Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mark F Swift"'
Autor:
Xiao-Ping Xu, Sabine Pokutta, Megan Torres, Mark F Swift, Dorit Hanein, Niels Volkmann, William I Weis
Publikováno v:
eLife, Vol 9 (2020)
Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton, and mechanical load strengthens its binding to F-actin in a direction
Externí odkaz:
https://doaj.org/article/7ef2fe8caae548c5b3d264ed5636d68d
Autor:
Xiao-Ping Xu, Wenxiang Cao, Mark F. Swift, Nandan G. Pandit, Andrew E. Huehn, Charles V. Sindelar, Enrique M. De La Cruz, Dorit Hanein, Niels Volkmann
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Actin filament assembly and the regulation of its mechanical properties are fundamental processes essential for eukaryotic cell function. Residue E167 in vertebrate actins forms an inter-subunit salt bridge with residue K61 of the adjacent s
Externí odkaz:
https://doaj.org/article/1d5f32e0bb794a439be8fbd9d5048e5f
Autor:
Liam P. Dow, Guido Gaietta, Yair Kaufman, Mark F. Swift, Moara Lemos, Kerry Lane, Matthew Hopcroft, Armel Bezault, Cécile Sauvanet, Niels Volkmann, Beth L. Pruitt, Dorit Hanein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Micropatterning on electron microscopy grids enables control of cell positioning and arrangement. Here, the authors describe detailed nanoscale characterization of a micropatterning workflow for reproducible molecular characterization through cryo-ET
Externí odkaz:
https://doaj.org/article/bebf45876f9a4ac5bdf2b80d63f79249
Autor:
Julien Robert-Paganin, Xiao-Ping Xu, Mark F. Swift, Daniel Auguin, James P. Robblee, Hailong Lu, Patricia M. Fagnant, Elena B. Krementsova, Kathleen M. Trybus, Anne Houdusse, Niels Volkmann, Dorit Hanein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Plasmodium falciparum moves by an atypical process called gliding motility which comprises of atypical myosin A (PfMyoA) and filaments of the dynamic and divergent PfActin-1 (PfAct1). Here authors present the cryo-EM structure of PfMyoA bound to fila
Externí odkaz:
https://doaj.org/article/1e9f084757d3479aa82cffe48fcd9158
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, 2022, 33 (14), pp.br28. ⟨10.1091/mbc.E22-03-0092⟩
Molecular Biology of the Cell, 2022, 33 (14), pp.br28. ⟨10.1091/mbc.E22-03-0092⟩
International audience; Matrix stiffness and dimensionality have been shown to be major determinants of cell behavior. However, a workflow for examining nanometer-scale responses of the associated molecular machinery is not available. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de62cb0c702af48ea673cccbfce57ff
https://hal.science/hal-04133460
https://hal.science/hal-04133460
Autor:
Fernando Vilela, Armel Bezault, Borja Rodriguez de Francisco, Cécile Sauvanet, Xiao-Ping Xu, Mark F. Swift, Yong Yao, Francesca M. Marrasi, Dorit Hanein, Niels Volkmann
Publikováno v:
Journal of Structural Biology
Journal of Structural Biology, 2022, 214 (4), pp.107916. ⟨10.1016/j.jsb.2022.107916⟩
Journal of Structural Biology, 2022, 214 (4), pp.107916. ⟨10.1016/j.jsb.2022.107916⟩
Nanodiscs have become a popular tool in structure determination of membrane proteins using cryogenic electron microscopy and single particle analysis. However, the structure determination of small membrane proteins remains challenging. When the embed
Autor:
FuiBoon Kai, Guanqing Ou, Richard W Tourdot, Connor Stashko, Guido Gaietta, Mark F Swift, Niels Volkmann, Alexandra F Long, Yulong Han, Hector H Huang, Jason J Northey, Andrew M Leidal, Virgile Viasnoff, David M Bryant, Wei Guo, Arun P Wiita, Ming Guo, Sophie Dumont, Dorit Hanein, Ravi Radhakrishnan, Valerie M Weaver
Publikováno v:
The EMBO Journal. 41
Patient-derived organoids and cellular spheroids recapitulate tissue physiology with remarkable fidelity. We investigated how engagement with a reconstituted basement membrane in three dimensions (3D) supports the polarized, stress resilient tissue p
Autor:
Arun P. Wiita, Bryant Dm, Margaret Guo, Guanqing Ou, FuiBoon Kai, Wei Guo, Viasnoff, Sophie Dumont, Dorit Hanein, Ravi Radhakrishnan, Yisu Han, Alexandra F. Long, Hai Huang, Andrew M. Leidal, Valerie M. Weaver, Richard W. Tourdot, Niels Volkmann, Guido Gaietta, Mark F. Swift, Jason J. Northey, Connor Stashko
Primary tissue organoids and cell spheroids recapitulate tissue physiology with remarkable fidelity. We investigated how engagement with a three dimensional laminin-rich extracellular matrix supports the polarized, stress resilient spheroid phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1e3be97f3b2adb21e8286ebf08cec3
https://doi.org/10.1101/2021.07.14.452329
https://doi.org/10.1101/2021.07.14.452329
Autor:
Niels Volkmann, Mark F. Swift, Xiao-Ping Xu, William I. Weis, Sabine Pokutta, Dorit Hanein, Miguel A. Torres
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton, and mechanical load strengthens its binding to F-actin in a direction