Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mark E. Pulse"'
Autor:
Johan A. Kers, Robert E. Sharp, Anthony W. Defusco, Jae H. Park, Jin Xu, Mark E. Pulse, William J. Weiss, Martin Handfield
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Lantibiotics offer an untapped pipeline for the development of novel antibiotics to treat serious Gram-positive (+) infections including Clostridium difficile. Mutacin 1140 (MU1140) is a lantibiotic produced by Streptococcus mutans and acts via a nov
Externí odkaz:
https://doaj.org/article/b817fd7f62a14cda95a6d257a5f10e9a
Autor:
Cailin E. Deal, Angelene F. Richards, Tracy Yeung, Max J. Maron, Ziqiu Wang, Yen-Ting Lai, Brian R. Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J. Hsiao, Ivana L. Rajlic, Hillary Koch, Michael Kleyman, Mark E. Pulse, William J. Weiss, Jennifer E. Doering, Samantha K. Lindberg, Nicholas J. Mantis, Andrea Carfi, Obadiah J. Plante
Monoclonal antibody (mAb) therapy is a promising infectious disease intervention strategy but is limited to IgG1 isotypes that have restricted access to mucosal sites. IgA is well-established as the predominant antibody isotype in mucosal secretions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ed2510c7cb21c1a99b7d4f587b5f75
https://doi.org/10.1101/2023.01.03.521487
https://doi.org/10.1101/2023.01.03.521487
Autor:
Cailin Deal, Angelene F. Richards, Tracy Yeung, Max J. Maron, Ziqiu Wang, Yen-Ting Lai, Brian R. Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J. Hsiao, Ivana L. Rajlic, Hillary Koch, Michael Kleyman, Mark E. Pulse, William J. Weiss, Jennifer E. Doering, Samantha K. Lindberg, Nicholas Mantis, Andrea Carfi, Obadiah J. Plante
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42cf464e45ecec222f7250343520feeb
https://doi.org/10.2139/ssrn.4423986
https://doi.org/10.2139/ssrn.4423986
Autor:
Cassandra L, Chatwin, Jodie C, Hamrick, Robert E L, Trout, Cullen L, Myers, Susan M, Cusick, William J, Weiss, Mark E, Pulse, Luigi, Xerri, Christopher J, Burns, Gregory, Moeck, Denis M, Daigle, Kaitlyn, John, Tsuyoshi, Uehara, Daniel C, Pevear
Publikováno v:
Antimicrobial Agents and Chemotherapy
There is an urgent need for oral agents to combat resistant Gram-negative pathogens. Here, we describe the characterization of VNRX-5236, a broad-spectrum boronic acid β-lactamase inhibitor (BLI), and its orally bioavailable etzadroxil prodrug, VNRX
Autor:
Johan A Kers, Anthony W DeFusco, Jae H Park, Jin Xu, Mark E Pulse, William J Weiss, Martin Handfield
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197467 (2018)
Lantibiotics continue to offer an untapped pipeline for the development of novel antibiotics. We report here the discovery of a novel lantibiotic for the treatment of C. difficile infection (CDI). The leads were selected from a library of over 300 mu
Externí odkaz:
https://doaj.org/article/8576e0e2154a45a69a25cf4db2f4e489