Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mark G. Carter"'
Publikováno v:
Stem Cells International, Vol 2011 (2011)
Externí odkaz:
https://doaj.org/article/9e2d02e0b91646b5a783bfed8d8b6916
Autor:
Cynthia C. Bamdad, Benoit J. Smagghe, Mark G. Carter, Trevor J. Grant, Laura M. Reale, Michael J. Nash, Danica M. Walkley, Jac-Leen S. Nash, Kevin R. Yi, Andrew K. Stewart
Publikováno v:
Cancer Research. 83:2487-2487
Purpose: To develop therapeutics to treat metastasis of solid tumor cancers. To overcome obstacles to developing anti-metastasis treatments by: 1) developing an animal model that reproducibly mimics cancer metastasis and does so within a reasonable t
Autor:
Cynthia Carol Bamdad, Benoit J. Smagghe, Mark G. Carter, Trevor J. Grant, Danica M. Page, Laura M. Reale, Michael J. Nash, Jac-Leen S. Nash, Andrew K. Stewart
Publikováno v:
Cancer Research. 82:3458-3458
Purpose: To develop an antibody therapeutic that disrupts interaction between onco-embryonic growth factor NME7AB and its cognate growth factor receptor, MUC1*, for the treatment of solid tumors and inhibition of their metastases. Normally, NME7 is o
Autor:
Cynthia Carol Bamdad, Yuan Yuan, Jennifer M. Specht, Andrew K. Stewart, Benoit J. Smagghe, Stephen Chi-Min Lin, Mark G. Carter, Timothy W. Synold, Paul Henry Frankel, Vishwas Parekh, Danica M. Walkley, L Elizabeth Budde, Qing Liu-Michael, Jac-Leen Nash, Michael J. Nash, Laura M. Reale, Kevin Y. Yi, Teresa Kim, Stanley R. Hamilton, Stephen J. Forman
Publikováno v:
Journal of Clinical Oncology. 40:TPS1130-TPS1130
TPS1130 Background: Metastatic breast cancer (MBC) remains incurable and novel immunotherapy for durable response remains an unmet need. Chimeric antigen receptor (CAR) T-cell therapy, an innovative form of immunotherapy wherein autologous T-cells ar
Autor:
Mark G. Carter, Cynthia Bamdad, Trevor J. Grant, Tyler E. Swanson, Jennifer M. Specht, Benoit J. Smagghe, Andrew K. Stewart, Pengyu Huang, Danica M. Page
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Minerva Biotechnologies has opened a Phase I 1st-in-human CAR T clinical trial, NCT-04020575, for metastatic breast cancers at the Fred Hutchinson Cancer Research Center. huMNC2-CAR44 targets the truncated extra cellular domain of MUC1* (m
Autor:
Ryo Matoba, Hitoshi Niwa, Shinji Masui, Satoshi Ohtsuka, Mark G Carter, Alexei A Sharov, Minoru S H Ko
Publikováno v:
PLoS ONE, Vol 1, p e26 (2006)
POU transcription factor Pou5f1 (Oct3/4) is required to maintain ES cells in an undifferentiated state. Here we show that global expression profiling of Oct3/4-manipulated ES cells delineates the downstream target genes of Oct3/4. Combined with data
Externí odkaz:
https://doaj.org/article/26535a3342844d86bf0a9febcfbaac56
Autor:
Alexei A Sharov, Yulan Piao, Ryo Matoba, Dawood B Dudekula, Yong Qian, Vincent VanBuren, Geppino Falco, Patrick R Martin, Carole A Stagg, Uwem C Bassey, Yuxia Wang, Mark G Carter, Toshio Hamatani, Kazuhiro Aiba, Hidenori Akutsu, Lioudmila Sharova, Tetsuya S Tanaka, Wendy L Kimber, Toshiyuki Yoshikawa, Saied A Jaradat, Serafino Pantano, Ramaiah Nagaraja, Kenneth R Boheler, Dennis Taub, Richard J Hodes, Dan L Longo, David Schlessinger, Jonathan Keller, Emily Klotz, Garnett Kelsoe, Akihiro Umezawa, Angelo L Vescovi, Janet Rossant, Tilo Kunath, Brigid L M Hogan, Anna Curci, Michele D'Urso, Janet Kelso, Winston Hide, Minoru S H Ko
Publikováno v:
PLoS Biology, Vol 1, Iss 3, p E74 (2003)
Understanding and harnessing cellular potency are fundamental in biology and are also critical to the future therapeutic use of stem cells. Transcriptome analysis of these pluripotent cells is a first step towards such goals. Starting with sources th
Externí odkaz:
https://doaj.org/article/1708d315f6714b659334ba91f551e95e
Autor:
Mark G. Carter, Ren-He Xu, Chul Kim, Ge Lin, Joonghoon Park, Xiuchun Cindy Tian, Tomokazu Amano
Publikováno v:
Cellular Reprogramming. 14:1-7
The efficiency of embryonic stem (ES) cell derivation relies on an optimized culture medium and techniques for treating preimplantation stage embryos. Recently, ES cell derivation from the preblastocyst developmental stage was reported by removing th
Autor:
Nathalie Boucher, Jason D. Gibson, Craig E. Nelson, Mark G. Carter, Kelly A. Holbrook, Caroline M. Jakuba
Publikováno v:
Integrative Biology. 1:540-551
We demonstrate the qualitative and quantitative power of single-cell transcript analysis to characterize transcriptome dynamics in human embryonic stem cells (hESC's). Single-cell analysis can systematically determine unique cellular profiles for use
Autor:
Lin Liu, Chao Li, Tomokazu Amano, Chao Wu, Shanbo Cao, Zhisheng Chen, Junjiu Huang, Zhong Liu, Lingjun Zhou, Xiangzhong Yang, Mark G. Carter, Bodu Liu, David L. Keefe
Publikováno v:
Stem Cells. 27:2136-2145
Mammalian parthenogenetic embryos are not viable and die because of defects in placental development and genomic imprinting. Parthenogenetic ESCs (pESCs) derived from parthenogenetic embryos might advance regenerative medicine by avoiding immuno-reje