publikováno v:
Current Osteoporosis Reports
Purpose of Review Physical activity is increasingly recommended for chronic pain. In this review, we briefly survey recent, high-quality meta-analyses on the effects of exercise in human chronic pain populations, followed by a critical discussion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d9eabdaef5f1b7e0f839ddd0e1e1d6
http://europepmc.org/articles/PMC6061206
http://europepmc.org/articles/PMC6061206
Autor:
Justin D. Tubbs, Laura K. Case, Eleni Frangos, Diana Bharucha-Goebel, Nima Ghitani, Håkan Olausson, Dimah Saade, Mark H. Pitcher, Jonathan Cole, Nicholas Madian, Aaron Necaise, Micaela V. McCall, Jaquette Liljencrantz, Marcin Szczot, Alexander T. Chesler, Sandra Donkervoort, A. Reghan Foley, Megan Bradson, Tracy Ogata, Carsten G. Bönnemann, M. Catherine Bushnell
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The sensation of pressure allows us to feel sustained compression and body strain. While our understanding of cutaneous touch has grown significantly in recent years, how deep tissue sensations are detected remains less clear. Here, we use quantitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6304e2c500bdc44e67acd60a29517869
https://pubmed.ncbi.nlm.nih.gov/33510158
https://pubmed.ncbi.nlm.nih.gov/33510158
Publikováno v:
Pain
Restraint training caused long-lasting reductions in pain behavior, in response to the formalin test, and increases in amygdala cell activation.
With the increased interest in longitudinal brain imaging of awake rodents, it is important to under
With the increased interest in longitudinal brain imaging of awake rodents, it is important to under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04c8bfd703c8cc1425cba7a1a610602
https://doi.org/10.1097/j.pain.0000000000000579
https://doi.org/10.1097/j.pain.0000000000000579
Publikováno v:
The journal of pain. 20(2)
The multidimensional nature of chronic pain is not reflected by definitions based solely on pain duration, resulting in high prevalence estimates limiting effective policy development. The newly proposed concept of high-impact chronic pain (HICP) inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe8abbdb2eaa625cb3dd5abade34560
https://pubmed.ncbi.nlm.nih.gov/30096445
https://pubmed.ncbi.nlm.nih.gov/30096445