Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mark Eller"'
Autor:
Katie Zomorodi, Paola Tocchetti, Thomas C. Marbury, Elena Tudone, Jean Francois Marier, Mark Eller
Publikováno v:
Drug Design, Development and Therapy
Paola Tocchetti,1 Elena Tudone,2 Jean-Francois Marier,3 Thomas C Marbury,4 Katie Zomorodi,5 Mark Eller6 1Gentium, 2Clinical Operations, Gentium, Villa Guardia, Como, Italy; 3Reporting and Analysis Services, Pharsight, a Certara Company, Montreal, Que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77287cb3eb82e1533ebe4cedfe1cecc
https://doi.org/10.2147/dddt.s112181
https://doi.org/10.2147/dddt.s112181
Publikováno v:
Sleep. 37:439-444
Objective To evaluate the mortality rate in patients with narcolepsy. Design Data were derived from a large database representative of the US population, which contains anonymized patient-linked longitudinal claims for 173 million individuals. Settin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa9379b54c00bda4b3814321d316452
https://doi.org/10.5665/sleep.3470
https://doi.org/10.5665/sleep.3470
Publikováno v:
European Journal of Pharmacology. 602:316-320
JZP-4 is a novel with anticonvulsant, antidepressant and antimania effects in preclinical models. It has some structural similarity to the sodium channel blocker, lamotrigine, but it has both potent sodium and calcium channel blocking activity. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c51c9193f46da6c5d9c5a33c07e2b9
https://doi.org/10.1016/j.ejphar.2008.11.013
https://doi.org/10.1016/j.ejphar.2008.11.013
Autor:
James P. Stables, Mark M. Foreman, H. Steve White, Sharon C Stratton, Mark Eller, Karen S. Wilcox, Taleen Hanania
Publikováno v:
Pharmacology Biochemistry and Behavior. 89:523-534
JZP-4 is a potent calcium and sodium channel blocker, which is currently being evaluated in patients as an anticonvulsant and mood stabilizer. In the current studies, JZP-4 was evaluated in a variety of animal models for anticonvulsant, antimania and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca894052e7da6f93520da3ecec1d05aa
https://doi.org/10.1016/j.pbb.2008.02.007
https://doi.org/10.1016/j.pbb.2008.02.007
Publikováno v:
Blood. 128:1631-1631
Introduction: Asparaginase Erwinia chrysanthemi (Erwinia), an asparagine-specific enzyme indicated as a component of a multiagent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia (ALL) who have developed hypers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d615f6a068f7cc07f93dbba6ea9fb1f1
https://doi.org/10.1182/blood.v128.22.1631.1631
https://doi.org/10.1182/blood.v128.22.1631.1631
Publikováno v:
The Journal of Cell Biology
Nerve growth factor (NGF) is critical to the development and maintenance of the peripheral nervous system, but its possible roles in other organ systems are less well characterized. We have recently shown that human epidermal melanocytes, pigment cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121fd447408e2b92176e6a3d76ed839d
https://doi.org/10.1083/jcb.115.3.821
https://doi.org/10.1083/jcb.115.3.821
Publikováno v:
Journal of clinical pharmacology. 45(5)
The primary objectives of this study were to characterize the absolute bioavailability of azacitidine after subcutaneous (SC) administration and to compare the single-dose pharmacokinetics of azacitidine following SC and intravenous (IV) administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d10b189ba97c50be5c7f8cb6b1255e6
https://pubmed.ncbi.nlm.nih.gov/15831784
https://pubmed.ncbi.nlm.nih.gov/15831784
Autor:
Mark Eller
Publikováno v:
Pharmacokinetics in Drug Discovery and Development ISBN: 9781566769730
Pharmacokinetics in Drug Discovery and Development
Pharmacokinetics in Drug Discovery and Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28575cfc814b23f26fa2ae619f20e3b6
https://doi.org/10.1201/9781420010084.ch4
https://doi.org/10.1201/9781420010084.ch4
Publikováno v:
Clinical pharmacology and therapeutics. 58(3)
A double-blind placebo-controlled study was conducted in healthy men to determine the effect of coadministration of azithromycin on the pharmacodynamics and pharmacokinetics of terfenadine. Administration of 500 mg azithromycin for 1 day and 250 mg o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0ccb720b749db54d6a69e4dfbab4c9
https://pubmed.ncbi.nlm.nih.gov/7554704
https://pubmed.ncbi.nlm.nih.gov/7554704
Publikováno v:
Experimental cell research. 198(2)
Retinoic acid (RA) is known to have a profound effect on the growth and differentiation of human epidermal cells in vivo and in vitro. One of the proteins thought to be involved in mediating the action of RA is the cellular retinoic acid-binding prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0241548d568986f68a41534eb4a50753
https://pubmed.ncbi.nlm.nih.gov/1309505
https://pubmed.ncbi.nlm.nih.gov/1309505