Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mark Eiseman"'
Autor:
Jun Sun, Dong Yeon Shin, Mark Eiseman, Alisha R. Yallowitz, Na Li, Sarfaraz Lalani, Zan Li, Michelle Cung, Seoyeon Bok, Shawon Debnath, Sofia Jenia Marquez, Tommy E. White, Abdul G. Khan, Ivo C. Lorenz, Jae-Hyuck Shim, Francis S. Lee, Ren Xu, Matthew B. Greenblatt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Hedgehog signaling is essential for bone formation. Here, the authors show that the transmembrane protein SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts, suggesting it may be a potential therapeutic target to enhance bone format
Externí odkaz:
https://doaj.org/article/336539fea16c45a5b002c405f1af2ce5
Autor:
Seoyeon Bok, Dong Yeon Shin, Alisha R. Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu, Na Li, Jun Sun, Alfred L. Williams, John E. Scott, Bing Su, Jae-Hyuck Shim, Matthew B. Greenblatt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Neurofibromatosis type I (NF1) is characterized by prominent skeletal abnormalities mediated in part by aberrant ERK pathway activation due to NF1 loss-of-function. Here, the authors report the MEKK2 is a key mediator of this aberrant ERK activation
Externí odkaz:
https://doaj.org/article/1bdc5e8883dd407b82aab19c4cfb975b
Autor:
Mark Eiseman, Matthew B. Greenblatt, Jae-Hyuck Shim, Jun Sun, Alisha R. Yallowitz, Dong Yeon Shin, Na Li, Michelle Cung, Bing Su, Seoyeon Bok, Ren Xu, Alfred L. Williams, John E. Scott
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Neurofibromatosis type I (NF1) is characterized by prominent skeletal manifestations caused by NF1 loss. While inhibitors of the ERK activating kinases MEK1/2 are promising as a means to treat NF1, the broad blockade of the ERK pathway produced by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0f24f190ae8316acceb682d204a810
http://europepmc.org/articles/PMC7658220
http://europepmc.org/articles/PMC7658220
Autor:
Sarfaraz Lalani, Dong Yeon Shin, Seoyeon Bok, Michelle Cung, Abdul G. Khan, Zan Li, Ren Xu, Matthew B. Greenblatt, Jae-Hyuck Shim, Jun Sun, Alisha R. Yallowitz, Na Li, Sofia Jenia Marquez, Ivo C. Lorenz, Tommy E. White, Shawon Debnath, Francis S. Lee, Mark Eiseman
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Hedgehog signaling is essential for bone formation, including functioning as a means for the growth plate to drive skeletal mineralization. However, the mechanisms regulating hedgehog signaling specifically in bone-forming osteoblasts are largely unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162afb6aa92d53b58d67a35b4a2cf905
https://pubmed.ncbi.nlm.nih.gov/34326333
https://pubmed.ncbi.nlm.nih.gov/34326333
Autor:
Mark Eiseman, Jung-Min Kim, Sarfaraz Lalani, Jae-Hyuck Shim, Matthew B. Greenblatt, Yeon-Suk Yang, Yifang Liu, Dong Yeon Shin, Ren Xu, Chao Zhang, Na Li, Roger J. Davis
Publikováno v:
Journal of Bone and Mineral Research. 32:1811-1815
The c-Jun N-terminal kinases (JNKs) are ancient and evolutionarily conserved regulators of proliferation, differentiation, and cell death responses. Currently, in vitro studies offer conflicting data about whether the JNK pathway augments or represse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b45f8dafa6eace35c7f86770067d6f
https://doi.org/10.1002/jbmr.3184
https://doi.org/10.1002/jbmr.3184
Autor:
Alisha R. Yallowitz, John H. Healey, Ren Xu, Dan A. Landau, Mathias P.G. Bostrom, Jason McCormick, Sarfaraz Lalani, Shawon Debnath, Tuo Zhang, Mark Eiseman, Matthew B. Greenblatt, Meera Hameed, Yifang Liu, Yeon Suk Yang, Jae-Hyuck Shim, Na Li
Publikováno v:
Nature
Bone consists of separate inner endosteal and outer periosteal compartments, each with distinct contributions to bone physiology and each maintaining separate pools of cells owing to physical separation by the bone cortex. The skeletal stem cell that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6761be76953bbec83d7af0ec2e396ed
https://pubmed.ncbi.nlm.nih.gov/30250253
https://pubmed.ncbi.nlm.nih.gov/30250253
Publikováno v:
Geospatial Tools for Urban Water Resources ISBN: 9789400747333
This chapter provides a comprehensive and chronological review of the procedures that were used to identify suitable sites for wetland and stream restoration in the Swan Creek and Tenmile Creek/Ottawa River watersheds within northwest Ohio. It includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e018c334723efc69fc598271aab8e8e
https://doi.org/10.1007/978-94-007-4734-0_7
https://doi.org/10.1007/978-94-007-4734-0_7
