Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mark Frerker"'
Autor:
Kyle T. Siebenthall, Chris P. Miller, Jeff D. Vierstra, Julie Mathieu, Maria Tretiakova, Alex Reynolds, Richard Sandstrom, Eric Rynes, Eric Haugen, Audra Johnson, Jemma Nelson, Daniel Bates, Morgan Diegel, Douglass Dunn, Mark Frerker, Michael Buckley, Rajinder Kaul, Ying Zheng, Jonathan Himmelfarb, Hannele Ruohola-Baker, Shreeram Akilesh
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 427-442 (2019)
Background: Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transc
Externí odkaz:
https://doaj.org/article/829eb39cb4bc4574ad67b01c5d08b888
Autor:
Benjamin C. Hitz, Jin-Wook Lee, Otto Jolanki, Meenakshi S. Kagda, Keenan Graham, Paul Sud, Idan Gabdank, J. Seth Strattan, Cricket A. Sloan, Timothy Dreszer, Laurence D. Rowe, Nikhil R. Podduturi, Venkat S. Malladi, Esther T. Chan, Jean M. Davidson, Marcus Ho, Stuart Miyasato, Matt Simison, Forrest Tanaka, Yunhai Luo, Ian Whaling, Eurie L. Hong, Brian T. Lee, Richard Sandstrom, Eric Rynes, Jemma Nelson, Andrew Nishida, Alyssa Ingersoll, Michael Buckley, Mark Frerker, Daniel S Kim, Nathan Boley, Diane Trout, Alex Dobin, Sorena Rahmanian, Dana Wyman, Gabriela Balderrama-Gutierrez, Fairlie Reese, Neva C. Durand, Olga Dudchenko, David Weisz, Suhas S. P. Rao, Alyssa Blackburn, Dimos Gkountaroulis, Mahdi Sadr, Moshe Olshansky, Yossi Eliaz, Dat Nguyen, Ivan Bochkov, Muhammad Saad Shamim, Ragini Mahajan, Erez Aiden, Tom Gingeras, Simon Heath, Martin Hirst, W. James Kent, Anshul Kundaje, Ali Mortazavi, Barbara Wold, J. Michael Cherry
The Encyclopedia of DNA elements (ENCODE) project is a collaborative effort to create a comprehensive catalog of functional elements in the human genome. The current database comprises more than 19000 functional genomics experiments across more than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ede3b75e1612917e82c16d5ca40cfb
https://doi.org/10.1101/2023.04.04.535623
https://doi.org/10.1101/2023.04.04.535623
Autor:
John A. Stamatoyannopoulos, Mark Frerker, Kristen Lee, Eric Rynes, Douglas Dunn, Michael Buckley, Wouter Meuleman, Fidencio Neri, Athanasios Teodosiadis, Daniel Bates, J. K. Nelson, Alexander L. Muratov, Alex Reynolds, Eric Haugen, Richard Sandstrom, Rajinder Kaul, Morgan Diegel, Jeff Vierstra, Audra K. Johnson, Jessica Halow
Publikováno v:
Nature
DNase I hypersensitive sites (DHSs) are generic markers of regulatory DNA1–5 and contain genetic variations associated with diseases and phenotypic traits6–8. We created high-resolution maps of DHSs from 733 human biosamples encompassing 438 cell
Autor:
Daniel Bates, Michael Buckley, Mark Frerker, Morgan Diegel, Rajinder Kaul, Eric Rynes, Audra K. Johnson, Alex Reynolds, Eric Haugen, J. K. Nelson, John A. Stamatoyannopoulos, Jessica Halow, Kristen Lee, Fidencio Neri, John Lazar, Douglas Dunn, Wouter Meuleman, Richard Sandstrom, Jeff Vierstra
Publikováno v:
Nature
Combinatorial binding of transcription factors to regulatory DNA underpins gene regulation in all organisms. Genetic variation in regulatory regions has been connected with diseases and diverse phenotypic traits1, but it remains challenging to distin
Autor:
Julie Mathieu, Daniel Bates, Kyle Siebenthall, Maria S. Tretiakova, Hannele Ruohola-Baker, Douglas Dunn, Eric Haugen, Jeff Vierstra, Alex Reynolds, Audra K. Johnson, J. K. Nelson, Michael Buckley, Eric Rynes, Yingye Zheng, Rajinder Kaul, Mark Frerker, Richard Sandstrom, Jonathan Himmelfarb, Chris P. Miller, Morgan Diegel, Shreeram Akilesh
Publikováno v:
EBioMedicine
Background Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transcr
Autor:
Wouter Meuleman, Eric Rynes, Alex Reynolds, Morgan Diegel, Rajinder Kaul, Jeff Vierstra, J. K. Nelson, Douglas Dunn, Jessica Halow, Kristen Lee, Daniel Bates, John A. Stamatoyannopoulos, Audra K. Johnson, Fidencio Neri, Richard Sandstrom, John Lazar, Mark Frerker, Michael Buckley, Eric Haugen
Combinatorial binding of transcription factors to regulatory DNA underpins gene regulation in all organisms. Genetic variation in regulatory regions has been connected with diseases and diverse phenotypic traits1, yet it remains challenging to distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01bbd6941deac7bf95f6f912f255e75
Autor:
Hannele Ruohola-Baker, Shreeram Akilesh, Mark Frerker, Jeff Vierstra, Shane Neph, Jonathan Himmelfarb, Daniel Bates, Richard Sandstrom, Eric Haugen, Chris P. Miller, Julie Mathieu, J. K. Nelson, Maria S. Tretiakova, Morgan Diegel, Yingye Zheng, Audra K. Johnson, Eric Rynes, Kyle Siebenthall, Douglas Dunn, Michael Buckley, Rajinder Kaul, Alex Reynolds
Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. As a model system, we used renal cell carcinoma (RCC), the most common malignant kidney tumor which canonically activates the hypoxia-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74d23ef2875019948cea45cc7dc8fa9