Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Mark E J Woolhouse"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009189 (2021)
BackgroundThe antihelminthic drug praziquantel has been used as the drug of choice for treating schistosome infection for more than 40 years. Although some epidemiological studies have reported low praziquantel efficacy in cure rate (CR) and/or egg r
Externí odkaz:
https://doaj.org/article/1c684feefbbf4cd082e75796abce7de5
Autor:
Derick N M Osakunor, Takafira Mduluza, Douglas Osei-Hyiaman, Karl Burgess, Mark E J Woolhouse, Francisca Mutapi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008866 (2020)
Helminths are parasitic worms that infect over a billion people worldwide. The pathological consequences from infection are due in part, to parasite-induced changes in host metabolic pathways. Here, we analyse the changes in host metabolic profiles,
Externí odkaz:
https://doaj.org/article/e72f60c89df84b64a419231f7f283b65
Autor:
Feifei Zhang, Margo Chase-Topping, Chuan-Guo Guo, Bram A D van Bunnik, Liam Brierley, Mark E J Woolhouse
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009079 (2020)
RNA viruses are a leading cause of human infectious diseases and the prediction of where new RNA viruses are likely to be discovered is a significant public health concern. Here, we geocoded the first peer-reviewed reports of 223 human RNA viruses. U
Externí odkaz:
https://doaj.org/article/c89c7fd5e1534a48853a4d30b1be46ad
Autor:
Rivka M Lim, Mark E J Woolhouse, Takafira Mduluza, Margo Chase-Topping, Derick N M Osakunor, Lester Chitsulo, Francisca Mutapi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008650 (2020)
In 2012, the World Health Organisation (WHO) set out a roadmap for eliminating schistosomiasis as a public health problem by 2025. To achieve this target, preschool-aged children (PSAC; aged 6 years and below) will need to be included in schistosomia
Externí odkaz:
https://doaj.org/article/dc4f9f10b5b34b05890662d06317947c
Publikováno v:
PLoS Biology, Vol 17, Iss 11, p e3000206 (2019)
Novel infectious diseases continue to emerge within human populations. Predictive studies have begun to identify pathogen traits associated with emergence. However, emerging pathogens vary widely in virulence, a key determinant of their ultimate risk
Externí odkaz:
https://doaj.org/article/45fc9ec1d5ac4fa1a735338921569d09
Autor:
James M Hassell, PhD, Melissa J Ward, PhD, Dishon Muloi, DVM, Judy M Bettridge, PhD, Timothy P Robinson, PhD, Sam Kariuki, ProfPhD, Allan Ogendo, DVM, John Kiiru, PhD, Titus Imboma, MSc, Erastus K Kang'ethe, ProfPhD, Elin M Öghren, MSc, Nicola J Williams, ProfPhD, Michael Begon, ProfPhD, Mark E J Woolhouse, ProfPhD, Eric M Fèvre, ProfPhD
Publikováno v:
The Lancet Planetary Health, Vol 3, Iss 6, Pp e259-e269 (2019)
Summary: Background: Antimicrobial resistance is one of the great challenges facing global health security in the modern era. Wildlife, particularly those that use urban environments, are an important but understudied component of epidemiology of ant
Externí odkaz:
https://doaj.org/article/9f67077037c54eadbb3d8bfd9f80fee4
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 2, p e0006144 (2018)
Schistosomiasis affects over 200 million people worldwide, most of whom are children. Research and control strategies directed at preschool-aged children (PSAC), i.e., ≤5 years old, have lagged behind those in older children and adults. With the re
Externí odkaz:
https://doaj.org/article/d7c18da4c18f4c3cb7d0cb0a37af8117
Autor:
Kate M Mitchell, Francisca Mutapi, Takafira Mduluza, Nicholas Midzi, Nicholas J Savill, Mark E J Woolhouse
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e3059 (2014)
Previous studies suggest that protective immunity against Schistosoma haematobium is primarily stimulated by antigens from dying worms. Praziquantel treatment kills adult worms, boosting antigen exposure and protective antibody levels. Current schist
Externí odkaz:
https://doaj.org/article/9aa3d121d3cc43de9b382414d4e137eb
Autor:
M Carolyn Gates, Mark E J Woolhouse
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93410 (2014)
Farms that purchase replacement breeding cattle are at increased risk of introducing many economically important diseases. The objectives of this analysis were to determine whether the total number of replacement breeding cattle purchased by individu
Externí odkaz:
https://doaj.org/article/64d93b42df7e486bb493f4afdff516bf
Autor:
Samuel M Thumbi, Barend Mark de Clare Bronsvoort, Elizabeth Jane Poole, Henry Kiara, Philip G Toye, Mary Ndila Mbole-Kariuki, Ilana Conradie, Amy Jennings, Ian Graham Handel, Jacobus Andries Wynand Coetzer, Johan C A Steyl, Olivier Hanotte, Mark E J Woolhouse
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e76324 (2014)
In natural populations, individuals may be infected with multiple distinct pathogens at a time. These pathogens may act independently or interact with each other and the host through various mechanisms, with resultant varying outcomes on host health
Externí odkaz:
https://doaj.org/article/a556104bcbbf4a9f801764f25b81685b