Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mark F. Bean"'
Autor:
Guofeng Zhang, Enoch N Gao, Melanie Leveridge, Joseph Kozole, Carl A Machutta, Sammy S Datwani, Roland S. Annan, Arseniy M. Belov, Luke Ghislain, Mark F. Bean
Publikováno v:
Analytical Chemistry. 92:13847-13854
Drug discovery usually begins with a high-throughput screen (HTS) of thousands to millions of molecules to identify starting points for medicinal chemistry. Conventional HTS platforms require expensive reagents and typically have complex assay format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d069720ff6128efa1dd301a8f59916
https://doi.org/10.1021/acs.analchem.0c02508
https://doi.org/10.1021/acs.analchem.0c02508
Publikováno v:
Journal of Natural Products. 60:704-707
During the large-scale isolation of the batzelladines A and B, which are inhibitors of gp120-CD4 binding, we isolated 19 minor guanidine alkaloids. Three new tricyclic guanidine alkaloids isolated from this group were named 8a,8b-dehydroptilocaulin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb0d529555c4b0313af4254458a76a8
https://doi.org/10.1021/np970014r
https://doi.org/10.1021/np970014r
Autor:
Randall K. Johnson, R. Lee Webb, Alan J. Freyer, Zuber Gary Edward, Mark F. Bean, Rex Reichwein, Leo F. Faucette, Ashok D. Patil
Publikováno v:
Tetrahedron. 53:1583-1592
Bioassay-guided fractionation of the MeOH/CH2Cl2 extract of the roots of Caesalpinia pulcherrima yielded four novel dibenzoate diterpenes, pulcherrimins A, B, C and D (1–4). The structures of these compounds including their absolute configuration w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::532ba0e428a943e7e9c215de1c8b98cc
https://doi.org/10.1016/s0040-4020(96)01135-0
https://doi.org/10.1016/s0040-4020(96)01135-0
Autor:
Alemseged Truneh, W. C. M. C. Kokke, N. Vasant Kumar, Brad Carte, Charles De Brosse, Alan J. Freyer, Ashok D. Patil, Mark F. Bean, Shing Mai
Publikováno v:
The Journal of Organic Chemistry. 60:1182-1188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9f9064d039bffe15c7cf6e39de2aee
https://doi.org/10.1021/jo00110a021
https://doi.org/10.1021/jo00110a021
Publikováno v:
Journal of the American Society for Mass Spectrometry. 5:434-442
Two methods for gas phase hydrogen/deuterium exchange have been developed for the analysis of small molecules. Hydrogen/deuterium exchange has been implemented by making simple modifications to the plumbing for the nebulizer and curtain gases on a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f3bff1879051460d1df852f3e3c002
https://doi.org/10.1016/1044-0305(94)85059-3
https://doi.org/10.1016/1044-0305(94)85059-3
Publikováno v:
Protein Science. 2:183-196
A mass spectrometry method has been developed for selective detection of glycopeptides at the low (< or = 25) picomole level during chromatography of glycoprotein digests and for differentiation of O-linked from N-linked oligosaccharides. The techniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e409bd024600b43ed6f712e0678600b0
https://doi.org/10.1002/pro.5560020207
https://doi.org/10.1002/pro.5560020207
Autor:
Mark F. Bean, Steven A. Carr
Publikováno v:
Analytical Biochemistry. 201:216-226
Tandem mass spectrometry employing high-energy, collisionally activated dissociation (CAD) is shown to be a useful method for sequencing through the cystine bridge of intermolecularly disulfide-bonded peptides. A characteristic triplet of intense fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17098eba8ae0b642ccc1a641be116140
https://doi.org/10.1016/0003-2697(92)90331-z
https://doi.org/10.1016/0003-2697(92)90331-z
Publikováno v:
Analytical Chemistry. 63:2802-2824
Mass spectrometry (MS) has become an indispensable tool for peptide and protein structure analysis because of three unique capabilities that enable it to be used to solve structural problems not easily handled by conventional techniques. First, MS is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6491f9bab13ff8cc98da57303953ebd
https://doi.org/10.1021/ac00024a003
https://doi.org/10.1021/ac00024a003
Autor:
Mark F. Bean, Barbara N. Timmermann, Cecily Chambers, Terry A. Francis, Priscilla Offen, Michael J. Huddleston, John Westley, Brad Carte, Yongle Chen
Publikováno v:
Tetrahedron. 47:4869-4878
Two novel pseudoguaianolide esters, arrivacins A ( 1 ) and B ( 2 ), have been isolated from the methylene chloride extract of Ambrosia psilostachya collected in Arrivaca Cienega, Arizona. The structures of the arrivacins, which are examples of sesqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae7d3971a26990f452e1a99f9c9d7cd
https://doi.org/10.1016/s0040-4020(01)80953-4
https://doi.org/10.1016/s0040-4020(01)80953-4
Autor:
Mark F. Bean, Marie A. Harris, Steven A. Carr, Janice G. Dodd, Robert J. Matusik, Stephen E. Harris, Charles M. Johnson, John W. Crabb
Publikováno v:
Journal of Biological Chemistry. 265:9896-9903
The gene encoding rat seminal vesicle secretion II (SVS II) protein has been cloned from a rat genomic DNA library using a cDNA probe generated from rat dorsal prostate androgen-dependent mRNA. The cloned 7.3-kilobase pair genomic fragment contains a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dca707d6f616f2a53c98821c783234d2
https://doi.org/10.1016/s0021-9258(19)38756-3
https://doi.org/10.1016/s0021-9258(19)38756-3