Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Mark E. Smulson"'
Autor:
Cynthia M. Simbulan-Rosenthal, Dean S. Rosenthal, RuiBai Luo, Raed Samara, Mira Jung, Anatoly Dritschilo, Alexander Spoonde, Mark E. Smulson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 3, Pp 179-188 (2001)
The tumor-suppresser p53 undergoes extensive poly(ADP-ribosyl)ation early during apoptosis in human osteosarcoma cells, and degradation of poly(ADP-ribose) (PAR) attached to p53 coincides with poly(ADP-ribose)polymerase-1, (PARP-1) cleavage, and expr
Externí odkaz:
https://doaj.org/article/74a355d957e94f919115adbe1be7517a
Autor:
Mark E. Smulson, Najma Malik
Publikováno v:
Chromosomal Nonhistone Proteins ISBN: 9781351076074
Chromosomal Nonhistone Proteins ISBN: 9781351070669
Chromosomal Nonhistone Proteins
Chromosomal Nonhistone Proteins ISBN: 9781351070669
Chromosomal Nonhistone Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac550a96e6fc51d1157f7634f8238d3a
https://doi.org/10.1201/9781351076074-6
https://doi.org/10.1201/9781351076074-6
Autor:
Mohamed A. Ghonim, Ali H. El-Bahrawy, Jihang Ju, Jianhua Zhang, Ming Xu, Amarjit S. Naura, Yasuhiro Suzuki, Ramadan A.M. Hemeida, A. Hamid Boulares, Youssef Errami, Mark E. Smulson, Moselhy S Mansy, Hassan Brim, Hogyoung Kim
Publikováno v:
Journal of Biological Chemistry. 288:3460-3468
Caspase-activated DNase (CAD) is the most favorable candidate for chromatin degradation during apoptosis. Ca2+-dependent endonucleases are equally important in internucleosomal DNA fragmentation (INDF), including the PARP-1-regulated DNAS1L3. Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdf4012c164cdeef070aafee7eabac4
https://doi.org/10.1074/jbc.m112.423061
https://doi.org/10.1074/jbc.m112.423061
Autor:
A. Hamid Boulares, Jihang Ju, Amarjit S. Naura, Charles Giardina, Asim B. Abdel-Mageed, Mark E. Smulson, Youssef Errami, Mourad Zerfaoui, Amer A. Beg, Hogyoung Kim, Jong G. Kim, Zakaria Y. Abd Elmageed
Publikováno v:
Journal of Biological Chemistry. 285:41152-41160
The DNA binding activity of NF-κB is critical for VCAM-1 expression during inflammation. DNA-dependent protein kinase (DNA-PK) is thought to be involved in NF-κB activation. Here we show that DNA-PK is required for VCAM-1 expression in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081a11fc3b751e3bd49a56f99f1b1fd6
https://doi.org/10.1074/jbc.m110.158352
https://doi.org/10.1074/jbc.m110.158352
Publikováno v:
The Prostate. 70:1211-1221
BACKGROUND Phenoxodiol, a synthetic analog of Genistein, is being assessed in several clinical studies against a range of cancer types and was shown to have a good efficacy and safety profile. In this study we tested the effects of Phenoxodiol agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78135660fe4d546e57fb92dc628420d1
https://doi.org/10.1002/pros.21156
https://doi.org/10.1002/pros.21156
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 35:479-487
Lung epithelial cells are critical in the regulation of airway inflammation in response to environmental pollutants. Altered activation of NF-kappaB is associated with expression of several proinflammatory factors in respiratory epithelial cells in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c782fa099519c6450b6313d51f34c676
https://doi.org/10.1165/rcmb.2006-0059oc
https://doi.org/10.1165/rcmb.2006-0059oc
Publikováno v:
European Journal of Biochemistry. 113:15-25
Poly(ADP-ribose) [poly(ADP-Rib)] polymerase of HeLa nucleosomes has been shown in vitro, to catalyze the synthesis of a complex of histone H1 containing 2 H1 histones and 15–16 units of oligo(ADP-Rib). The synthesis of the H1 complex in vitro was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb139c174c7790e2c0599d0fb9073ee7
https://doi.org/10.1111/j.1432-1033.1980.tb06133.x
https://doi.org/10.1111/j.1432-1033.1980.tb06133.x
Publikováno v:
The American Journal of Human Genetics. 76(3):478-492
Alleles at NACP-Rep1, the polymorphic microsatellite repeat located approximately 10 kb upstream of the alpha -synuclein gene (SNCA), are associated, in some reports, with differing risks of sporadic Parkinson disease (PD). We showed previously that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f2a8f9769dbb6285880f45e8b98b22
Autor:
Mark L. Witten, Theresa Carr, Mira Jung, Mohammad Valikhani, Juanita Hyde, Luis A. Espinoza, Mark E. Smulson, María J. Cossio
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 32:192-200
Many military personnel are at risk of lung damage or systemic toxicity as a result of exposure to the jet fuel JP-8. We have now used microarray analysis to characterize changes in the gene expression profile of lung tissue induced by exposure of ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49c3f4a64e4c955ddf58463e5ac996a
https://doi.org/10.1165/rcmb.2004-0171oc
https://doi.org/10.1165/rcmb.2004-0171oc
Publikováno v:
Cytometry Part A. :21-27
Background Poly(ADP-ribose)polymerase-1 (PARP-1) binds to single and double-stranded breaks in DNA, but less well known is its affinity for undamaged DNA. Previously, we have shown that PARP-1 also binds to the hairpin structures in DNA models. The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699da4091654a1f2776ce27a30b0da7f
https://doi.org/10.1002/cyto.a.20187
https://doi.org/10.1002/cyto.a.20187