Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mark F. Ciaccio"'
Autor:
Richard Baker Jones, Shutsung Liao, Richard A. Hiipakka, Ronald J. Hause, John M. Kokontis, Mark F. Ciaccio, Hui-Ping Lin, Chih-Pin Chuu
XLS file - 14K, This file contains data from the micro-western array protein analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3447330cfde1d6feeaf318ea4a56e36
https://doi.org/10.1158/1940-6207.22523425.v1
https://doi.org/10.1158/1940-6207.22523425.v1
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44471 (2012)
First-generation interaction maps of Src homology 2 (SH2) domains with receptor tyrosine kinase (RTK) phosphosites have previously been generated using protein microarray (PM) technologies. Here, we developed a large-scale fluorescence polarization (
Externí odkaz:
https://doaj.org/article/1941f36962b34cb2a4bf527eecd278e7
Autor:
Ronald J. Hause, Amy L. Stark, Lidija K. Gorsic, Mark F. Ciaccio, Ashraf G. Madian, Vincent C. Chen, Amy L. Gill, Lida Anita To, M. Eileen Dolan, Sawyer W. Williams, Richard B. Jones, Claudia Wing, Kevin P. White, Jamie Myers
Publikováno v:
Journal of proteome research. 16(11)
Determining the effect of chemotherapeutic treatment on changes in protein expression can provide important targets for overcoming resistance. Due to challenges in simultaneously measuring large numbers of proteins, a paucity of data exists on global
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f9342a0cf3aa09b5085c433793faf8
https://pubmed.ncbi.nlm.nih.gov/28902521
https://pubmed.ncbi.nlm.nih.gov/28902521
Autor:
Mark F, Ciaccio, Richard B, Jones
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1555
The Microwestern Array (MWA) method combines the scalability and miniaturization afforded by the Reverse Phase Lysate Array (RPLA) approach with the electrophoretic separation characteristic of the Western blot. This technology emulates the creation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cef5c01a905e0f885da933f64197557
https://pubmed.ncbi.nlm.nih.gov/28092050
https://pubmed.ncbi.nlm.nih.gov/28092050
Autor:
Mark F. Ciaccio, Richard B. Jones
Publikováno v:
Methods in Molecular Biology ISBN: 9781493967605
The Microwestern Array (MWA) method combines the scalability and miniaturization afforded by the Reverse Phase Lysate Array (RPLA) approach with the electrophoretic separation characteristic of the Western blot. This technology emulates the creation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c407af8cc75b4c3a854d8893532b311
https://doi.org/10.1007/978-1-4939-6762-9_27
https://doi.org/10.1007/978-1-4939-6762-9_27
Publikováno v:
Integrative and Comparative Biology. 54:296-306
An organism's ability to maintain a desired physiological response relies extensively on how cellular and molecular signaling networks interpret and react to environmental cues. The capacity to quantitatively predict how networks respond to a changin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6eacba36fc9833fb7ac1d825616682
https://doi.org/10.1093/icb/icu037
https://doi.org/10.1093/icb/icu037
Autor:
Ronald J. Hause, John L. Barkinge, Kin K. Leung, Mark F. Ciaccio, Richard B. Jones, Chih-Pin Chuu
Publikováno v:
Molecular & Cellular Proteomics : MCP
Many human diseases are associated with aberrant regulation of phosphoprotein signaling networks. Src homology 2 (SH2) domains represent the major class of protein domains in metazoans that interact with proteins phosphorylated on the amino acid resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f37f7b03b0306eebe632a729ec23667
http://europepmc.org/articles/PMC4083110
http://europepmc.org/articles/PMC4083110
Autor:
Tanguy Y. Seiwert, Marsha Rich Rosner, Mark W. Lingen, Wen-Liang Kuo, Jing Liu, Ezra E.W. Cohen, Mark F. Ciaccio, Richard B. Jones
Publikováno v:
Head & Neck. 33:1774-1782
Background. Rapamycin is an mTOR inhibitor with preclinical efficacy in squamous cell carcinoma of the head and neck (SCCHN). However, mTOR inhibitors also increase Akt activity in SCCHN cell lines, which would promote survival and oncogenesis. Enzas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703d4417c5e5e1db6f92f3adabf38f7b
https://doi.org/10.1002/hed.21701
https://doi.org/10.1002/hed.21701
Publikováno v:
Molecular Cancer Research. 6:885-891
Although expression of the ErbB4 receptor tyrosine kinase in breast cancer is generally regarded as a marker for favorable patient prognosis, controversial exceptions have been reported. Alternative splicing of ErbB4 pre-mRNAs results in the expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ef5fc923cf165579d1e9c428181e10
https://doi.org/10.1158/1541-7786.mcr-07-0369
https://doi.org/10.1158/1541-7786.mcr-07-0369
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 7(7)
Many drug candidates fail in clinical trials due to an incomplete understanding of how small-molecule perturbations affect cell phenotype. Cellular responses can be non-intuitive due to systems-level properties such as redundant pathways caused by co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a07573c57a6afb529ef0d8c66cd39cf
https://pubmed.ncbi.nlm.nih.gov/26057728
https://pubmed.ncbi.nlm.nih.gov/26057728