Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Mark E Olah"'
2
A New Intravenous Immune Globulin: Novel or Not?
Autor: Mark E Olah, Brittany N. Bates
Publikováno v: The Annals of pharmacotherapy. 55(1)
Objective: To assess the clinical use and determine the place in therapy for immune globulin intravenous (IV), human-slra, a recently approved IV immune globulin for the treatment of primary immune deficiency diseases (PIDD). Data Sources: A PubMed a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131ad02ad9881fec984083c24379bfe7
https://pubmed.ncbi.nlm.nih.gov/32567360
Zobrazit plný text záznamu
4
Coaggregation, Cointernalization, and Codesensitization of Adenosine A2A Receptors and Dopamine D2Receptors
Autor: Josefa Mallol, Kjell Fuxe, Michele Zoli, Anton Terasmaa, Rizaldy P. Scott, Stanley Watson, Maria Torvinen, Joëlle Hillion, Sergi Ferré, Mark E. Olah, Enric I. Canela, Carme Lluís, Meritxell Canals, Anita C. Hansson, Carlos F. Ibáñez, Vicent Casadó, Rafael Franco, Luigi F. Agnati
Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Antagonistic and reciprocal interactions are known to exist between adenosine and dopamine receptors in the striatum. In the present study, double immunofluorescence experiments with confocal laser microscopy showed a high degree of colocalization of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa44b87a6610428c6c3cc5a1b3a3105
https://doi.org/10.1074/jbc.m107731200
Zobrazit plný text záznamu
5
Selective A3 Adenosine Receptor Antagonists: Water-Soluble 3,5-Diacyl-1,2,4-trialkylpyridinium Salts and Their Oxidative Generation from Dihydropyridine Precursors
Autor: Rongyuan Xie, Neli Melman, Kenneth A. Jacobson, An-Hu Li, Xiao-duo Ji, Mark E. Olah, Gary L. Stiles
Publikováno v: Journal of Medicinal Chemistry. 42:4232-4238
A(3) adenosine receptor antagonists are sought for their potential antiinflammatory, antiasthmatic, and antiischemic properties. We have found that 3,5-diacyl-1,2,4-trialkyl-6-phenylpyridinium derivatives constitute a novel class of selective A(3) ad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9f4462db619aca94a231ea89d7655c
https://doi.org/10.1021/jm990234x
Zobrazit plný text záznamu
6
Identification of A2a Adenosine Receptor Domains Involved in Selective Coupling to GS
Autor: Mark E. Olah
Publikováno v: Journal of Biological Chemistry. 272:337-344
Responses to adenosine are governed by selective activation of distinct G proteins by adenosine receptor (AR) subtypes. The A2aAR couples via Gs to adenylyl cyclase stimulation while the A1AR couples to Gi to inhibit adenylyl cyclase. To determine re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c9d4c640ca45fdfbfa1f7edc7826a90
https://doi.org/10.1074/jbc.272.1.337
Zobrazit plný text záznamu
7
Survey of Nonxanthine Derivatives as Adenosine Receptor Ligands
Autor: Kenneth A. Jacobson, Siddiqi Sm, Marc Glashofer, William L. Padgett, Neli Melman, Louis A. Cohen, Gary L. Stiles, John W. Daly, Rahul Jain, Mark E. Olah, Xiao-duo Ji, Patricia M. Evans
Publikováno v: Nucleosides and Nucleotides. 15:693-717
The binding affinities at rat A1, A2a, and A3 adenosine receptors of a wide range of heterocyclic derivatives have been determined. Mono-, bi-, tricyclic and macrocyclic compounds were screened in binding assays, using either [3H]PIA or [3H]CGS 21680
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce385cc6fae0526060d1e5feed37143b
https://doi.org/10.1080/07328319608002416
Zobrazit plný text záznamu
8
Interaction of 1,4-Dihydropyridine and Pyridine Derivatives with Adenosine Receptors: Selectivity for A3 Receptors
Autor: A. M. Van Rhee, Neli Melman, Kenneth A. Jacobson, Jiang Ji-Long, Gary L. Stiles, Mark E. Olah
Publikováno v: Journal of Medicinal Chemistry. 39:2980-2989
1,4-Dihydropyridine and pyridine derivatives bound to three subtypes of adenosine receptors in the micromolar range. Affinity was determined in radioligand binding assays at rat brain A1 and A2A receptors using [3H]-(R)-PIA [[3H]-(R)-N6-(phenylisopro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54433ee46977d36bb561c7203fc69962
https://doi.org/10.1021/jm9600205
Zobrazit plný text záznamu
9
Search for New Purine- and Ribose-Modified Adenosine Analogs as Selective Agonists and Antagonists at Adenosine Receptors
Autor: J L Esker, Kenneth A. Jacobson, Siddiqi Sm, S W Schneller, Gloria Cristalli, Neli Melman, Kamal N. Tiwari, J A Secrist rd, Mark E. Olah, Xiao-duo Ji
Publikováno v: Journal of Medicinal Chemistry. 38:1174-1188
The binding affinities at rat A1, A2a, and A3 adenosine receptors of a wide range of derivatives of adenosine have been determined. Sites of modification include the purine moiety (1-, 3-, and 7-deaza; halo, alkyne, and amino substitutions at the 2-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddda70a9139b6c04adabb4c77fdd16d
https://doi.org/10.1021/jm00007a014
Zobrazit plný text záznamu
10
Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors
Autor: Kenneth A. Jacobson, Mark E. Olah, Gary L. Stiles
Publikováno v: Journal of Biological Chemistry. 269:24692-24698
Adenosine receptor (AR) agonists and antagonists are approximately 100-fold and 100,000-fold, respectively, more potent at the bovine A1AR as compared to the rat A3AR. To determine regions of ARs involved in ligand recognition, chimeric receptors com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9f4d2a4613dea1922a284bcfe26f43b
https://doi.org/10.1016/s0021-9258(17)31446-1
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje