Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mark E. Ireland"'
Publikováno v:
Journal of Cellular Physiology. 186:288-297
TGFα is hypothesized to be an endogenous regulator of lens fiber terminal differentiation. With immunofluorescence, TGFα was localized to differentiating cells in the lens epithelium and superficial fiber cell mass of the adult chicken. A similar p
Autor:
Harry Maisel, Michael Kasper, Ailian Liu, Paul S. Wallace, Mark E. Ireland, Michael S. Poosch, Roy A. Quinlan, Jochen Graw, Alan R. Prescott, Aileen Sandilands, Dennis J. Goebel, A.M. Hutcheson
Publikováno v:
The Anatomical Record. 258:25-33
The early embryonic development and expression patterns of the eye lens specific cytoskeletal proteins, CP49 and CP95, were determined for the chick and were found to be similar in both human and mouse. These proteins, as well as their homologs in ot
Publikováno v:
Current Eye Research. 16:838-846
To quantify the expression of beaded filament protein mRNA levels in regions of the chick lens and to examine the in vitro regulation of message and protein levels using cell culture techniques.RNase protection assays and Northern blotting were used
Autor:
Peter M. Corry, Yong J. Lee, Sandra Galoforo, Robert V. Blackburn, Joong M. Cho, Christine M. Berns, Mark E. Ireland
Publikováno v:
Molecular and Cellular Biochemistry. 155:51-60
We investigated the role of alpha B-crystallin expression in the development of thermotolerance in murine L929 cells. An initial heat-shock of 10 min at 45 degrees C induced thermotolerance in these cells to a heat challenge at 45 degrees C administe
Autor:
Mark E. Ireland, Julia E. Procter, Roy A. Quinlan, Woo-Kuen Lo, Ralf Dahm, Mette M. Mogensen, Alan R. Prescott
Publikováno v:
Experimental eye research. 85(5)
The differentiation of epithelial cells in the vertebrate lens involves a series of changes that includes the degradation of all intracellular organelles and a dramatic elongation of the cells. The latter is accompanied by a substantial remodelling o
Autor:
Mark E. Ireland
Publikováno v:
Experimental eye research. 80(3)
Autor:
Mark E. Ireland, Linda K. Mrock
Publikováno v:
Experimental eye research. 79(3)
The epidermal growth factor receptor is hypothesized to play an important role in the post-natal growth and differentiation of the ocular lens. Immunohistochemistry and western blotting were utilized to examine the distribution and activation of the
Autor:
Dawn M. Richiert, Mark E. Ireland
Publikováno v:
Current eye research. 19(3)
To determine if TGF-beta regulates the expression of metalloproteinases in chick lens annular pad cells.The activity of secreted matrix metalloproteinases was examined with gelatin zymography in primary cultures exposed to TGF-beta.Metalloproteinases
Publikováno v:
Current eye research. 18(3)
To refine the parameters affecting the accumulation of cytoskeletal markers of lens fiber terminal differentiation.Primary cultures of chick lens annular pad cells were treated with a lipid soluble cyclic AMP analog under various culture conditions.
Autor:
Mark E. Ireland, Dawn M. Richiert
Publikováno v:
Current eye research. 18(1)
To determine if the cataract forming influence of TGF-beta on lens cells is due to its effects on the ECM.Primary cultures of chick lens annular pad cells were exposed to TGF-beta and various exogenously supplied components of the lens capsule. Proli