Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Mark Ensor"'
Autor:
E. Gordon, Yasir Alsiraj, Christopher M. Waters, Charles Mark Ensor, Suresh Keshavamurthy, Robin Shoemaker, Brittany E. Dong, Jamie Sturgill, Lisa A. Cassis
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Angiotensin converting enzyme 2 (ACE2) is an enzyme that limits activity of the renin-angiotensin system (RAS) and also serves as a receptor for the SARS-CoV-2 Spike (S) protein. Binding of S protein to ACE2 causes internalization which activates loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909d1417e78696507ff97493f75da180
https://doi.org/10.1101/2021.09.14.460275
https://doi.org/10.1101/2021.09.14.460275
Autor:
Christopher M. Waters, Mark Ensor, Jamie Sturgill, Robin Shoemaker, Lisa A. Cassis, Yasir Alsiraj
Publikováno v:
Hypertension. 78
Angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 receptor and an enzyme of the renin-angiotensin system (RAS), is on the X chromosome and stimulated by estrogen. Male sex is a risk factor for SARS-CoV-2 severity. Previous investigators demonstr
Autor:
Charles Mark Ensor, Wen Su, Lisa R. Tannock, Frederique Yiannikouris, Robin Shoemaker, Lisa A. Cassis, Susan B. Gurley, Ming Gong, Sean E. Thatcher
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-12 (2019)
Biology of Sex Differences
Biology of Sex Differences
Background Obesity increases the risk for hypertension in both sexes, but the prevalence of hypertension is lower in females than in males until menopause, despite a higher prevalence of obesity in females. We previously demonstrated that angiotensin
Autor:
Nika Larian, Sean E. Thatcher, Andrew J. Morris, Arnold J. Stromberg, Lisa A. Cassis, Mark Ensor, Victoria L. English
Publikováno v:
Food Chem Toxicol
Pseudomonas aeruginosa, a leading cause of sepsis, produces pyocyanin, a blue-pigmented virulence factor. Sepsis is associated with cachexia, but mechanisms are unknown and conventional nutrition approaches are not effective treatments. Pyocyanin has
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
Combined neprilysin (NEP) inhibition (sacubitril) and angiotensin type 1 receptor (AT1R) antagonism (valsartan) is used in the treatment of congestive heart failure and is gaining interest for other angiotensin II (AngII)-related cardiovascular disea
Autor:
Carolina Dalmasso, Charles Mark Ensor, Frederique Yiannikouris, Analia S. Loria, Jorge F. Giani, Lisa A. Cassis, Jacqueline R. Leachman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We have previously reported that female mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show exacerbated diet‐induced obesity associated with hypertension. The goal of this study was to test wh
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783319937007
ICCS (2)
ICCS (2)
Ellagic acid (EA) is a polyphenolic compound with antiviral activity against chikungunya, a rapidly spreading new tropical disease transmitted to humans by mosquitoes and now affecting millions worldwide. The most common symptoms of chikungunya virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2b400ebd2d5c13f88e959ceeb3a9874
https://doi.org/10.1007/978-3-319-93701-4_61
https://doi.org/10.1007/978-3-319-93701-4_61
Publikováno v:
Webmedcentral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9b8aeeaa05fdbdc737c2b291f1b9189e
https://europepmc.org/articles/PMC9451009/
https://europepmc.org/articles/PMC9451009/
Publikováno v:
Journal of endocrinology, diabetesobesity. 3(1)
The primary objectives of this study were to evaluate the treatment effect of D-tagatose on glycemic control, determined by a statistically significant decrease in hemoglobin A1c (HbA1c), and safety profile of D-tagatose compared to placebo. The seco
Publikováno v:
Analytical Biochemistry. 421:172-180
Protein engineering has generated versatile methods and technologies that have been instrumental in advancements in the fields of sensing, therapeutics and diagnostics. Herein, we demonstrate the employment of rational design to engineer a unique bio