Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Mark D. Shen"'
Autor:
Michael Yao, Jason Daniels, Luke Grosvenor, Valerie Morrill, Jason I. Feinberg, Kelly M. Bakulski, Joseph Piven, Heather C. Hazlett, Mark D. Shen, Craig Newschaffer, Kristen Lyall, Rebecca J. Schmidt, Irva Hertz-Picciotto, Lisa A. Croen, M. Daniele Fallin, Christine Ladd-Acosta, Heather Volk, Kelly Benke
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Common genetic variation has been shown to account for a large proportion of ASD heritability. Polygenic scores generated for autism spectrum disorder (ASD-PGS) using the most recent discovery data, however, explain less variance
Externí odkaz:
https://doaj.org/article/065b3e24ae6742c08b0d1d741348b431
Autor:
Aurora M. Washington, Amanda H. Mercer, Catherine A. Burrows, Stephen R. Dager, Jed T. Elison, Annette M. Estes, Rebecca Grzadzinski, Chimei Lee, Joseph Piven, John R. Pruett, Mark D. Shen, Benjamin Wilfond, Jason Wolff, Lonnie Zwaigenbaum, Katherine E. MacDuffie
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Emerging biomarker technologies (e.g., MRI, EEG, digital phenotyping, eye-tracking) have potential to move the identification of autism into the first year of life. We investigated the perspectives of parents about the anticipated
Externí odkaz:
https://doaj.org/article/f826b0fdd8c4490abfe6f481701140d9
Autor:
Lindsay J. Mullin, Joshua Rutsohn, Julia L. Gross, Kelly E. Caravella, Rebecca L. Grzadzinski, Leigh Anne Weisenfeld, Lisa Flake, Kelly N. Botteron, Stephen R. Dager, Annette M. Estes, Juhi Pandey, Robert T. Schultz, Tanya St. John, Jason J. Wolff, Mark D. Shen, Joseph Piven, Heather C. Hazlett, Jessica B. Girault
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Specifying early developmental differences among neurodevelopmental disorders with distinct etiologies is critical to improving early identification and tailored intervention during the first years of life. Recent studies have unc
Externí odkaz:
https://doaj.org/article/d59f7ad5836946faadab5014454a4f44
Autor:
Catherine A. Burrows, Carolyn Lasch, Julia Gross, Jessica B. Girault, Joshua Rutsohn, Jason J. Wolff, Meghan R. Swanson, Chimei M. Lee, Stephen R. Dager, Emil Cornea, Rebecca Stephens, Martin Styner, Tanya St. John, Juhi Pandey, Meera Deva, Kelly N. Botteron, Annette M. Estes, Heather C. Hazlett, John R. Pruett, Jr., Robert T. Schultz, Lonnie Zwaigenbaum, John H. Gilmore, Mark D. Shen, Joseph Piven, Jed T. Elison
Publikováno v:
Developmental Cognitive Neuroscience, Vol 65, Iss , Pp 101333- (2024)
Amygdala function is implicated in the pathogenesis of autism spectrum disorder (ASD) and anxiety. We investigated associations between early trajectories of amygdala growth and anxiety and ASD outcomes at school age in two longitudinal studies: high
Externí odkaz:
https://doaj.org/article/72d4bee043bb4e07bdab48bca710de56
Autor:
Jorrit Tjeertes, Carlos A. Bacino, Terry Jo Bichell, Lynne M. Bird, Mariana Bustamante, Rebecca Crean, Shafali Jeste, Robert W. Komorowski, Michelle L. Krishnan, Meghan T. Miller, David Nobbs, Cesar Ochoa-Lubinoff, Kimberly A. Parkerson, Alexander Rotenberg, Anjali Sadhwani, Mark D. Shen, Lisa Squassante, Wen-Hann Tan, Brenda Vincenzi, Anne C. Wheeler, Joerg F. Hipp, Elizabeth Berry-Kravis
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Background Angelman syndrome (AS) is a rare neurodevelopmental disorder characterized by the absence of a functional UBE3A gene, which causes developmental, behavioral, and medical challenges. While currently untreatable, comprehensive data
