Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mark G. Atherton"'
Autor:
Anthony V. Moorman, Hazel M. Robinson, F W van Delft, Helen Worley, Christine J. Harrison, Sarah Wright, Jonathan C. Strefford, G Bettney, Fiona M. Ross, Vaskar Saha, Teresa Davies, Adam R. M. Stewart, Sandra Hing, Polly Talley, Mike Griffiths, Mark G. Atherton, Kerry E. Barber
Publikováno v:
Oncogene. 26(29)
Chromosomal abnormalities are important for the classification and risk stratification of patients with acute lymphoblastic leukemia (ALL). However, approximately 30% of childhood and 50% of adult patients lack abnormalities with clinical relevance.
Autor:
Florence Nguyen-Khac, Debra M. Lillington, Lana Harder, Theodore Balasas, E. Loraine Karran, Aneela Majid, Stéphanie Struski, Mark G. Atherton, Polly Talley, María José Calasanz, Jonathan C. Strefford, Renata Walewska, Helen Worley, Anne Hagemeijer, Isabelle Radford-Weiss, José I. Martín-Subero, Keiji Sugimoto, Helena Kempski, Melanie J. Welham, Michel Lessard, Takashi Akasaka, Teresa Davies, Sarah Moore, Oskar A. Haas, Christine J. Harrison, David Brown, Claudia Schoch, Reiner Siebert, Monika Brüggemann, Lisa J. Russell, Martin J. S. Dyer, Stefan Gesk, Kelvin Cain
Publikováno v:
Blood. 109(8)
CCAAT enhancer-binding protein (CEBP) transcription factors play pivotal roles in proliferation and differentiation, including suppression of myeloid leukemogenesis. Mutations of CEBPA are found in a subset of acute myeloid leukemia (AML) and in some
Autor:
Andrew R. Pettitt, Angela Douglas, Anna Burford, Paul D. Sherrington, Anthony Carter, Kevin Pearson, Ke Lin, Mark G. Atherton, Daniel Catovsky, Vasantha Brito-Babapulle, Estella Matutes
Publikováno v:
Blood. 104:953-953
Adverse prognostic factors in CLL include functional impairment of the p53 pathway [Blood2002;100:1404] and the chromosomal aberrations del 17p13, del 11q23 and +12 [reviewed in Leukemia2002;16:993]. Intriguingly, TP53 is deleted at 17p13, ATM (an im