Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Mark F. Mehler"'
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionNeurocognitive symptoms and dysfunction of various severities have become increasingly recognized as potential consequences of SARS-CoV-2 infection. Although there are numerous observational and subjective survey-reporting studies of neur
Externí odkaz:
https://doaj.org/article/19767f06edf74d6082e80441bb5347a6
Autor:
Aristea S. Galanopoulou, Victor Ferastraoaru, Daniel J. Correa, Koshi Cherian, Susan Duberstein, Jonathan Gursky, Rajani Hanumanthu, Christine Hung, Isaac Molinero, Olga Khodakivska, Alan D. Legatt, Puja Patel, Jillian Rosengard, Elayna Rubens, William Sugrue, Elissa Yozawitz, Mark F. Mehler, Karen Ballaban‐Gil, Sheryl R. Haut, Solomon L. Moshé, Alexis Boro
Publikováno v:
Epilepsia Open, Vol 5, Iss 2, Pp 314-324 (2020)
Abstract Objective Acute encephalopathy may occur in COVID‐19‐infected patients. We investigated whether medically indicated EEGs performed in acutely ill patients under investigation (PUIs) for COVID‐19 report epileptiform abnormalities and wh
Externí odkaz:
https://doaj.org/article/ab80b2f726c845ce95baa8c698c89598
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
SARS-CoV-2 infection is associated with a spectrum of acute neurological syndromes. A subset of these syndromes promotes higher in-hospital mortality than is predicted by traditional parameters defining critical care illness. This suggests that dereg
Externí odkaz:
https://doaj.org/article/836c668a24c04aef80508a7fa54f1942
Autor:
Irfan A. Qureshi, Mark F. Mehler
Publikováno v:
Neurobiology of Disease, Vol 153, Iss , Pp 105333- (2021)
Externí odkaz:
https://doaj.org/article/6b4d3e65f5044f00a964df9e7f7c227b
Autor:
Violeta Chitu, Fabrizio Biundo, Gabriel G.L. Shlager, Eun S. Park, Ping Wang, Maria E. Gulinello, Şölen Gokhan, Harmony C. Ketchum, Kusumika Saha, Michael A. DeTure, Dennis W. Dickson, Zbignew K. Wszolek, Deyou Zheng, Andrew L. Croxford, Burkhard Becher, Daqian Sun, Mark F. Mehler, E. Richard Stanley
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3004-3019.e5 (2020)
Summary: CSF-1R haploinsufficiency causes adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). Previous studies in the Csf1r+/− mouse model of ALSP hypothesized a central role of elevated cerebral Csf2 expression. Here,
Externí odkaz:
https://doaj.org/article/42236b5881c04b5fa22179d897b5e04f
Autor:
Eduardo E. Arteaga-Bracho, Maria Gulinello, Michael L. Winchester, Nandini Pichamoorthy, Jenna R. Petronglo, Alicia D. Zambrano, Julio Inocencio, Chirstopher D. De Jesus, Joseph O. Louie, Solen Gokhan, Mark F. Mehler, Aldrin E. Molero
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 144-155 (2016)
The mutation in huntingtin (mHtt) leads to a spectrum of impairments in the developing forebrain of Huntington's disease (HD) mouse models. Whether these developmental alterations are due to loss- or gain-of-function mechanisms and contribute to HD p
Externí odkaz:
https://doaj.org/article/033914eac2624c8087987ee040422140
Autor:
Violeta Chitu, Solen Gokhan, Maria Gulinello, Craig A. Branch, Madhuvati Patil, Ranu Basu, Corrina Stoddart, Mark F. Mehler, E. Richard Stanley
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 219-228 (2015)
Mutations in the colony stimulating factor-1 receptor (CSF1R) that abrogate the expression of the affected allele or lead to the expression of mutant receptor chains devoid of kinase activity have been identified in both familial and sporadic cases o
Externí odkaz:
https://doaj.org/article/2c4d223a468d435ab24276222b636ce7
Autor:
Irfan A. Qureshi, Mark F. Mehler
Publikováno v:
Neurobiology of Disease, Vol 72, Iss , Pp 210-216 (2014)
Epilepsy refers to a heterogeneous group of disorders that are associated with a wide range of pathogenic mechanisms, seizure manifestations, comorbidity profiles, and therapeutic responses. These characteristics are all influenced quite significantl
Externí odkaz:
https://doaj.org/article/566c7688e58e4ab781a136f62d07627f
Autor:
Irfan A. Qureshi, Mark F. Mehler
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 1, Pp 53-60 (2010)
The rapidly emerging science of epigenetics and epigenomic medicine promises to reveal novel insights into the susceptibility to and the onset and progression of epileptic disorders. Epigenetic regulatory mechanisms are now implicated in orchestratin
Externí odkaz:
https://doaj.org/article/10ccfc1c8bf240888fdf1d8920cd5e99
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/9fe56710d14b4e69b1c012f7d4cfa0c9