Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark D Stump"'
Autor:
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson, Rebecca Ward, Kelli A Monaco, Joshua Korn, John E Monahan, Mark D Stump, Felipa A Mapa, Christopher J Wilson, Janine Steiger, Jebediah Ledell, Richard J Rickles, Vic E Myer, Seth A Ettenberg, Robert Schlegel, William R Sellers, Heather A Huet, Joseph Lehár
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146635 (2016)
Externí odkaz:
https://doaj.org/article/59c3f93f2d5c4482aef340a64a791f66
Autor:
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson, Rebecca Ward, Kelli A Monaco, Joshua Korn, John E Monahan, Mark D Stump, Felipa A Mapa, Christopher J Wilson, Janine Steiger, Jebediah Ledell, Richard J Rickles, Vic E Myer, Seth A Ettenberg, Robert Schlegel, William R Sellers, Heather A Huet, Joseph Lehár
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138486 (2015)
Death Receptor 5 (DR5) agonists demonstrate anti-tumor activity in preclinical models but have yet to demonstrate robust clinical responses. A key limitation may be the lack of patient selection strategies to identify those most likely to respond to
Externí odkaz:
https://doaj.org/article/65b59ba5d911495fa33f7b9acb527174
Autor:
David J. Gregory, Augustin Vannier, Akiro H. Duey, Tyler J. Roady, Richard K. Dzeng, Maia N. Pavlovic, Michael H. Chapin, Sonia Mukherjee, Hannah Wilmot, Nic Chronos, Richelle C. Charles, Edward T. Ryan, Regina C. LaRocque, Tyler E. Miller, Wilfredo F. Garcia-Beltran, Julia C. Thierauf, A. John Iafrate, Steven Mullenbrock, Mark D. Stump, Randall K. Wetzel, Roberto D. Polakiewicz, Vivek Naranbhai, Mark C. Poznansky
Publikováno v:
Virulence. 13:890-902
Antibodies to SARS-CoV-2 are central to recovery and immunity from COVID-19. However, the relationship between disease severity and the repertoire of antibodies against specific SARS-CoV-2 epitopes an individual develops following exposure remains in
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
XLSX file - 243KB, This table summarizes all significant genetic features that differentiate sensitive versus insensitive cell lines for TNKSi/MEKi combination. The first sheet lists all cell lines for each group. The second sheet lists all genetic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98357659919c6a16595e1f40b492fc17
https://doi.org/10.1158/0008-5472.22403508
https://doi.org/10.1158/0008-5472.22403508
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
PDF file - 68KB, Sensitivity of KRAS mutant cancer cells to TNKSi/MEKi combination. Synergistic cell lines are in red (cut-off of synergy score of 2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120c66d80736a8add956ce74f2e65cef
https://doi.org/10.1158/0008-5472.22403499
https://doi.org/10.1158/0008-5472.22403499
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
PDF file - 660KB, Supplementary Figure S1. All RAS mutant cell lines have a higher sensitivity to the TNKSi/MEKi combination. Supplementary Figure S2. Validation of TNKSi/MEKi combination in KRAS mutant cancer cells. Supplementary Figure S3. Combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c1ed739870295e826b9ca06823f4d0
https://doi.org/10.1158/0008-5472.22403517
https://doi.org/10.1158/0008-5472.22403517
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
PDF file - 123KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6336a2bcc1da4dd884ed5a8e2e5bc15e
https://doi.org/10.1158/0008-5472.22403514.v1
https://doi.org/10.1158/0008-5472.22403514.v1
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
XLSX file - 234KB, This table shows the features of all 138 cancer cell lines tested for the TNKSi/MEKi combination in the unbiased combination screen. Cell line name, lineage, RAS mutation status and synergy score for the TNKSi/MEKi combination are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db7d3ec112a125f2445b5deec1997a5
https://doi.org/10.1158/0008-5472.22403505
https://doi.org/10.1158/0008-5472.22403505
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
PDF file - 81KB, List of identified synergistic cell lines for TNKSi/MEKi combination in the large-scale combination screen and their KRAS status. KRAS mutants are in red.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0426140421e712ad5e07a2c175811e44
https://doi.org/10.1158/0008-5472.22403511.v1
https://doi.org/10.1158/0008-5472.22403511.v1
Autor:
Wenlin Shao, Nika N. Danial, William R. Sellers, Mark D. Stump, Jebediah Ledell, Janine Steiger, Vesselina G. Cooke, Brandon Antonakos, Michael D. Jones, Daisy Flemming, Joshua M. Korn, Dmitriy Sonkin, Yuji Mishina, Yan Yan-Neale, Joseph Lehár, Kristen E. Hurov, Marie Schoumacher
PDF file - 54KB, Chemical inhibitors used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11140634b75740d3e8b5e2937cdb67b
https://doi.org/10.1158/0008-5472.22403502.v1
https://doi.org/10.1158/0008-5472.22403502.v1