Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mark D. Bunting"'
Autor:
Mark D. Bunting, Gelshan I. Godahewa, Nicole O. McPherson, Louise J. Robertson, Luke Gierus, Sandra G. Piltz, Owain Edwards, Mark Tizard, Paul Q. Thomas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract CRISPR-Cas9 technology has facilitated development of strategies that can potentially provide more humane and effective methods to control invasive vertebrate species, such as mice. One promising strategy is X chromosome shredding which aims
Externí odkaz:
https://doaj.org/article/63bfc6cc0bcd476ea67cb68e6be72ee9
Autor:
Luke Gierus, Aysegul Birand, Mark D. Bunting, Gelshan I. Godahewa, Sandra G. Piltz, Kevin P. Oh, Antoinette J. Piaggio, David W. Threadgill, John Godwin, Owain Edwards, Phillip Cassey, Joshua V. Ross, Thomas A. A. Prowse, Paul Q. Thomas
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(46)
Invasive rodents, including house mice, are a major cause of environmental damage and biodiversity loss, particularly in island ecosystems. Eradication can be achieved through the distribution of rodenticide, but this approach is expensive to apply a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b673725f149b6f61f4276b184b10d7
https://pubmed.ncbi.nlm.nih.gov/36595707
https://pubmed.ncbi.nlm.nih.gov/36595707
Autor:
Mark D, Bunting, Chandran, Pfitzner, Luke, Gierus, Melissa, White, Sandra, Piltz, Paul Q, Thomas
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2495
Gene drives are genetic elements that are transmitted to greater than 50% of offspring and have potential for population modification or suppression. While gene drives are known to occur naturally, the recent emergence of CRISPR-Cas9 genome-editing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcf5488170ac44b02acaf773a73b7b2d
https://pubmed.ncbi.nlm.nih.gov/35696035
https://pubmed.ncbi.nlm.nih.gov/35696035
Autor:
Mark D. Bunting, Maulik Vyas, Marta Requesens, Adam Langenbucher, Erik B. Schiferle, Robert T. Manguso, Michael S. Lawrence, Shadmehr Demehri
Publikováno v:
Science advances. 8(11)
Natural killer (NK) cells reject major histocompatibility complex class I (MHC-I)–deficient bone marrow through direct cytotoxicity but not solid organ transplants devoid of MHC-I. Here, we demonstrate an immediate switch in NK cell function upon e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee049d25f146de87de17cc52353fbafc
https://pubmed.ncbi.nlm.nih.gov/35294229
https://pubmed.ncbi.nlm.nih.gov/35294229
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623008
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::566aa632329ae1518f27328576f56897
https://doi.org/10.1007/978-1-0716-2301-5_11
https://doi.org/10.1007/978-1-0716-2301-5_11
Autor:
Peter Hoffmann, Mark D. Bunting, Ervin E. Kara, Iain Comerford, Sapna Devi, Lynn Tolley, Clifford Young, Cameron R. Bastow, Mark R. Condina, Shaun R. McColl, Duncan R. McKenzie, Scott N. Mueller, Natasha L. Harvey, Ian H. Frazer, Adriana C. Caon
Publikováno v:
Proc Natl Acad Sci U S A
Leukocyte homing driven by the chemokine CCL21 is pivotal for adaptive immunity because it controls dendritic cell (DC) and T cell migration through CCR7. ACKR4 scavenges CCL21 and has been shown to play an essential role in DC trafficking at the ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5699a20596e0a5883db90b019f3a1c
https://hdl.handle.net/11541.2/148072
https://hdl.handle.net/11541.2/148072
Autor:
Peter Fleming, Antiopi Varelias, Siok-Keen Tey, Mariapia A. Degli-Esposti, Kelli P. A. MacDonald, Bruce R. Blazar, Fernando Souza-Fonseca-Guimaraes, Rachel D. Kuns, Mark J. Smyth, Kelly R. Locke, Geoffrey R. Hill, Steven W. Lane, Katie E. Lineburg, Nicholas D. Huntington, Iona S. Schuster, Mark D. Bunting
Publikováno v:
Blood. 129:630-642
Allogeneic bone marrow transplantation (allo-BMT) is a curative therapy for hematological malignancies, but is associated with significant complications, principally graft-versus-host disease (GVHD) and opportunistic infections. Natural killer (NK) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1236d3e9e7f21a234f65feeef0b2212
https://doi.org/10.1182/blood-2016-08-734020
https://doi.org/10.1182/blood-2016-08-734020
Autor:
Bianca E. Teal, Mark J. Smyth, Katie E. Lineburg, Kate A. Markey, Glen M. Boyle, Shaun R. McColl, Neil C. Raffelt, Antiopi Varelias, Mark D. Bunting, James McCluskey, Motoko Koyama, Jamie Rossjohn, Mary Lor, Brigitta Stockinger, Kelli P. A. MacDonald, Geoffrey R. Hill, Steven W. Lane, Rachel D. Kuns, Stuart D. Olver, Melody Cheong, Michele W.L. Teng, Iain Comerford, Andrew D. Clouston, Kate H. Gartlan
Publikováno v:
Blood. 126:1609-1620
IL-17-producing cells are important mediators of graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (SCT). Here we demonstrate that a distinct CD8(+) Tc17 population develops rapidly after SCT but fails to maintain lineage fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a7a27ac3aa9c2cc314008ec2644b62
https://doi.org/10.1182/blood-2015-01-622662
https://doi.org/10.1182/blood-2015-01-622662
Autor:
Ping Zhang, Bianca E. Teal, Rachel D. Kuns, Antiopi Varelias, Kelli P. A. MacDonald, Mark D. Bunting, Katie E. Lineburg, Christian R. Engwerda, Shaun R. McColl, Leesa F. Wockner, Kelly R. Locke, Kate A. Markey, Gabrielle T. Belz, Geoffrey R. Hill, Kate H. Gartlan, Motoko Koyama, Slavica Vuckovic, Lucie Leveque-El Mouttie, Melody Cheong, Michele W.L. Teng, Siok-Keen Tey, Mark J. Smyth
Publikováno v:
The Journal of Experimental Medicine
Koyama et al. show that GVHD markedly enhances alloantigen presentation within the mesenteric lymph nodes, mediated by donor CD103+CD11b− DCs that migrate from the colon under the influence of CCR7. This antigen presentation imprints gut-homing int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c716c3585e6a3748701a9c4f24cadde
https://doi.org/10.1084/jem.20150329
https://doi.org/10.1084/jem.20150329
Autor:
Jamie Rossjohn, Motoko Koyama, Nancy Lachner, Kate L. Ormerod, Renee J. Robb, Geoffrey R. Hill, James McCluskey, Steven W. Lane, Lars Kjer-Nielsen, Philip Hugenholtz, Kate H. Gartlan, Rachel D. Kuns, Andrea S. Henden, Antiopi Varelias, Mark D. Bunting, Jeffrey Y. W. Mak, David P. Fairlie, Stuart D. Olver, Leanne Cooper, Andrew D. Clouston, Olivier Lantz, Jasmin Straube
Publikováno v:
The Journal of clinical investigation. 128(5)
Mucosal-associated invariant T (MAIT) cells are a unique innate-like T cell subset that responds to a wide array of bacteria and yeast through recognition of riboflavin metabolites presented by the MHC class I-like molecule MR1. Here, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c447c8c7f89d38e63e67b9f62f1d3176
https://pubmed.ncbi.nlm.nih.gov/29629900
https://pubmed.ncbi.nlm.nih.gov/29629900