Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mark E. Ashford"'
Autor:
Bo Zhang, Naresh Kumar, Naomi Wyatt, Wai Ching Cheah, Mohan M. Bhadbhade, Lynette C. Daws, Rheaclare Fraser-Spears, Nial J. Wheate, Paul D. Callaghan, Wouter Koek, Benjamin H. Fraser, Maxine P. Roberts, Mark E. Ashford, Anwen M. Krause-Heuer, Clarissa K. L. Ng, Georgianna G. Gould, Ivan Greguric, Jeremy C. Dobrowolski
Publikováno v:
European Journal of Medicinal Chemistry. 137:476-487
Herein we describe the synthesis and evaluation of antidepressant properties of seven analogues ( 1–7 ) of the low affinity/high capacity transporter blocker decynium-22 (D-22). All analogues ( 1–7 ) were synthesized via base promoted coupling re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e1d39e14cb4170a6786e2aee1946a1
https://doi.org/10.1016/j.ejmech.2017.06.011
https://doi.org/10.1016/j.ejmech.2017.06.011
Autor:
Benjamin H. Fraser, Ivan Greguric, Cathy D. Jiang, Anwen M. Krause-Heuer, Leena Hogan, Lidia Matesic, Andrew Katsifis, Vu Nguyen, Rodney J. Hicks, Marie-Claude Gregoire, Tien Q. Pham, Paula Berghofer, Delphine Denoyer, Maxine P. Roberts, Nigel A. Lengkeek, Stephen R. Taylor, Mark E. Ashford, Naomi Wyatt
Publikováno v:
Journal of Medicinal Chemistry. 58:6214-6224
This study reports the synthesis, [(123)I]radiolabeling, and biological profile of a new series of iodinated compounds for potential translation to the corresponding [(131)I]radiolabeled compounds for radionuclide therapy of melanoma. Radiolabeling w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9898816115aebcd799c2e3538e483b
https://doi.org/10.1021/acs.jmedchem.5b00777
https://doi.org/10.1021/acs.jmedchem.5b00777
Publikováno v:
Organicbiomolecular chemistry. 12(5)
5-Bromo-N-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-butyl)]-2,3-dimethoxybenzamide 1 is a potent and selective σ2 receptor ligand suitable for further development. A series of new analogues, incorporating a variety of isoquinoline and carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd41cc8e71b109ab4074e66039e9132
https://pubmed.ncbi.nlm.nih.gov/24306445
https://pubmed.ncbi.nlm.nih.gov/24306445
Autor:
MaxineP. Roberts, Vu Nguyen, Mark E. Ashford, Paula Berghofer, Naomi A. Wyatt, Anwen M. Krause-Heuer, Tien Q. Pham, StephenR. Taylor, Leena Hogan, Cathy D. Jiang, Benjamin H. Fraser, Nigel A. Lengkeek, Lidia Matesic, Marie-Claude Gregoire, Delphine Denoyer, RodneyJ. Hicks, Andrew Katsifis, Ivan Greguric
Publikováno v:
Journal of Medicinal Chemistry; Aug2015, Vol. 58 Issue 15, p6214-6224, 11p