Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark Edward Carl, Dockrell"'
Autor:
Sarah Yates, Andrew N. Chapman, Bruce M. Hendry, Mark Edward Carl Dockrell, Paul Roderick, Robert G. Price, Mysore K. Phanish
Publikováno v:
Kidney International Reports
Introduction Albuminuric and nonalbuminuric pathways contribute to diabetic kidney disease. Proximal tubule and inflammation play important roles in these processes. Urinary biomarker(s) to detect early kidney damage and predict progression are neede
Publikováno v:
American Journal of Biomedical Science & Research. 9:8-10
Publikováno v:
Bioscience Reports
Background: In the kidney glucose is freely filtered by the glomerulus and, mainly, reabsorbed by sodium glucose cotransporter 2 (SGLT2) expressed in the early proximal tubule. Human proximal tubule epithelial cells (PTECs) undergo pathological and f
Publikováno v:
Cellular and Molecular Biology. 64:127-135
Alternative splicing is an important gene regulation process to distribute proteins in health and diseases. Extra Domain A+ Fibronectin (EDA+Fn) is an alternatively spliced form of fibronectin (Fn) protein, present in the extra cellular matrix (ECM)
Publikováno v:
Cellular and Molecular Biology. 64:45-52
The interactions of the extracellular matrix (ECM) proteins with cells strongly regulate cell behaviour. The glomerular basement membrane (GBM) is a dynamic structure made up of protein secreted by endothelial cells and podocyte. These proteins could
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 64(3)
Alternative splicing is a fundamental phenomenon to build protein diversity in health and diseases. Extra Domain A+ Fibronectin (EDA+Fn) is an alternatively spliced form of fibronectin protein present in the extra cellular matrix (ECM) in renal fibro
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 64(3)
Growth factors like TGFβ and CTGF (CCN2) plays a vital role in various cellular functions. TGFβ and CTGF are overexpressed in renal fibrosis. CTGF act as profibrotic stimuli to TGFβ. CCN3 is a member of CCN family which also comprises CCN1 (
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 64(5)
Alternative splicing is an important gene regulation process to distribute proteins in health and diseases. Extra Domain A+ Fibronectin (EDA+Fn) is an alternatively spliced form of fibronectin (Fn) protein, present in the extra cellular matrix (ECM)
Publikováno v:
Journal of Applied Microbiology. 108:1828-1838
Aims: To evaluate a new range of chromogenic substrates for the detection of β-galactosidase activity in coliforms and to compare their performance in agar media and broths. Methods and Results: Sixteen novel galactoside substrates were prepared and
Autor:
Mysore Keshavmurthy, Phanish, Felicia, Heidebrecht, Mohammad E, Nabi, Nileshkumar, Shah, Ioana, Niculescu-Duvaz, Mark Edward Carl, Dockrell
Publikováno v:
Journal of cellular physiology. 230(2)
The EDA+ splice variant of fibronectin (Fn) is an early and important component of the extracellular matrix in renal fibrosis. In this work, we investigate cellular mechanisms of EDA+Fn production in human primary proximal tubule epithelial cells (PT