Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mark E. Rerek"'
Publikováno v:
The Journal of Physical Chemistry B. 110:2378-2386
The major barrier to permeability in skin resides in the outermost layer of the epidermis, the stratum corneum (SC). The major SC lipid components are ceramides, free fatty acids, and cholesterol. Ternary mixtures containing these constituents are wi
Publikováno v:
Chemistry and Physics of Lipids. 134:51-58
IR spectroscopic studies are reported for N-stearyl-D-erythro-phytosphingosine (Cer NP) and N-stearyl-2-hydroxy-D-erythro-phytosphingosine (Cer AP) in a hydrated model of the skin lipid barrier comprised of equimolar mixtures of each ceramide with ch
Publikováno v:
Journal of Investigative Dermatology. 124(3):622-632
The feasibility of monitoring the permeation of chain perdeuterated 1,2-dipalmitoylphosphatidylcholine (DPPC-d62) and 1-palmitoyl-d31, 2-oleoylphosphatidylcholine (P-d31OPC) vesicles into pigskin using infrared (IR) microscopic imaging and confocal R
Autor:
Patrick Garidel, Dina Van Wyck, Hui-Chen Chen, David J. Moore, Berislav Marković, Mark E. Rerek, and Richard Mendelsohn
Publikováno v:
The Journal of Physical Chemistry B. 105:9355-9362
IR spectroscopic studies are reported for the phytosphingosine class of ceramides and are compared with two analogous sphingosine ceramides. The phytosphingosine class of molecules, not previously widely investigated by physical techniques, constitut
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1468(1-2):293-303
Ceramides provide a major component of the barrier function of skin. An understanding of barrier organization requires a detailed characterization of ceramide phase behavior and molecular interactions. Toward this end, Fourier transform infrared (FTI
Autor:
Mark E. Rerek, David J. Moore
Publikováno v:
Acta Dermato-Venereologica. 80:16-22
In order to gain some insight into the molecular organization of lipids in the skin barrier we used Fourier transform infrared (FTIR) spectroscopy to investigate models of the stratum corneum (SC) containing deuterated hexadecanoic acid, cholesterol,
Publikováno v:
The Journal of Physical Chemistry B. 104:2159-2165
One, two, and three component lipid models of the stratum corneum (SC) consisting of non hydroxy fatty acid (NFA) ceramide, cholesterol, and perdeuterated palmitic acid have been investigated as monolayers at the air/water interface. Infrared reflect
Publikováno v:
Physical Chemistry Chemical Physics. 2:4651-4657
The highly ordered ceramide-containing phases that constitute the barrier to permeability in the stratum corneum are well-suited for examination by IR spectroscopy, and the chain vibrations have been widely investigated in this context. The current s
Publikováno v:
International Journal of Cosmetic Science. 21:353-368
We utilized Fourier transform infrared (FTIR) spectroscopy to investigate headgroup and chain interactions in model SC lipid barriers containing equimolar amounts of deuterated hexadecanoic acid, cholesterol, and ceramide 2 (non-hydroxy sphingosine)
Publikováno v:
The Journal of Physical Chemistry B. 101:8933-8940
Ceramides, the major lipid component of the stratum corneum (SC), provide many of its unique physical properties. Surprisingly, only a few biophysical studies of hydrated ceramides have been report...