Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mark Fedesco"'
Autor:
Aadithya Kannan, Michael Chinn, Saeed Izadi, Andrew Maier, James Dvornicky, Mark Fedesco, Eric Day, Asif Ladiwala, Ann Woys
Publikováno v:
Journal of pharmaceutical sciences.
In the manufacturing of therapeutic monoclonal antibodies (mAbs), the final steps of the purification process are typically ultrafiltration/diafiltration (UF/DF), dilution, and conditioning. These steps are developed such that the final drug substanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052fc350c1a955bd6ea3a5d7411b42a0
https://pubmed.ncbi.nlm.nih.gov/36336103
https://pubmed.ncbi.nlm.nih.gov/36336103
Publikováno v:
Journal of chromatography. A. 1666
The development of manufacturing processes for antibody-drug conjugates (ADCs) presents many challenges compared to a standard monoclonal antibody. Conjugation processes typically start with an antibody intermediate that was purified to have very low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d5c4305bcaab2505bc578c6d9abe10
https://pubmed.ncbi.nlm.nih.gov/35131516
https://pubmed.ncbi.nlm.nih.gov/35131516
Autor:
Camille L. Bilodeau, Giorgio Carta, Eric von Lieres, Steve Benner, Deenesh Kavi Babi, Philipp Ernst, Oleksandr Zavalov, John P. Welsh, Jan Griesbach, Marcel Stenvang, Larry Sun, Ernst Broberg Hansen, Arne Staby, S. Hunt, Thomas Wucherpfennig, Emmanouil Papadakis, Dilip Asthagiri, Matthew Flamm, Mark Fedesco, Sean Fitzgibbon, Bruno F. Marques, David J. Roush, Jasper C. Lin, Richard C. Willson, Fabrice Schlegel, Francis Insaidoo, Henrik S. Marke, Gang Wang, Tobias Grosskopf, Abraham M. Lenhoff, Peter M. Tessier, Tobias Hahn, R. Todd
Publikováno v:
Biotechnology & bioengineering 117(12), 3986-4000 (2020). doi:10.1002/bit.27520
The Third Modeling Workshop focusing on bioprocess modeling was held in Kenilworth, NJ in May 2019. A summary of these Workshop proceedings is captured in this manuscript. Modeling is an active area of research within the biotechnology community, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439240129d8f91f7f1d2274d485c9aa6
https://hdl.handle.net/2128/27001
https://hdl.handle.net/2128/27001
Publikováno v:
Biotechnology progress. 31(1)
Incorporation of norleucine in place of methionine residues during recombinant protein production in Escherichia coli is well known. Continuous feeding of methionine is commonly used in E. coli recombinant protein production processes to prevent norl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374b46ed1286db5a66d014984038b4ed
https://pubmed.ncbi.nlm.nih.gov/25315437
https://pubmed.ncbi.nlm.nih.gov/25315437