Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark E. S. Bailey"'
Autor:
Joey Ward, Laura M. Lyall, Breda Cullen, Rona J. Strawbridge, Xingxing Zhu, Ioana Stanciu, Alisha Aman, Claire L. Niedzwiedz, Jana Anderson, Mark E. S. Bailey, Donald M. Lyall, Jill P. Pell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Happiness is a fundamental human affective trait, but its biological basis is not well understood. Using a novel approach, we construct LDpred-inf polygenic scores of a general happiness measure in 2 cohorts: the Adolescent Brain Cognitive D
Externí odkaz:
https://doaj.org/article/80fe9bf8ebab4344ac6435ca01993e32
Autor:
Rona J. Strawbridge, Keira J. A. Johnston, Mark E. S. Bailey, Damiano Baldassarre, Breda Cullen, Per Eriksson, Ulf deFaire, Amy Ferguson, Bruna Gigante, Philippe Giral, Nicholas Graham, Anders Hamsten, Steve E. Humphries, Sudhir Kurl, Donald M. Lyall, Laura M. Lyall, Jill P. Pell, Matteo Pirro, Kai Savonen, Andries J. Smit, Elena Tremoli, Tomi-Pekka Tomainen, Fabrizio Veglia, Joey Ward, Bengt Sennblad, Daniel J. Smith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Understanding why individuals with severe mental illness (Schizophrenia, Bipolar Disorder and Major Depressive Disorder) have increased risk of cardiometabolic disease (including obesity, type 2 diabetes and cardiovascular disease), and iden
Externí odkaz:
https://doaj.org/article/7e59d46ec2fd4250ae99b8ac5242f619
Autor:
Niklas Mähler, Bastian Schiffthaler, Kathryn M. Robinson, Barbara K. Terebieniec, Matej Vučak, Chanaka Mannapperuma, Mark E. S. Bailey, Stefan Jansson, Torgeir R. Hvidsten, Nathaniel R. Street
Publikováno v:
Ecology and Evolution, Vol 10, Iss 21, Pp 11922-11940 (2020)
Abstract Leaf shape is a defining feature of how we recognize and classify plant species. Although there is extensive variation in leaf shape within many species, few studies have disentangled the underlying genetic architecture. We characterized the
Externí odkaz:
https://doaj.org/article/90be3732777d4d81bdb0d07e7c0fbccf
Autor:
Breda Cullen, Marc J. Gameroff, Joey Ward, Mark E. S. Bailey, Donald M. Lyall, Laura M. Lyall, Niamh MacSweeney, Eleanor Murphy, Natasha Sangha, Xueyi Shen, Rona J. Strawbridge, Milenna T. van Dijk, Xingxing Zhu, Daniel J. Smith, Ardesheer Talati, Heather C. Whalley, Jonathan Cavanagh, Myrna M. Weissman
Publikováno v:
Cullen, B, Gameroff, M J, Ward, J, Bailey, M E S, Lyall, D M, Lyall, L M, MacSweeney, N, Murphy, E, Sangha, N, Shen, X, Strawbridge, R J, Van Dijk, M, Zhu, X, Smith, D, Talati, A, Whalley, H, Cavanagh, J & Weissman, M M 2023, ' Cognitive Function in People With Familial Risk of Depression ', JAMA Psychiatry . https://doi.org/10.1001/jamapsychiatry.2023.0716
ImportanceCognitive impairment in depression is poorly understood. Family history of depression is a potentially useful risk marker for cognitive impairment, facilitating early identification and targeted intervention in those at highest risk, even i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff915cf1dbacd92833b9c54209b923f
https://www.pure.ed.ac.uk/ws/files/344790873/Cullen_et_al_JAMA_Psychiatry_in_press..pdf
https://www.pure.ed.ac.uk/ws/files/344790873/Cullen_et_al_JAMA_Psychiatry_in_press..pdf
Autor:
Keira J A Johnston, Mark J Adams, Barbara I Nicholl, Joey Ward, Rona J Strawbridge, Amy Ferguson, Andrew M McIntosh, Mark E S Bailey, Daniel J Smith
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008164 (2019)
Chronic pain is highly prevalent worldwide and represents a significant socioeconomic and public health burden. Several aspects of chronic pain, for example back pain and a severity-related phenotype 'chronic pain grade', have been shown previously t
Externí odkaz:
https://doaj.org/article/6e0d01fadc5844099ff9cabe52d03cc2
Autor:
Francesco Gianfagna, Claudio Grippi, Wolfgang Ahrens, Mark E S Bailey, Claudia Börnhorst, Stefan De Henauw, Ronja Foraita, Anna C Koni, Vittorio Krogh, Staffan Mårild, Dénes Molnár, Luis Moreno, Yannis Pitsiladis, Paola Russo, Alfonso Siani, Michael Tornaritis, Toomas Veidebaum, Licia Iacoviello
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172698 (2017)
BACKGROUND AND AIMS:Neuromedin U (NMU) is a hypothalamic neuropeptide with important roles in several metabolic processes, recently suggested as potential therapeutic target for obesity. We analysed the associations between NMU gene variants and hapl
Externí odkaz:
https://doaj.org/article/e4dfc2abbb824d4789461ddab1a7e900
Autor:
Joey Ward, Laura Lyall, Breda Cullen, Rona J. Strawbridge, Xingxing Zhu, Ioana Stanciu, Alisha Aman, Claire L. Niedzwiedz, Jana Anderson, Mark E. S. Bailey, Donald M. Lyall, Jill Pell
We present a genome-wide association study of a general happiness measure in 118,851 participants from the UK Biobank. Using BOLT-LMM, we identify 3 significant loci with a heritability estimate of 0.8%. Linkage disequilibrium score regression was pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f5c07fa845ba24316ac39df5d29c85f
https://doi.org/10.1101/2022.04.05.487098
https://doi.org/10.1101/2022.04.05.487098
Autor:
Ralph D Hector, Owen Dando, Nicoletta Landsberger, Charlotte Kilstrup-Nielsen, Peter C Kind, Mark E S Bailey, Stuart R Cobb
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157758 (2016)
Mutations in the X-linked Cyclin-Dependent Kinase-Like 5 gene (CDKL5) cause early onset infantile spasms and subsequent severe developmental delay in affected children. Deleterious mutations have been reported to occur throughout the CDKL5 coding reg
Externí odkaz:
https://doaj.org/article/9a584d0583cf4017904a95080225be63
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112889 (2014)
Rett syndrome (RTT) is a genetic disorder characterized by a range of features including cognitive impairment, gait abnormalities and a reduction in purposeful hand skills. Mice harbouring knockout mutations in the Mecp2 gene display many RTT-like ch
Externí odkaz:
https://doaj.org/article/fbd81503313d477bb13f07d3700029f2
Autor:
Carlos A, Celis-Morales, Donald M, Lyall, Fanny, Petermann, Jana, Anderson, Joey, Ward, Stamatina, Iliodromiti, Daniel F, Mackay, Paul, Welsh, Mark E S, Bailey, Jill, Pell, Naveed, Sattar, Jason M R, Gill, Stuart R, Gray
Publikováno v:
International journal of obesity (2005). 43(8)
To investigate whether the association between a genetic profile risk score for obesity (GPRS-obesity) (based on 93 SNPs) and body mass index (BMI) was modified by physical activity (PA), cardiorespiratory fitness, commuting mode, walking pace and se