Výsledky vyhledávání - "Mark G Delboy"

Akademický článek

Widely Used Herpes Simplex Virus 1 ICP0 Deletion Mutant Strain dl1403 and Its Derivative Viruses Do Not Express Glycoprotein C Due to a Secondary Mutation in the gC Gene.

Autor: Cristina W Cunha, Kathryne E Taylor, Suzanne M Pritchard, Mark G Delboy, Tri Komala Sari, Hector C Aguilar, Karen L Mossman, Anthony V Nicola

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0131129 (2015)

Herpes simplex virus 1 (HSV-1) ICP0 is a multi-functional phosphoprotein expressed with immediate early kinetics. An ICP0 deletion mutant, HSV-1 dl1403, has been widely used to study the roles of ICP0 in the HSV-1 replication cycle including gene exp

Externí odkaz: https://doaj.org/article/1934340ecbc34161a73185b40e63238d

Zobrazit plný text záznamu

Defining Influenza A Virus Hemagglutinin Antigenic Drift by Sequential Monoclonal Antibody Selection

Autor: Jack R. Bennink, Christopher B. Brooke, James S. Gibbs, Gustáv Russ, William L. Ince, Mark G. Delboy, Anju Subba, Scott E. Hensley, Suman R. Das, Jonathan W. Yewdell

Publikováno v: Cell Host & Microbe. 13(3):314-323

SummaryHuman influenza A virus (IAV) vaccination is limited by “antigenic drift,” rapid antibody-driven escape reflecting amino acid substitutions in the globular domain of hemagglutinin (HA), the viral attachment protein. To better understand dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc284a966b0e2a8c457dd8dcb773b51

Zobrazit plný text záznamu

A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus

Autor: Anthony V. Nicola, Mark G. Delboy

Publikováno v: Journal of Virology

Herpes simplex virus (HSV) entry requires host cell 26S proteasomal degradation activity at a postpenetration step. When expressed in the infected cell, the HSV immediate-early protein ICP0 has E3 ubiquitin ligase activity and interacts with the prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2188022abbc2f62f24d257094e525f19

Zobrazit plný text záznamu

Herpes Simplex Virus Tegument ICP0 Is Capsid Associated, and Its E3 Ubiquitin Ligase Domain Is Important for Incorporation into Virions

Autor: Carlos R. Siekavizza-Robles, Anthony V. Nicola, Mark G. Delboy

Publikováno v: Journal of Virology. 84:1637-1640

Herpes simplex virus (HSV) immediate-early (IE) protein ICP0 is a multifunctional regulator of HSV infection. ICP0 that is present in the tegument layer has not been well characterized. Protein compositions of wild-type and ICP0 null virions were sim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39ab8685e2f194a20e643e869a83b1f
https://doi.org/10.1128/jvi.02041-09

Zobrazit plný text záznamu

Cellular Proteasome Activity Facilitates Herpes Simplex Virus Entry at a Postpenetration Step

Autor: Devin G. Roller, Anthony V. Nicola, Mark G. Delboy

Publikováno v: Journal of Virology. 82:3381-3390

Herpes simplex virus (HSV) entry into cells is a multistep process that engages the host cell machinery. The proteasome is a large, ATP-dependent, multisubunit protease that plays a critical role in the maintenance of cell homeostasis. A battery of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc08f931c79dac4ab04a348e5efd052
https://doi.org/10.1128/jvi.02296-07

Zobrazit plný text záznamu

Low pH-induced conformational change in herpes simplex virus glycoprotein B

Autor: Stephen J. Dollery, Anthony V. Nicola, Mark G. Delboy

Publikováno v: Journal of Virology

Herpesviruses can enter host cells using pH-dependent endocytosis pathways in a cell-specific manner. Envelope glycoprotein B (gB) is conserved among all herpesviruses and is a critical component of the complex that mediates membrane fusion and entry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0936c089e5381f20416065182fd8590b
https://pubmed.ncbi.nlm.nih.gov/20147407

Zobrazit plný text záznamu

Role of the UL45 protein in herpes simplex virus entry via low pH-dependent endocytosis and its relationship to the conformation and function of glycoprotein B

Autor: Anthony V. Nicola, Devin G. Roller, Kristin D. Lane, Stephen J. Dollery, Mark G. Delboy

Herpesviruses commandeer distinct cellular pathways to enter target cells. The mechanism by which herpes simplex virus (HSV) selects a pH-dependent, endocytic route or a pH-independent route remains to be elucidated. We investigated the role of the n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63c04e40718a29c468ddcc17965f7b4
https://europepmc.org/articles/PMC2834853/

Zobrazit plný text záznamu

Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells

Autor: Aimee M. Hollander, Mark G Delboy, Anthony V Nicola, Jennifer L. Patterson

Publikováno v: Virology Journal, Vol 3, Iss 1, p 105 (2006)
Virology Journal

Background Herpes simplex virus (HSV) can utilize multiple pathways to enter host cells. The factors that determine which route is taken are not clear. Chinese hamster ovary (CHO) cells that express glycoprotein D (gD)-binding receptors are model cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14ecbe9e9b527081b3471ee656fc1b9
http://www.virologyj.com/content/3/1/105

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání