Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Mark E Reeves"'
Autor:
Huynh Cao, Do Hyun Kim, Ashley Howard, Hector Moz, Samiksha Wasnik, David J. Baylink, Chien-Shing Chen, Mark E Reeves, Saied Mirshahidi, Jeffrey Xiao, Olivia Francis, Guido Marcucci, Yi Xu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1252-1260 (2021)
T cell based immunotherapies can be applicable to acute myeloid leukemia (AML). Therefore, the selection of optimal T cells, cell manufacturing, and therapeutic T cell engineering are essential for the development of effective adoptive T cell therapi
Externí odkaz:
https://doaj.org/article/207d9563c96c4f869249a88fd26308d6
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101679 (2014)
RASSF1C is a major isoform of the RASSF1 gene, and is emerging as an oncogene. This is in contradistinction to the RASSF1A isoform, which is an established tumor suppressor. We have previously shown that RASSF1C promotes lung cancer cell proliferatio
Externí odkaz:
https://doaj.org/article/6c67de85c73a4179939ec06b7311d5b0
Autor:
Huynh Cao, Jeffrey Xiao, David J. Baylink, Vinh Nguyen, Nathan Shim, Jae Lee, Dave J. R. Mallari, Samiksha Wasnik, Saied Mirshahidi, Chien-Shing Chen, Hisham Abdel-Azim, Mark E. Reeves, Yi Xu
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2250 (2024)
Background: T-cell-based adoptive cell therapies have emerged at the forefront of cancer immunotherapies; however, failed long-term survival and inevitable exhaustion of transplanted T lymphocytes in vivo limits clinical efficacy. Leukemia blasts pos
Externí odkaz:
https://doaj.org/article/ebb1a91ed9ef452bb180d39522240859
Autor:
Yi Xu, David J. Baylink, Chien-Shing Chen, Laren Tan, Jeffrey Xiao, Brandon Park, Ismael Valladares, Mark E. Reeves, Huynh Cao
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Acute myeloid leukemia (AML) patients have frequent mutations in FMS-like receptor tyrosine kinase 3 (FLT3-mut AML), who respond poorly to salvage chemotherapies and targeted therapies such as tyrosine kinase inhibitors (TKIs). Disease relapse is a c
Externí odkaz:
https://doaj.org/article/04222e2a69dc42e88e95be578473bd6b
Autor:
Yousef G. Amaar, Mark E. Reeves
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 1113-1126 (2023)
The tumor microenvironment (TME) plays a vital role in tumor invasion and metastasis and provides a rich environment for identifying novel therapeutic targets. The TME landscape consists of an extracellular matrix (ECM) and stromal cells. ECM is a ma
Externí odkaz:
https://doaj.org/article/03422fb92b56456ea1dfaa612f7a41bf
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Understanding the factors which shape T-lymphocyte immunity is critical for the development and application of future immunotherapeutic strategies in treating hematological malignancies. The thymus, a specialized central lymphoid organ, plays importa
Externí odkaz:
https://doaj.org/article/3fe6b2fa0454464c816cdc5d965407f6
Autor:
Yi Xu, Christopher Hino, David J. Baylink, Jeffrey Xiao, Mark E. Reeves, Jiang F. Zhong, Saied Mirshahidi, Huynh Cao
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/cc0b5534a8bc40e2bb227d73dd9360dc
Autor:
Stephanie Y. Kwan, Dani Ran Castillo, Allison A. Aka, Gokul Kandala, James Y. Tsai, Kristine Zmaj, Mark E. Reeves, Gary Y. Yang
Publikováno v:
Journal of Gastrointestinal Oncology. 14:463-467
Autor:
Jack L. Richardson, Emily J. Levy, Riddhi Ranjithkumar, Huichun Yang, Eric Monson, Arthur Cronin, Jordi Galbany, Martha M. Robbins, Susan C. Alberts, Mark E. Reeves, Shannon C. McFarlin
Publikováno v:
Mammalian Biology. 102:615-627
Autor:
Tiantian Liu, Zhong Chen, Wanqiu Chen, Ryan Evans, Jane Xu, Mark E Reeves, Michael E de Vera, Charles Wang
Publikováno v:
Precision Clinical Medicine. 6
The desmoplastic and complex tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) has presented tremendous challenges for developing effective therapeutic strategies. Strategies targeting tumor stroma, albeit with great potential, have m