Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mark Duval"'
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
Innovative strategies are necessary to maximize the clinical application of HIV neutralizing antibodies. To this end, bispecific constructs of human antibody F240, reactive with well-conserved gp41 epitope and antibody 14A8, reactive with the IgA rec
Externí odkaz:
https://doaj.org/article/125927d0ef9a4fa6b6a1c9eba95a3880
Autor:
Joseph C. Martin, Ann Dauphin, Dale L. Greiner, Michael A. Brehm, Leonard D. Shultz, Lisa A. Cavacini, Aaron Wallace, Claudia Carbone, Mark Duval, Melissa A. Gawron, Jeremy Luban, Smita Jaiswal
Publikováno v:
The Journal of Immunology. 202:799-804
Broadly neutralizing, anti-HIV-1 gp120 monoclonal antibodies have been isolated from infected individuals, and there is considerable interest in developing these reagents for antibody-based immunoprophylaxis and treatment. As a means to identify pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1353feb63136af8f2a57bad7fb1750a
https://doi.org/10.4049/jimmunol.1801085
https://doi.org/10.4049/jimmunol.1801085
Autor:
Harry M. Meade, Kristin Joseph, Daniel Pollock, Mark Duval, Xiaocong Yu, Lisa A. Cavacini, Christopher J. Lewis
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 62:10-16
Background In some areas of the world, mother-to-child transmission of HIV remains a significant problem in part due to widespread breastfeeding, which is essential because of scarce supply of a safe replacement, protection conferred by breast milk a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e205934b0f065ebf805f924c935f2e
https://doi.org/10.1097/qai.0b013e318271c450
https://doi.org/10.1097/qai.0b013e318271c450
Autor:
John Smit, Marc S. Horwitz, John F. Nomellini, Christopher J. Lewis, Mark Duval, Lisa A. Cavacini
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:5547-5552
Innovative methods of prevention are needed to stop the more than two million new HIV-1 infections annually, particularly in women. Local application of anti-HIV antibodies has been shown to be effective at preventing infection in nonhuman primates;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c6cff4ac4ca5d58fe5803cc7bdc3c9
https://doi.org/10.1128/aac.00509-11
https://doi.org/10.1128/aac.00509-11
Autor:
Mukesh Kumar, Kailash C. Bhol, Mong-Shang Lin, Lisa A. Cavacini, Shih-Wei Yeh, Mark Duval, Marshall R. Posner, A. Razzaque Ahmed
Publikováno v:
Clinical Immunology. 120:68-75
Pemphigus vulgaris (PV) is a potentially fatal autoimmune mucocutaneous disease associated with production of IgG autoantibodies to desmoglein 3 (Dsg3), a 130-kDa epidermal cadherin protein. The binding of pathogenic antibody to Dsg3 on epidermal ker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff6e9a833d7e89572582ed0844d9de8
https://doi.org/10.1016/j.clim.2006.03.006
https://doi.org/10.1016/j.clim.2006.03.006
Autor:
Lisa A. Cavacini, Kenneth H. Mayer, Mark Duval, Charles E. Wood, Ajay Patil, Marshall R. Posner, Ruth M. Ruprecht
Publikováno v:
Journal of Medical Virology. 76:146-152
The identification of broadly reactive and cross-clade neutralizing antibodies will facilitate the development of a more universally effective vaccine for human immunodeficiency virus (HIV). Antibodies in sera from individuals infected with Clade B H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46d2b5c6a61c75d5fb4043370935fa2
https://doi.org/10.1002/jmv.20339
https://doi.org/10.1002/jmv.20339
Publikováno v:
AIDS Research and Human Retroviruses. 19:785-792
The IgG1 and IgG3 subclasses represent the predominant antibody response to viral infections, including HIV. IgG subclasses differ in their interaction with antigen and functional effects due to specific physiochemical features. With an elongated hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5105a13eea43791f606f38da8be85c3f
https://doi.org/10.1089/088922203769232584
https://doi.org/10.1089/088922203769232584
Autor:
Pablo Lopez Bergami, Mark Duval, Lisa A. Cavacini, David Kuhrt, Fangbing Liu, Marshall R. Posner
Publikováno v:
AIDS Research and Human Retroviruses. 19:597-607
Immunoglobulins undergo isotype switching in response to antigenic stimulation. The C(H) domains, in particular the hinge region, impose structural constraints on the interaction of antibody with antigen, especially multivalent antigens such as HIV.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56ca433056f4e78432349f981623bae
https://doi.org/10.1089/088922203322230969
https://doi.org/10.1089/088922203322230969
Autor:
Joseph Sodroski, Mark Duval, Shi Hua Xiang, Leslie Song, Rebecca Sangster, Marshall R. Posner, Lisa A. Cavacini
Publikováno v:
AIDS. 17:685-689
Objective: The HIV-1 env oligomer is structured such that conserved, neutralizing epitopes are obscured by gp120 variable loops. We have studied the ability of an IgG2 human monoclonal antibody (hmAb), F425 B4e8 (B4e8), dependent upon the base of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90c55b819b91d946ae0ac30cd757f66
https://doi.org/10.1097/00002030-200303280-00006
https://doi.org/10.1097/00002030-200303280-00006
Publikováno v:
AIDS. 16:2409-2417
Objective Development of an effective HIV vaccine has been limited because of the inherent structural properties of the HIV envelope on native virions and the failure of the immune system to respond in an effective manner. Identification of the inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7416407c43cd393406e8c0969837242f
https://doi.org/10.1097/00002030-200212060-00005
https://doi.org/10.1097/00002030-200212060-00005