Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mark Dysinger"'
Autor:
Yao Chen, Johanna R Mora, Russ Peloquin, Mark Dysinger, Karolina Österlund, Shobha Purushothama, Allison Given Chunyk
Publikováno v:
Bioanalysis. 10:181-194
This manuscript aims to provide insights and updates on emerging technologies from a throughput and multiplexing perspective and to update readers on changes in previously reported technologies. The technologies discussed range from nascent (ultrasen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8807ad7b9c925c845b98f248660bb888
https://doi.org/10.4155/bio-2017-0196
https://doi.org/10.4155/bio-2017-0196
Publikováno v:
Journal of Immunological Methods. 451:1-10
Biomarker quantitation with ligand binding assays has matured greatly in recent years. This maturation has been partly in response to demands for more data points from fewer samples or less available sample volume. Multiplexing offers opportunities t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db77040b997b6bba0e20f9184271eb4c
https://doi.org/10.1016/j.jim.2017.08.009
https://doi.org/10.1016/j.jim.2017.08.009
Publikováno v:
Current Issues in Ligand Binding Assay Bioanalysis. :168-180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed24320306a745dcab8e77aea8920b20
https://doi.org/10.4155/fseb2013.14.124
https://doi.org/10.4155/fseb2013.14.124
Autor:
Mark Dysinger, Mark Ma
Publikováno v:
The AAPS Journal. 20
Complement protein C5a is recognized as an important component of the alternative complement pathway. Its role is prominent enough to garner interest not only as a biomarker, but also as a potential therapeutic target. Bioanalytical challenges have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67aed190a13d11e131108eb675c53ab
https://doi.org/10.1208/s12248-018-0266-x
https://doi.org/10.1208/s12248-018-0266-x
Autor:
Alvydas Mikulskis, David Yeung, Dana L. Baker, Saloumeh K Fischer, Mark Dysinger, Alison Joyce, Andreas Jeromin, Allison Given Chunyk, Rosemary Lawrence-Henderson
Publikováno v:
The AAPS Journal. 20
An in-depth evaluation of the Quanterix© Simoa™ platform was undertaken by scientists from the AAPS Emerging Technologies Focus Group to determine the overall performance of the technology as well as provide guidance to future users. In order to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a162b80e3ec68f5443c0c4a52cbc1091
https://doi.org/10.1208/s12248-017-0156-7
https://doi.org/10.1208/s12248-017-0156-7
Autor:
Karolina Österlund, Johanna R Mora, Shobha Purushothama, Claude Ricks, Valerie Theobald, Mark Dysinger, Allison Given Chunyk
Publikováno v:
The AAPS Journal. 16:1175-1184
The purpose of this manuscript is to provide a summary of the evaluation done by the Throughput and Multiplexing subteam on five emerging technologies: Single molecule array (Simoa™), Optimiser™, CyTOF® (Mass cytometry), SQIDLite™, and iLite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8aa8887501389bb6c9cadd91704f11
https://doi.org/10.1208/s12248-014-9660-1
https://doi.org/10.1208/s12248-014-9660-1
Autor:
Mark Dysinger, Lindsay King
Publikováno v:
Journal of Immunological Methods. 379:30-41
Bio-layer interferometry (BLI) is a label-free technology that can be used for kinetic characterization of proteins. Although other label-free platforms have been used for quantitation purposes (most notably surface plasmon resonance), little work ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cad08e2e51d53376aaca06d6de080df
https://doi.org/10.1016/j.jim.2012.02.017
https://doi.org/10.1016/j.jim.2012.02.017
Autor:
Mark Dysinger
Publikováno v:
American Journal of Immunology. 8:71-77
As biomarkers grow in relevance for both the design and support of therapeutics and the clinical trials associated with them, there is an ever increasing need for accurate quantitation of these biochemical entities in biological matrices. While quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::106a0b2ffa228f1b68ab4bbb89f191f4
https://doi.org/10.3844/ajisp.2012.71.77
https://doi.org/10.3844/ajisp.2012.71.77
Publikováno v:
Journal of immunological methods. 407
There are a wide variety of ligand binding assay platforms available for implementation in present day bioanalytical laboratories. Selecting the platform that best suits a particular project's needs is highly dependent upon multiple assay characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34d3a0dbdbcb81cbf572fd4fb5d2098
https://pubmed.ncbi.nlm.nih.gov/24721392
https://pubmed.ncbi.nlm.nih.gov/24721392
Publikováno v:
Bioanalysis. 4(20)
Background: Plasma acyl and des-acyl ghrelin are thought of as components of total ghrelin, but this has never been validated using ex vivo spiking experiments, human sample collection comparisons and fit-for-purpose translatable assays. Results: Acy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1212208e7283f75efd849b2c526498
https://pubmed.ncbi.nlm.nih.gov/23157354
https://pubmed.ncbi.nlm.nih.gov/23157354