Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark G. Hegarty"'
Autor:
Holly J. Butler, Paul M. Brennan, James M. Cameron, Duncan Finlayson, Mark G. Hegarty, Michael D. Jenkinson, David S. Palmer, Benjamin R. Smith, Matthew J. Baker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Diagnosing brain cancer is frequently difficult and requires specialist equipment. Here, the authors develop their previous attenuated total reflectance-Fourier transform infrared spectroscopy method and incoporate the use of disposable silicon wafer
Externí odkaz:
https://doaj.org/article/5b3dd95709634629b026079f78f90af9
Autor:
James M. Cameron, Alexandra Sala, Georgios Antoniou, Paul M. Brennan, Holly J. Butler, Justin J.A. Conn, Siobhan Connal, Tom Curran, Mark G. Hegarty, Rose McHardy, Daniel Orringer, David S. Palmer, Benjamin R. Smith, Matthew J. Baker
A rapid, low-cost, sensitive, multi-cancer early detection (MCED) test would be transformational in the diagnostics field. Earlier cancer detection can increase survival rates and quality of life of patients. An effective test must accurately identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25f278d963a3a14309b96d274da57bc8
https://doi.org/10.21203/rs.3.rs-1696059/v1
https://doi.org/10.21203/rs.3.rs-1696059/v1
Autor:
James M Cameron, Paul M Brennan, Georgios Antoniou, Holly J Butler, Loren Christie, Justin J A Conn, Tom Curran, Ewan Gray, Mark G Hegarty, Michael D Jenkinson, Daniel Orringer, David S Palmer, Alexandra Sala, Benjamin R Smith, Matthew J Baker
Publikováno v:
Neuro-oncology advances
Cameron, J M, Brennan, P M, Antoniou, G, Butler, H J, Christie, L, Conn, J J A, Curran, T, Gray, E, Hegarty, M G, Jenkinson, M D, Orringer, D, Palmer, D S, Sala, A, Smith, B R & Baker, M J 2022, ' Clinical validation of a spectroscopic liquid biopsy for earlier detection of brain cancer ', Neuro-Oncology Advances, vol. 4, no. 1 . https://doi.org/10.1093/noajnl/vdac024
Cameron, J M, Brennan, P M, Antoniou, G, Butler, H J, Christie, L, Conn, J J A, Curran, T, Gray, E, Hegarty, M G, Jenkinson, M D, Orringer, D, Palmer, D S, Sala, A, Smith, B R & Baker, M J 2022, ' Clinical validation of a spectroscopic liquid biopsy for earlier detection of brain cancer ', Neuro-Oncology Advances, vol. 4, no. 1 . https://doi.org/10.1093/noajnl/vdac024
Background Diagnostic delays impact the quality of life and survival of patients with brain tumors. Earlier and expeditious diagnoses in these patients are crucial to reduce the morbidities and mortalities associated with brain tumors. A simple, rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21721b597d193ca51d9764ebc406c27e
Autor:
James M. Cameron, Paul M. Brennan, Georgios Antoniou, Holly J. Butler, Loren Christie, Justin J.A. Conn, Tom Curran, Ewan Gray, Mark G. Hegarty, Michael Jenkinson, Daniel Orringer, David S. Palmer, Alexandra Sala, Benjamin R. Smith, Matthew J. Baker
Publikováno v:
Cancer Research. 82:5922-5922
Diagnostic delays impact the quality of life and survival of patients with brain tumors. Earlier and expeditious diagnoses in these patients are crucial to reducing the morbidities and mortalities associated with brain tumors. A simple, rapid blood t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ba375316f02a35ac03bd9ccdff78183
https://doi.org/10.1158/1538-7445.am2022-5922
https://doi.org/10.1158/1538-7445.am2022-5922
Autor:
Catriona Keerie, David S. Palmer, Benjamin Smith, John Norrie, Rachel O'Brien, Matthew J. Baker, Michael D. Jenkinson, Loren Christie, Mark G. Hegarty, Paul Brennan, Holly J. Butler
Publikováno v:
