Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mark E. Schneider"'
Autor:
Laura N. Puentes, Zsofia Lengyel-Zhand, Ji Youn Lee, Chia-Ju Hsieh, Mark E. Schneider, Kimberly J. Edwards, Kelvin C. Luk, Virginia M.-Y. Lee, John Q. Trojanowski, Robert H. Mach
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Poly (ADP-ribose) (PAR) is a negatively charged polymer that is biosynthesized by Poly (ADP-ribose) Polymerase-1 (PARP-1) and regulates various cellular processes. Alpha-synuclein (αSyn) is an intrinsically disordered protein (IDP) that has been dir
Externí odkaz:
https://doaj.org/article/2deab56410f34193b971dfcf9ccf783e
Autor:
Chia-Ju Hsieh, Zsofia Lengyel-Zhand, Virginia M.-Y. Lee, Kimberly J. Edwards, Laura N. Puentes, Kelvin C. Luk, Mark E. Schneider, John Q. Trojanowski, Robert H. Mach, Ji Youn Lee
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
Poly (ADP-ribose) (PAR) is a negatively charged polymer that is biosynthesized by Poly (ADP-ribose) Polymerase-1 (PARP-1) and regulates various cellular processes. Alpha-synuclein (αSyn) is an intrinsically disordered protein (IDP) that has been dir
Autor:
Robert H. Mach, Ji Youn Lee, Chia-Ju Hsieh, Mark E. Schneider, Kimberly J. Edwards, John Q. Trojanowski, Laura N. Puentes, Zsofia Lengyel-Zhand, Kelvin C. Luk, Virginia M.-Y. Lee
BackgroundPoly (ADP-ribose) (PAR) is a negatively charged polymer that is biosynthesized by Poly (ADP-ribose) Polymerase-1 (PARP-1) and regulates various cellular processes. Alpha-synuclein (αSyn) is an intrinsically disordered protein (IDP) that ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40756ece61678a83ac412bed7787b1ce
Autor:
Mehran Makvandi, Linda X. Jin, Kuiying Xu, Mark E. Schneider, Aladdin Riad, Chenbo Zeng, Chi-Chang Weng, William G. Hawkins, Laura N. Puentes, Robert H. Mach
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 5, Iss 1, Pp 1-12 (2019)
Cell Death Discovery, Vol 5, Iss 1, Pp 1-12 (2019)
Sigma-2 receptors have been implicated in both tumor proliferation and neurodegenerative diseases. Recently the sigma-2 receptor was identified as transmembrane protein 97 (TMEM97). Progesterone receptor membrane component 1 (PGRMC1) was also recentl
Autor:
Gavin P. Riordan, Bechara Kachar, Caroline Davies, Agnieszka K. Rzadzinska, Mark E. Schneider
Publikováno v:
The Journal of Cell Biology
We have previously shown that the seemingly static paracrystalline actin core of hair cell stereocilia undergoes continuous turnover. Here, we used the same approach of transfecting hair cells with actin–green fluorescent protein (GFP) and espin-GF
Publikováno v:
Naval Engineers Journal. 104:166-177
Several methods for evaluating thermal performance of ablative materials under simulated solid rocket exhaust plumes are presented in this paper. A small-scale supersonic rocket motor facility capable of delivering more than 700 Btu/s-ft2 (7,947 kW/m
Autor:
Bechara Kachar, F L Erickson, Beth Burnside, Andréa C. Dosé, Mark E. Schneider, Weise Chang, Felipe T. Salles
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(40)
Class III myosins are motor proteins that contain an N-terminal kinase domain and a C-terminal actin-binding domain. We show that myosin IIIa, which has been implicated in nonsyndromic progressive hearing loss, is localized at stereocilia tips. Myosi
Autor:
Karen Lipkow, M'hamed Grati, Emanuel E. Strehler, Robert J. Wenthold, Mark E. Schneider, Bechara Kachar
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(23)
We studied the spatial distribution, mobility, and trafficking of plasma membrane Ca2+ATPase-2 (PMCA2), a protein enriched in the hair cell apical membrane and essential for hair cell function. Using immunofluorescence, we determined that PMCA2 is en
Publikováno v:
Current opinion in cell biology. 17(1)
Stereocilia, the mechanosensitive protrusions in hair cells, are organized into rows of graded heights forming precisely uniform staircase patterns. The actin turnover process in stereocilia follows a treadmill model in which the rate of treadmilling
Publikováno v:
Nature. 418:837-838
Stereocilia, also known as hair bundles, are mechanosensitive organelles of the sensory hair cells of the inner ear that can detect displacements on a nanometre scale and are supported by a rigid, dense core of actin filaments. Here we show that thes