Is sleeping position related to asymmetry in bilateral Graves' ophthalmopathy?

Autor: Manon Bleumink, Wilmar M. Wiersinga, Lelio Baldeschi, Peerooz Saeed, Mark F. Prummel

Publikováno v: Thyroid, 18(5), 541-544. Mary Ann Liebert Inc.

BACKGROUND: In agreement with the systemic nature of Graves' disease, Graves' ophthalmopathy (GO) presents as a symmetric bilateral eye disease in the vast majority of patients. However, asymmetric involvement of both eyes is frequently observed. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b741cc2bb826cc69dbf981ede504c8
https://doi.org/10.1089/thy.2007.0302

A reduced IL2R (CD25) expression level in first and second degree female relatives of autoimmune thyroid disease patients. A sign of a poor capability to preserve tolerance?

Autor: Jan G.P. Tijssen, Wilmar M. Wiersinga, Mark F. Prummel, W.K. Lam-Tse, Thea G. A. Strieder, Hemmo A. Drexhage

Publikováno v: Autoimmunity, 39(2), 93-98. Informa Healthcare

There is room for immune markers other than TPO-Abs to identify an increased risk to develop autoimmune thyroid disease (AITD). Our aim was to test the hypothesis that activation of CD4+ T cells is such marker in relatives of AITD patients, who have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3a6341ffd5245798811594e4936daa
https://doi.org/10.1080/08916930500508092

Functional thyrotropin receptor expression in the pituitary folliculo-stellate cell line TtT/GF

Autor: Wilmar M. Wiersinga, Leon J. S. Brokken, O. Bakker, Mark F. Prummel

Publikováno v: Experimental and clinical endocrinology & diabetes, 113(1), 13-20. Thieme

Thyrotropin secretion from the anterior pituitary is regulated mainly through TRH and thyroid hormones. Recent findings of a TSH receptor (TSHR) on folliculo-stellate (FS) cells in the human anterior pituitary indicate that TSH secretion might, in ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0982d3e4aacb78bb5957f9a61f4303
https://doi.org/10.1055/s-2004-830516

Orbital irradiation for Graves' ophthalmopathy

Autor: Hendra Tan, I. M. M. J. Wakelkamp, Reinier O. Schlingemann, Frank D. Verbraak, Wilmar M. Wiersinga, Leo E.C.M. Blank, Mark F. Prummel, Peerooz Saeed

Publikováno v: Ophthalmology. 111:1557-1562

Purpose We evaluated the frequency of long-term complications of orbital irradiation (radiation-induced tumors, cataract, and retinopathy) in comparison with glucocorticoids. Design We conducted a follow-up study in a cohort of 245 Graves' ophthalmop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f4c194c56997a551ae80f323f57c011
https://doi.org/10.1016/j.ophtha.2003.12.054

A Randomized Controlled Trial of Orbital Radiotherapy Versus Sham Irradiation in Patients with Mild Graves' Ophthalmopathy

Autor: Wilmar M. Wiersinga, Leo E.C.M. Blank, Caroline B. Terwee, M. N. Gerding, Mark F. Prummel, Maarten P. Mourits, Friedo W. Dekker, Lelio Baldeschi

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 89(1), 15-20. The Endocrine Society
Prummel, M F, Terwee, C B, Gerding, M N, Baldeschi, L, Mourits, M P, Blank, L, Dekker, F W & Wiersinga, W M 2004, ' A Randomized Controlled Trial of Orbital Radiotherapy Versus Sham Irradiation in Patients with Mild Graves' Ophthalmopathy ', Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 1, pp. 15-20 . https://doi.org/10.1210/jc.2003-030809
Journal of clinical endocrinology and metabolism, 89(1), 15-20. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 89(1), 15-20. ENDOCRINE SOC

Radiotherapy is often used in Graves' ophthalmopathy, but its efficacy has been doubted. We compared its efficacy with sham irradiation in mild ophthalmopathy. In a double-blind randomized trial, 44 patients received orbital irradiation, and 44 were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc804ca6cb516b4edd47f5825b112d73
https://doi.org/10.1210/jc.2003-030809