Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Mark E. ADAMS"'
Autor:
Chris Christou, James Edwards, Michael Worthington, T. Surman, John F. Beltrame, John W. Finnie, Georgia Kate Williams, Jim Manavis, Angela Walls, Mark E. Adams, John M. Abrahams, Peter Frantzis
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 16, Iss 1, Pp 1-12 (2021)
Journal of Cardiothoracic Surgery
Journal of Cardiothoracic Surgery
Background In our earlier study on the functional limits of the aneurysmal aortic root we determined the pig root is susceptible to failure at high aortic pressures levels. We established a pig rupture model using cardiopulmonary bypass to determine
Autor:
Vijay K. Bhargava, Mark E. Adams
Publikováno v:
CCECE
Friendly jamming is a physical layer security technique that utilizes extra available nodes to jam any eavesdroppers. This paper considers the use of additional available nodes as friendly jammers in order to improve the security performance of a rou
Autor:
Vijay K. Bhargava, Mark E. Adams
Publikováno v:
VTC Fall
This paper presents the use of recursive least squares for online estimation of the self interference channel for an In Band Full Duplex communications link without the use of half duplex pilot signals. By using a long effective filter length it is p
Autor:
Petro Halkowycz, Hiroshi Miyake, Mark E. Adams, Shawn M. O’Connell, Michael B. Wallace, Lilly Zhang, Toufike Kanouni, Nicholas Scorah, Qing Dong, Lihong Shi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:2411-2414
The structure-based design, synthesis, and biological evaluation of two novel series of potent and selective MEK kinase inhibitors are described herein. The elaboration of a lead pyrrole derivative to a bicyclic dihydroindolone core provided compound
Autor:
Angela Vassar, Jeffrey N. Miner, Andrew R. Hudson, Mark E. Adams, Steven L. Roach, Dale E. Mais, Zhi Lin, Peter M. Syka, Keith B. Marschke, Robert I. Higuchi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:1697-1700
A series of tetrahydroquinoline derivatives were synthesized and profiled for their ability to act as glucocorticoid receptor selective modulators. Structure-activity relationships of the tetrahydroquinoline B-ring lead to the discovery of orally ava
Autor:
Lev N. Zakharov, Nadia Elia, Ryan White, Mark E. Adams, Arnold L. Rheingold, Richard S. Kelly, Daniel Murray, Mitchell R. Malachowski
Publikováno v:
Inorganica Chimica Acta. 362:1247-1252
Two nitrogen and sulfur containing ligands, 1-methyl-4-((4-methylimidazol-5-yl)methylthio)benzene (NS-mim) (1) and 1-methyl-4-(2-pyridylmethylthio)benzene (NS-mpy) (2) were synthesized and a series of their Cu(II) complexes, 3–10, prepared. The imi
Autor:
Mark E. Adams, Arnold L. Rheingold, Ashraf S. Kasto, Mitchell R. Malachowski, Lev N. Zakharov, Lawrence D. Margerum, Matthew J. Greaney
Publikováno v:
Polyhedron. 28:393-397
The novel pyrazole-containing tetradentate ligand 2,2′-bis[[(3,5-dimethylpyrazol-1-yl)methyl]amino]-1,1′-biphenyl (N4-mpz), 1, was synthesized and three Cu(II) complexes, 2–4, were prepared from this compound. These complexes were characterized
Autor:
Jyun-Hung Chen, Thomas R. Caferro, Charlotte Pooley Deckhut, Lin Zhi, Christopher M. Tegley, Keith B. Marschke, Anthony W. Thompson, James P. Edwards, E. Adam Kallel, Marquis L. Cummings, Francisco J. López, William T. Schrader, Robert I. Higuchi, Mark E. Adams, Donald S. Karanewsky
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5442-5446
A series of androgen receptor modulators based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones was synthesized and evaluated in an androgen receptor transcriptional activation assay. The most potent analogues from the series exhibited single-digit nanomolar
Autor:
Jeffrey N. Miner, Deepa Rungta, Lino J. Valdez, Yongkai Li, Andrew Hudson, William W. Lamph, Jean Yen, Dean P. Phillips, and Andrés Negro-Vilar, Lin Zhi, Angie Vassar, Catalina Cuervo, Reid P. Bissonnette, Keith B. Marschke, E. Adam Kallel, Mark E. Adams, Catherine J. Gharbaoui, Robert I. Higuchi, Dale E. Mais, Steven L. Roach
Publikováno v:
Journal of Medicinal Chemistry. 50:4699-4709
Structure-activity relationship studies centered around 3'-substituted (Z)-5-(2'-(thienylmethylidene))1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-chromeno[3,4-f]quinolines are described. A series of highly potent and efficacious selective glu
Publikováno v:
Arthritis & Rheumatism. 46:1536-1543
Objective Accurate assessment of chondrocyte metabolism is a potentially valuable indicator of cartilage health in osteoarthritis (OA). This study was conducted to explore the anabolic metabolism of chondrocytes early in the natural history of an exp