Brennan, P M, Butler, H J, Christie, L, Hegarty, M G, Jenkinson, M D, Keerie, C, Norrie, J, O’brien, R, Palmer, D S, Smith, B R & Baker, M J 2021, ' Early diagnosis of brain tumours using a novel spectroscopic liquid biopsy ', Brain Communications . https://doi.org/10.1093/braincomms/fcab056
Brain Communications
Brain Communications
Early diagnosis of brain tumours is challenging and a major unmet need. Patients with brain tumours most often present with non-specific symptoms more commonly associated with less serious diagnoses, making it difficult to determine which patients to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d810a822fed540997fe69181d1f56d
https://hdl.handle.net/20.500.11820/34a74ea3-830d-4886-a768-c803cc3de88f
https://hdl.handle.net/20.500.11820/34a74ea3-830d-4886-a768-c803cc3de88f
Autor:
David S. Palmer, James Cameron, Paul Brennan, Mark G. Hegarty, Matthew J. Baker, Holly J. Butler, Michael D. Jenkinson, Ewan Gray
Publikováno v:
Gray, E, Cameron, J M, Butler, H J, Jenkinson, M D, Hegarty, M G, Palmer, D S, Brennan, P M & Baker, M J 2021, ' Early economic evaluation to guide the development of a spectroscopic liquid biopsy for the detection of brain cancer ', International journal of technology assessment in health care, vol. 37 . https://doi.org/10.1017/S0266462321000143
International Journal of Technology Assessment in Health Care
International Journal of Technology Assessment in Health Care
Objectives An early economic evaluation to inform the translation into clinical practice of a spectroscopic liquid biopsy for the detection of brain cancer. Two specific aims are (1) to update an existing economic model with results from a prospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2250484758236cf417c911bf22dad585
https://strathprints.strath.ac.uk/75776/7/Gray_etal_IJTAHC_2021_Early_economic_evaluation_to_guide_the_development_of_a_spectroscopic_liquid_biopsy.pdf
https://strathprints.strath.ac.uk/75776/7/Gray_etal_IJTAHC_2021_Early_economic_evaluation_to_guide_the_development_of_a_spectroscopic_liquid_biopsy.pdf
Autor:
James Cameron, Holly J. Butler, Michael D. Jenkinson, Mark G. Hegarty, Christopher Rinaldi, Katherine M. Ashton, David S. Palmer, Matthew J. Baker, Khaja Syed, Paul Brennan, Timothy Dawson
Publikováno v:
Cancers, Vol 12, Iss 1710, p 1710 (2020)
Cancers
Cameron, J M, Rinaldi, C, Butler, H J, Hegarty, M G, Brennan, P M, Jenkinson, M D, Syed, K, Ashton, K M, Dawson, T P, Palmer, D S & Baker, M J 2020, ' Stratifying Brain Tumour Histological Sub-Types: The Application of ATR-FTIR Serum Spectroscopy in Secondary Care ', Cancers, vol. 12, no. 7, pp. 1710 . https://doi.org/10.3390/cancers12071710
Volume 12
Issue 7
Cancers
Cameron, J M, Rinaldi, C, Butler, H J, Hegarty, M G, Brennan, P M, Jenkinson, M D, Syed, K, Ashton, K M, Dawson, T P, Palmer, D S & Baker, M J 2020, ' Stratifying Brain Tumour Histological Sub-Types: The Application of ATR-FTIR Serum Spectroscopy in Secondary Care ', Cancers, vol. 12, no. 7, pp. 1710 . https://doi.org/10.3390/cancers12071710
Volume 12
Issue 7
Patients living with brain tumours have the highest average years of life lost of any cancer, ultimately reducing average life expectancy by 20 years. Diagnosis depends on brain imaging and most often confirmatory tissue biopsy for histology. The maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53ff7eeeebf314d35e21a99ed425282
https://www.mdpi.com/2072-6694/12/7/1710
https://www.mdpi.com/2072-6694/12/7/1710
Autor:
Holly J. Butler, Khaja Syed, Paul Brennan, James Cameron, Timothy Dawson, Katherine M. Ashton, Michael D. Jenkinson, Benjamin R. Smith, Mark G. Hegarty, Matthew J. Baker, David S. Palmer
Publikováno v:
The Analyst
