Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mark D Winemiller"'
Autor:
Caroline Langley, Sue Y Bae, Jonah Cheung, Scott D. Pegan, J.J. Height, Mark D Winemiller, Vanessa L Funk, Mark A. Guelta, J.R. McGuire, S.M. Bester, James M. Myslinski
Publikováno v:
Chemical Research in Toxicology. 34:804-816
The recent use of organophosphate nerve agents in Syria, Malaysia, Russia, and the United Kingdom has reinforced the potential threat of their intentional release. These agents act through their ability to inhibit human acetylcholinesterase (hAChE; E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c840e3110b59e82d39762b12fd214e
https://doi.org/10.1021/acs.chemrestox.0c00406
https://doi.org/10.1021/acs.chemrestox.0c00406
Autor:
Stephanie M. Bester, Mark A. Guelta, Jonah Cheung, Mark D. Winemiller, Su Y. Bae, James Myslinski, Scott D. Pegan, Jude J. Height
Publikováno v:
Chemical Research in Toxicology. 31:1405-1417
Over 50 years ago, the toxicity of irreversible organophosphate inhibitors targeting human acetylcholinesterase (hAChE) was observed to be stereospecific. The therapeutic reversal of hAChE inhibition by reactivators has also been shown to depend on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f1c8ce3f900396fc952c7e98d72db7
https://doi.org/10.1021/acs.chemrestox.8b00294
https://doi.org/10.1021/acs.chemrestox.8b00294
Autor:
Mark D. Winemiller, Sue Y. Bae
Publikováno v:
Journal of agricultural and food chemistry. 66(29)
Ultra-Performance Liquid Chromatography/electrospray ionization mass spectrometry was used for the trace level determination of isopropyl methylphosphonofluoridate (Sarin, GB) and ( O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate (VX) af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762f955755a140e70a156e62e1a81c99
https://pubmed.ncbi.nlm.nih.gov/29920090
https://pubmed.ncbi.nlm.nih.gov/29920090
Autor:
Mark D Winemiller, Sue Y Bae
Liquid chromatographyelectrospray ionization mass spectrometry with positive-ion modes of operation were used for the trace-level determination of isopropyl methylphosphonofluoridate (sarin, GB) in various food matrices. The development of a solid-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad90c44480e173ef944824ed9d62a43
https://doi.org/10.21236/ad1004032
https://doi.org/10.21236/ad1004032
The electron impact and collision-induced-dissociation mass spectra of 1-(2-chloroethoxy)-2-[(2-chloroethyl)thio] ethane and 10 related molecules were obtained using gas chromatographymass spectrometry and gas chromatographytriple-quadrupole mass spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a49e403829d6fd97333efb124603931
https://doi.org/10.21236/ad1003011
https://doi.org/10.21236/ad1003011
The electron impact (EI) and collision-ion-dissociation (CID) mass spectra of 1-(2-chloroethoxy)-2-[(2-chloroethyl) thio]ethane (1) and ten related molecules were obtained using gas chromatography-mass spectrometry (GC-MS) and gas chromatography-trip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceda7c9fbb2cfb636b4101a9fb9260f9
Autor:
Sue Y Bae, Mark D Winemiller
Liquid chromatography--electrospray ionization mass spectrometry with positive-ion modes of operation was used to analyze several V-type chemical warfare agents (VX, RVX, CVX, and VM) in various food matrices. The development of a solid-phase extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87210476e56f1bf581eb2922854d289c
https://doi.org/10.21236/ada625585
https://doi.org/10.21236/ada625585
Autor:
Mark D. Winemiller, Kenneth B. Sumpter
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 183:2309-2317
A degradation product of sulfur mustard in ton storage containers 1-(2-chloroethoxy)-2-[(2-chloroethyl)thio] ethane (little “t”) has been synthesized and characterized along with a number of its derivatives and related compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2cecb71e4ce2a50833cb8138ae7cf4
https://doi.org/10.1080/10426500801963582
https://doi.org/10.1080/10426500801963582
Publikováno v:
The Journal of Organic Chemistry. 66:6291-6298
Low-temperature (6)Li, (13)C, and (15)N NMR spectroscopies reveal that mixtures of lithium cyclopropylacetylide or lithium phenylacetylide (RCCLi) and a vicinal amino alkoxide derived from camphor (R*OLi) in THF/pentane afford an asymmetric (RCCLi)(3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc093666e5d2231fba5495bfb530cc07
https://doi.org/10.1021/jo010305b
https://doi.org/10.1021/jo010305b
Autor:
Mark D. Winemiller, William A. Nugent, Bosong Xiang, David B. Collum, Rodney L. Parsons, Roberta L. Dorow, Joseph M. Fortunak, Goss S. Kauffman, Gregory D. Harris, Timothy F. Briggs
Publikováno v:
Journal of the American Chemical Society. 123:9135-9143
The solution structures of mixed aggregates derived from lithium alkoxides and lithium acetylides were investigated as part of a program to develop practical syntheses of quinazolinone-based nonnucleoside reverse transcriptase inhibitors. Low-tempera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948417efbfa9ffcc7a76517800563dd1
https://doi.org/10.1021/ja0105616
https://doi.org/10.1021/ja0105616