Externí odkaz:
https://doaj.org/article/ef450fe783de498baf723d4e7e4e74fb
Identification of subgroups of children in the Australian Autism Biobank using latent class analysis
Autor:
Alicia Montgomery, Anne Masi, Andrew Whitehouse, Jeremy Veenstra-VanderWeele, Lauren Shuffrey, Mark D. Shen, Lisa Karlov, Mirko Uljarevic, Gail Alvares, Sue Woolfenden, Natalie Silove, Valsamma Eapen
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract Background The identification of reproducible subtypes within autistic populations is a priority research area in the context of neurodevelopment, to pave the way for identification of biomarkers and targeted treatment recommendations. Few p
Externí odkaz:
https://doaj.org/article/cac1a4aa70a648138cded0700f427096
Autor:
Jessica B. Girault, Meghan R. Swanson, Shoba S. Meera, Rebecca L. Grzadzinski, Mark D. Shen, Catherine A. Burrows, Jason J. Wolff, Juhi Pandey, Tanya St John, Annette Estes, Lonnie Zwaigenbaum, Kelly N. Botteron, Heather C. Hazlett, Stephen R. Dager, Robert T. Schultz, John N. Constantino, Joseph Piven, for the IBIS Network
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background Younger siblings of children with autism spectrum disorder (ASD) are at increased likelihood of receiving an ASD diagnosis and exhibiting other developmental concerns. It is unknown how quantitative variation in ASD traits and bro
Externí odkaz:
https://doaj.org/article/e310c450f7e2469d9195292d1d9a6a98
Autor:
Liying Peng, Lanfen Lin, Yusen Lin, Yen-wei Chen, Zhanhao Mo, Roza M. Vlasova, Sun Hyung Kim, Alan C. Evans, Stephen R. Dager, Annette M. Estes, Robert C. McKinstry, Kelly N. Botteron, Guido Gerig, Robert T. Schultz, Heather C. Hazlett, Joseph Piven, Catherine A. Burrows, Rebecca L. Grzadzinski, Jessica B. Girault, Mark D. Shen, Martin A. Styner
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The infant brain undergoes a remarkable period of neural development that is crucial for the development of cognitive and behavioral capacities (Hasegawa et al., 2018). Longitudinal magnetic resonance imaging (MRI) is able to characterize the develop
Externí odkaz:
https://doaj.org/article/839b5da805714bb2b4b07799f1956afa
Autor:
Mark D. Shen
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background There is currently a renaissance of interest in the many functions of cerebrospinal fluid (CSF). Altered flow of CSF, for example, has been shown to impair the clearance of pathogenic inflammatory proteins involved in neurodegener
Externí odkaz:
https://doaj.org/article/d441ccb2d0c14439aa7ae413ac4d9daf
Autor:
Jessica B, Girault, Kevin, Donovan, Zoë, Hawks, Muhamed, Talovic, Elizabeth, Forsen, Jed T, Elison, Mark D, Shen, Meghan R, Swanson, Jason J, Wolff, Sun Hyung, Kim, Tomoyuki, Nishino, Savannah, Davis, Abraham Z, Snyder, Kelly N, Botteron, Annette M, Estes, Stephen R, Dager, Heather C, Hazlett, Guido, Gerig, Robert, McKinstry, Juhi, Pandey, Robert T, Schultz, Tanya, St John, Lonnie, Zwaigenbaum, Alexandre, Todorov, Young, Truong, Martin, Styner, John R, Pruett, John N, Constantino, Joseph, Piven
Publikováno v:
The American journal of psychiatry. 179(8)
Autism spectrum disorder (ASD) is heritable, and younger siblings of ASD probands are at higher likelihood of developing ASD themselves. Prospective MRI studies of siblings report that atypical brain development precedes ASD diagnosis, although the l