Benchmarking of human Y-chromosomal haplogroup classifiers with whole-genome and whole-exome sequence data

Autor: Víctor García-Olivares, Adrián Muñoz-Barrera, Luis A. Rubio-Rodríguez, David Jáspez, Ana Díaz-de Usera, Antonio Iñigo-Campos, Krishna R. Veeramah, Santos Alonso, Mark G. Thomas, José M. Lorenzo-Salazar, Rafaela González-Montelongo, Carlos Flores

Publikováno v: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4613-4618 (2023)

In anthropological, medical, and forensic studies, the nonrecombinant region of the human Y chromosome (NRY) enables accurate reconstruction of pedigree relationships and retrieval of ancestral information. Using high-throughput sequencing (HTS) data

Externí odkaz: https://doaj.org/article/981f9a74af5c417c9373fe2494ec5bbc

Evidence of the interplay of genetics and culture in Ethiopia

Autor: Saioa López, Ayele Tarekegn, Gavin Band, Lucy van Dorp, Nancy Bird, Sam Morris, Tamiru Oljira, Ephrem Mekonnen, Endashaw Bekele, Roger Blench, Mark G. Thomas, Neil Bradman, Garrett Hellenthal

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Ethiopia is one of the most ethnically and culturally diverse countries. Here, the authors look at genetic and cultural variation in 1,214 Ethiopians to unravel the relationship between genetic admixture and cultural factors.

Externí odkaz: https://doaj.org/article/767ca36ad41e472ab92f764a62270499

Impact of a smartphone app on prescriber adherence to antibiotic guidelines in adult patients with community acquired pneumonia or urinary tract infections.

Autor: Chang Ho Yoon, Stephen R Ritchie, Eamon J Duffy, Mark G Thomas, Stephen McBride, Kerry Read, Rachel Chen, Gayl Humphrey

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0211157 (2019)

BACKGROUND:Mobile phone apps have been shown to enhance guideline adherence by prescribers, but have not been widely evaluated for their impact on guideline adherence by prescribers caring for inpatients with infections. OBJECTIVES:To determine wheth

Externí odkaz: https://doaj.org/article/56c69159aee745b0a2e250c51d75d3d3

Intravenous opioids for chemotherapy‐induced severe mucositis pain in children: Systematic review and single‐center case series of management with patient‐ or nurse‐controlled analgesia (PCA/NCA)

Autor: Judy Peters, Ebony L. Selers, Suellen M. Walker, Judith Middleton, Richard F. Howard, Mark G. Thomas, Muhammad Farhad Islam, Hayley McKenna, Kuan Ooi, Kirsty Keen, Reema Nandi, Matthew A Jay, Fiona Richards, Becky Saul, Glyn Williams, Elizabeth Robinson, Claire Vanstock, Suzanne Lilley

Publikováno v: Pediatric Anesthesia. 32:17-34

BACKGROUND Chemotherapy-induced oral mucositis can result in severe pain. Intravenous (IV) opioids are recommended, but management protocols vary. We systematically reviewed studies reporting IV opioid use for pain related to chemotherapy-induced sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f93130f14d903d646158275bee9df0
https://doi.org/10.1111/pan.14324

The Anglo-Saxon migration and the formation of the early English gene pool

Autor: Joscha Gretzinger, Duncan Sayer, Pierre Justeau, Eveline Altena, Maria Pala, Katharina Dulias, Ceiridwen J. Edwards, Susanne Jodoin, Laura Lacher, Susanna Sabin, Åshild J. Vågene, Wolfgang Haak, S. Sunna Ebenesersdóttir, Kristjan H. S. Moore, Rita Radzeviciute, Kara Schmidt, Selina Brace, Martina Abenhus Bager, Nick Patterson, Luka Papac, Nasreen Broomandkhoshbacht, Kimberly Callan, Éadaoin Harney, Lora Iliev, Ann Marie Lawson, Megan Michel, Kristin Stewardson, Fatma Zalzala, Nadin Rohland, Stefanie Kappelhoff-Beckmann, Frank Both, Daniel Winger, Daniel Neumann, Lars Saalow, Stefan Krabath, Sophie Beckett, Melanie Van Twest, Neil Faulkner, Chris Read, Tabatha Barton, Joanna Caruth, John Hines, Ben Krause-Kyora, Ursula Warnke, Verena J. Schuenemann, Ian Barnes, Hanna Dahlström, Jane Jark Clausen, Andrew Richardson, Elizabeth Popescu, Natasha Dodwell, Stuart Ladd, Tom Phillips, Richard Mortimer, Faye Sayer, Diana Swales, Allison Stewart, Dominic Powlesland, Robert Kenyon, Lilian Ladle, Christina Peek, Silke Grefen-Peters, Paola Ponce, Robin Daniels, Cecily Spall, Jennifer Woolcock, Andy M. Jones, Amy V. Roberts, Robert Symmons, Anooshka C. Rawden, Alan Cooper, Kirsten I. Bos, Tom Booth, Hannes Schroeder, Mark G. Thomas, Agnar Helgason, Martin B. Richards, David Reich, Johannes Krause, Stephan Schiffels

Publikováno v: Nature
Gretzinger, J, Sayer, D, Justeau, P, Altena, E, Pala, M, Dulias, K, Edwards, C J, Jodoin, S, Lacher, L, Sabin, S, Vågene, Å J, Haak, W, Ebenesersdóttir, S S, Moore, K H S, Radzeviciute, R, Schmidt, K, Brace, S, Bager, M A, Patterson, N, Papac, L, Broomandkhoshbacht, N, Callan, K, Harney, É, Iliev, L, Lawson, A M, Michel, M, Stewardson, K, Zalzala, F, Rohland, N, Kappelhoff-Beckmann, S, Both, F, Winger, D, Neumann, D, Saalow, L, Krabath, S, Beckett, S, Van Twest, M, Faulkner, N, Read, C, Barton, T, Caruth, J, Hines, J, Krause-Kyora, B, Warnke, U, Schuenemann, V J, Barnes, I, Dahlström, H, Clausen, J J, Richardson, A, Popescu, E, Dodwell, N, Ladd, S, Phillips, T, Mortimer, R, Sayer, F, Swales, D, Stewart, A, Powlesland, D, Kenyon, R, Ladle, L, Peek, C, Grefen-Peters, S, Ponce, P, Daniels, R, Spall, C, Woolcock, J, Jones, A M, Roberts, A V, Symmons, R, Rawden, A C, Cooper, A, Bos, K I, Booth, T, Schroeder, H, Thomas, M G, Helgason, A, Richards, M B, Reich, D, Krause, J & Schiffels, S 2022, ' The Anglo-Saxon migration and the formation of the early English gene pool ', Nature, vol. 610, pp. 112-119 . https://doi.org/10.1038/s41586-022-05247-2
Nature, 610(7930), 112-+. NATURE PORTFOLIO

The history of the British Isles and Ireland is characterized by multiple periods of major cultural change, including the influential transformation after the end of Roman rule, which precipitated shifts in language, settlement patterns and material

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5be5e57f72b6a17148e0cefd0aa7636
https://eprints.bournemouth.ac.uk/37579/1/s41586-022-05247-2.pdf