Cameron, J M, Butler, H J, Smith, B R, Hegarty, M G, Jenkinson, M D, Syed, K, Brennan, P M, Ashton, K, Dawson, T, Palmer, D S & Baker, M J 2019, ' Developing infrared spectroscopic detection for stratifying brain tumour patients: glioblastoma multiforme vs. lymphoma ', Analyst, vol. 144, no. 22, pp. 6736-6750 . https://doi.org/10.1039/C9AN01731C
Cameron, J M, Butler, H J, Smith, B R, Hegarty, M G, Jenkinson, M D, Syed, K, Brennan, P M, Ashton, K, Dawson, T, Palmer, D S & Baker, M J 2019, ' Developing infrared spectroscopic detection for stratifying brain tumour patients: glioblastoma multiforme vs. lymphoma ', Analyst, vol. 144, no. 22, pp. 6736-6750 . https://doi.org/10.1039/C9AN01731C
Over a third of brain tumour patients visit their general practitioner more than five times prior to diagnosis in the UK, leading to 62% of patients being diagnosed as emergency presentations. Unfortunately, symptoms are non-specific to brain tumours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7621eb8443b6dcfc44dc41da82cb06dd
http://livrepository.liverpool.ac.uk/3069377/1/2019_Analyst_JMC.docx
http://livrepository.liverpool.ac.uk/3069377/1/2019_Analyst_JMC.docx
Autor:
Benjamin R. Smith, Holly J. Butler, Paul Brennan, James Cameron, David S. Palmer, Michael D. Jenkinson, Duncan Finlayson, Mark G. Hegarty, Matthew J. Baker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Butler, H J, Brennan, P M, Cameron, J M, Finlayson, D, Hegarty, M G, Jenkinson, M D, Palmer, D S, Smith, B R & Baker, M J 2019, ' Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer ', Nature Communications, vol. 10, 4501 . https://doi.org/10.1038/s41467-019-12527-5
Nature Communications
Butler, H J, Brennan, P M, Cameron, J M, Finlayson, D, Hegarty, M G, Jenkinson, M D, Palmer, D S, Smith, B R & Baker, M J 2019, ' Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer ', Nature Communications, vol. 10, 4501 . https://doi.org/10.1038/s41467-019-12527-5
Non-specific symptoms, as well as the lack of a cost-effective test to triage patients in primary care, has resulted in increased time-to-diagnosis and a poor prognosis for brain cancer patients. A rapid, cost-effective, triage test could significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81389fa4fa3c57ed9ea1209e4b16b33
https://doi.org/10.1038/s41467-019-12527-5
https://doi.org/10.1038/s41467-019-12527-5
Autor:
Helen Caldwell, Justin J. A. Conn, Paul Brennan, Gianfelice Cinque, David S. Palmer, Christopher Rinaldi, Michael D. Jenkinson, Matthew J. Baker, Holly J. Butler, James Cameron, Khaja Syed, Mark G. Hegarty, Alexandra Sala
Publikováno v:
Cancers, Vol 12, Iss 3682, p 3682 (2020)
Cameron, J M, Conn, J J A, Rinaldi, C, Sala, A, Brennan, P M, Jenkinson, M D, Caldwell, H, Cinque, G, Syed, K, Butler, H J, Hegarty, M G, Palmer, D S & Baker, M J 2020, ' Interrogation of IDH1 Status in Gliomas by Fourier Transform Infrared Spectroscopy ', Cancers, vol. 12, no. 12, pp. 3682 . https://doi.org/10.3390/cancers12123682
Cancers
Volume 12
Issue 12
Cameron, J M, Conn, J J A, Rinaldi, C, Sala, A, Brennan, P M, Jenkinson, M D, Caldwell, H, Cinque, G, Syed, K, Butler, H J, Hegarty, M G, Palmer, D S & Baker, M J 2020, ' Interrogation of IDH1 Status in Gliomas by Fourier Transform Infrared Spectroscopy ', Cancers, vol. 12, no. 12, pp. 3682 . https://doi.org/10.3390/cancers12123682
Cancers
Volume 12
Issue 12
Simple Summary Gliomas represent the vast majority of primary brain tumours and are of significant medical importance due to the poor clinical course of affected patients. The isocitrate dehydrogenase 1 (IDH1) mutation is associated with improved pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e6db757a29b36e4adc041950de824e
https://doi.org/10.3390/cancers12123682
https://doi.org/10.3390/cancers12123682